Celia Gregson completed a Wellcome Trust Clinical Research Training Fellowship which included a one year full-time MSc in epidemiology at the London School of Hygiene and Tropical Medicine (LSHTM) followed by a PhD at the University of Bristol. She currently works as a Senior Scientist at the MRC Lifecourse Epidemiology Unit at the University of Southampton and as a consultant geriatrician at the Royal United Hospital in Bath. In 2013 she will take up an Arthritis Research UK clinician scientist fellowship at the University of Bristol. Her research interests include high bone mass, genetic epidemiology of bone disease, body composition and bone

Epidemiology of bone disease

Frysz, M, Deere, K, Lawlor, D, Benfield, L, Tobias, J & Gregson, C, 2016, ‘Bone mineral density is positively related to carotid intima-media thickness: findings from a population based study in adolescents and premenopausal women’. Journal of Bone & Mineral Research. Gaskell, N, Choulerton, J, Shaw, L & Gregson, C, 2016, ‘Fracture risk and bone health following a stroke are inadequately considered by physicians: A UK survey of practice’. European Geriatric Medicine. Zheng, H-F, Forgetta, V, Hsu, Y-H, Estrada, K, Rosello-Diez, A, Leo, PJ, Dahia, CL, Park-Min, KH, Tobias, JH, Kooperberg, C, Kleinman, A, Styrkarsdottir, U, Liu, C-T, Uggla, C, Evans, DS, Nielson, CM, Walter, K, Pettersson-Kymmer, U, McCarthy, S, Eriksson, J, Kwan, T, Jhamai, M, Trajanoska, K, Memari, Y, Min, J, Huang, J, Danecek, P, Wilmot, B, Li, R, Chou, W-C, Mokry, LE, Moayyeri, A, Claussnitzer, M, Cheng, C-H, Cheung, W, Medina-Gómez, C, Ge, B, Chen, S-H, Choi, K, Oei, L & others 2015, ‘Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture’. Nature, vol 526., pp. 112-7 Gregson, CL, Wheeler, L, Hardcastle, SA, Appleton, LH, Addison, KA, Brugmans, M, Clark, GR, Ward, K, Paggiosi, M, Stone, M, Thomas, J, Agarwal, R, Poole, K, McCloskey, E, Fraser, WD, Williams, E, Bullock, AN, Smith, GD, Brown, MA, Tobias, JH & Duncan, EL, 2015, ‘Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass cases’. Journal of Bone & Mineral Research, vol 31., pp. 640-649 Hardcastle, SA, Dieppe, P, Gregson, CL, Arden, NK, Spector, TD, Hart, DJ, Edwards, MH, Dennison, EM, Cooper, C, Sayers, A, Williams, M, Smith, GD & Tobias, JH, 2015, ‘Individuals with high bone mass have an increased prevalence of radiographic knee osteoarthritis’. Bone, vol 71., pp. 171-9 White, SL, Jacob, A, Gregson, C & Bhalla, A, 2015, ‘Severe polyarthritis secondary to zolendronic acid: a case report and literature review’. Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases, vol 12., pp. 69-74 Hardcastle, SA, Dieppe, P, Gregson, CL, Smith, GD & Tobias, JH, 2015, ‘Osteoarthritis and bone mineral density: are strong bones bad for joints?’. BoneKEy reports, vol 4., pp. 624 Loh, NY, Neville, MJ, Marinou, K, Hardcastle, SA, Fielding, BA, Duncan, EL, McCarthy, MI, Tobias, JH, Gregson, CL, Karpe, F & Christodoulides, C, 2015, ‘LRP5 Regulates Human Body Fat Distribution by Modulating Adipose Progenitor Biology in a Dose- and Depot-Specific Fashion’. Cell Metabolism, vol 21., pp. 262-72 Moon, RJ, Cole, ZA, Crozier, SR, Curtis, EM, Davies, JH, Gregson, CL, Robinson, SM, Dennison, EM, Godfrey, KM, Inskip, HM, Cooper, C, Harvey, NC & , 2015, ‘Longitudinal changes in lean mass predict pQCT measures of tibial geometry and mineralisation at 6-7years’. Bone. Hardcastle, SA, Gregson, CL, Rittweger, J, Crabtree, N, Ward, K & Tobias, JH, 2014, ‘Jump power and force have distinct associations with cortical bone parameters: Findings from a population enriched by individuals with high bone mass’. Journal of Clinical Endocrinology and Metabolism, vol 99., pp. 266-275