In 1990 Dr Gallacher jointly led the first group in the UK to report the production of catalytic antibodies.

Synthetic Organic Chemistry - Design and synthesis of haptens, immunogens, prodrugs, and transition-state analogue inhibitors. Bio Organic Chemistry - Catalytic antibodies Medicinal Chemistry - Prodrugs and drug targetting (cancer). Immuno Chemistry - Generation of antibodies for the treatment of autoimmune diseases and poisoning

Boucher, G., Said, B., Ostler, Elizabeth, Resmini, M., Brocklehurst, K. and Gallacher, Gerard (2007) Evidence that the mechanism of antibody-catalysed hydrolysis of arylcarbamates can be determined by the structure of the immunogen used to elicit the catalytic antibody Biochemical Journal, 401 (3). pp. 721-726. ISSN 1470-8728 Sonkaria, S., Boucher, G., Florez-Alvarez, J., Said, B., Hussain, S., Ostler, Elizabeth, Gul, S., Thomas, E.W., Resmini, M., Gallacher, Gerard and Brocklehurst, K. (2004) Evidence for ‘lock and key’ character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes Biochemical Journal, 381 (1). pp. 125-130. ISSN 1470-8728 Gul, S., Sonkaria, S., Pinitglang, S., Florez-Alvarez, J., Hussain, S., Thomas, E.W., Ostler, Elizabeth, Gallacher, Gerard, Resmini, M. and Brocklehurst, K. (2003) Improvement in hydrolytic antibody activity by change in haptenic structure from phosphate to phosphonate with retention of a common leaving-group determinant: evidence for the ‘flexibility’ hypothesis Biochemical Journal, 376 (3). pp. 813-821. ISSN 1470-8728 Ostler, Elizabeth, Resmini, M., Brocklehurst, K. and Gallacher, Gerard (2002) Polyclonal catalytic antibodies Journal of Immunological Methods, 269 (1-2). pp. 111-124. ISSN 0022-1759 Ostler, Elizabeth, Dean, C.J., Barber, N., Valeri, M., James, Stuart, Resmini, M., Boucher, G., Romanov, N., Brocklehurst, K. and Gallacher, Gerard (2002) A rat monoclonal antibody that catalyses the hydrolysis of a nitrophenyl-β-lactam Biochemical and Biophysical Research Communications, 299 (2). pp. 273-276. ISSN 0006-291X Florez-Alvarez, J., Brocklehurst, K., Gallacher, Gerard and Resmini, M. (2002) Synthesis of an aminoalcohol hapten for the generation of catalytic antibodies Tetrahedron Letters, 43 (1). pp. 171-174. ISSN 0040-4039 Ostler, Elizabeth, Resmini, M., Boucher, G., Romanov, N., Brocklehurst, K. and Gallacher, Gerard (2002) Polyclonal antibody-catalysed hydrolysis of a beta-lactam Chemical Communications, 3. pp. 226-227. ISSN 1359-7345