MD, Heinrich-Heine Universität Düsseldorf, Germany, 1999

Cytokines and their (soluble) receptors act in a complex network which makes it difficult to predict the outcome of blocking a single component. The most suitable mediator to target may differ between individual patients and disease stages. A number of novel therapies have recently been developed for psoriasis, which target a specific cytokine or its receptor but we clearly need deeper knowledge to truly individualise therapy so each patients receives the treatment which is most efficient for his/her disease subtype (= precision medicine approach). Our work aims to gain even better insight into the skin cytokine network in inflammatory skin conditions and to identify how to select the best treatment approach

Inflammatory Skin Disease; Dermatology; Lupus erythematosus, psoriasis, eczema