University of Bradford, School of Life Sciences (PhD, 2013) University of Bradford, School of Computing, Informatics and Media (MPhil, 2010) University of Wroclaw, Institute of Mathematics (MSc, 2005)

Bioinformatics of Genomics and Epigenomics- Epigenomics of the Skin development and Disorders- Big biomedical Data Analytics Development of bioinformatics worflows

Bioinformatics, Biostatistics, Digital health, Epigenetics, Genomics, Skin

Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA. "Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium". J Cell Biol. 2016 Ahmed MI, Alam M, Emelianov VU, Poterlowicz K, Patel A, Sharov AA, Mardaryev, AN, Botchkareva NV. "MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway". J Cell Biol. 2014 T.Y. Sharova,K. Poterlowicz, N.V. Botchkareva , N.A. Kondratiev, A. Aziz, J.H. Spiegel, V.A. Botchkarev, A.A. Sharov "Complex changes in the apoptotic and cell differentiation programs duri ng initiation of the hair follicle response to chemotherapy" , Journal of Investigative Dermatology, 2014 A.N. Mardaryev, M.R. Gdula , J.L. Yarker , V.N. Emelianov, K. Poterlowicz , A.A. Sharov, T.Y. Sharova, J.A. Scarpa, P. Chambon, V.A. Botchkarev, M.Y. Fessing "p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells", Development, 2014 C.J. Lewis, A.N. Mandrayev, K. Poterlowicz, T.Y. Sharova, A. Aziz, D.T. Sharpe, N.V. Botchkareva, A.A Sharov “Bone Morphogenetic Protein Signalling Suppresses wound-Induced Skin Repair by Inhibiting Keratinocyte Proliferation and Migration”, Journal of Investigative Dermatology, 2013 M.R. Gdula, K. Poterlowicz, A.N. Mandrayev, A.A. Sharov, Y. Peng, M.Y. Fessing, V.A. Botchkarev “Remodelling of three-dimensional organization of the nucleus during terminal keratinocyte differentiation in the epidermis”, Journal of Investigative Dermatology, 2013 T. Kohwi-Shigematsu, K. Poterlowicz, E. Ordinario, H.J. Han, V.A. Botchkarev, Y. Kohwi “Genome organizing function of SATB1 in tumor progression.” Seminars in Cancer Biology, 2012 J. Laubenthal, O. Zlobinskaya*, K. Poterlowicz*, M.R. Gdula, J.O. Linschooten, E. Fthenou, A. Baumgartner, F.J. van Schooten, T.E. Schmid, R.W. Godschalk and D. Anderson “Cigarette smoke-induced transgenerational alterations in genome stability in cord blood of human F1 offspring”, FASEB, 2012 Oct:26(10):3946-56 (* equal contribution) K.M. McMahon, M. Volpato, H.Y. Chi, P. Musiwaro, K. Poterlowicz, Y. Peng, A.J. Scally, L.H. Patterson, R.M. Phillips, C.W. Sutton “Characterization of changes in the proteome in different regions of 3D multicell tumor spheroids” Journal of Proteome Research, 2012 May;11(5):2863-75 A.N. Mandrayev, N. Meier, K. Poterlowicz, A.A. Sharov, T. Sharova, M.I. Ahmed, V. Rapisarda, C. Lewis, M.Y. Fessing, T.M. Ruenger, J. Bhawan, S. Werner, R. Paus and V.A. Botchkarev “Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after Injury” Development, 2011 Nov;138(22):4843-52 M.Y. Fessing, A.N. Mandrayev, M.R. Gdula, A.A. Sharov, T Sharova, V. Rapisadra, K.B. Gordon, A.D Smorodchenko, K. Poterlowicz, G. Ferone, Y. Kohwi, C. Missero, T. Kohwi-Shigematsu and V.A. Botchkarev “p63 Regulates Satb1 to control Tissue-Specific Chromatin Remodeling during Development of the Epidermis”, Journal of Cell Biology, 2011 Sep;194(6):825-39. M.Y. Fessing, R. Atoyan, B. Shander, A.N. Mandrayev, V.V. Jr Botchkarev, K. Poterlowicz, Y. Peng, T. Efimova and V.A. Botchkarev “Bmp signaling induces cell-type specific changes in gene expression programs of human keratinocytes and fibroblasts”, Journal of Investigative Dermatology, 2010 Feb;130(2):398-404.