1993 - PhD Biochemistry, University of Birmingham 1990 - BA Natural Sciences, University of Cambridge 2006-2014 Senior Lecturer in Molecular Oncology, University of Surrey 2000-2006 Lecturer in Cell and Developmental Biology, St. George's, University of London 1997-2000 Postdoctoral Scientist, Hubrecht Laboratory for Developmental Biology, Utrecht, The Netherlands 1993-1997 Postdoctoral Scientist, MRC National Institute for Medical Research, London

Oncology, Cancer biology, Biomarkers, Drug development, Transcription

Cancer, Transcription, Drug discovery, HOX genes, EN2, Biomarker

Kelly Z, Morgan R, Pandha H, Michael A. The prognostic significance of HOX genes in ovarian cancer. International Journal of Cancer. 2016 In press El-Tanani M, Dakir EH, Raynor B, Morgan R. Mechanisms of Nuclear Export in Cancer and Resistance to Chemotherapy. Cancers. 2016 Mar 14;8(3). pii:E35. Review. PubMed PMID: 26985906 Morgan R, El-Tanani M. HOX genes as potential markers of circulating tumor cells. Current Molecular Medicine 2016 16(4) :322-327 PubMed PMID: 26980702 Morgan R, Harrington K, Simpson GR, Gillett C, Tabi Z, Spicer J, Michael A, Pandha HS. HOX transcription factors are potential therapeutic targets in malignant mesothelioma. BMC Cancer 2016;16:85 Platais C, Hakami F, Darda L, Lambert DW, Morgan R, Hunter KD. The role of HOX genes in head and neck squamous cell carcinoma. J Oral Pathol Med. 2015 Dec 14.doi: 10.1111/jop.12388. Review. PubMed PMID: 26661059 McGrath SE, Michael A, Morgan R, Pandha H. EN2 in Prostate Cancer. Adv Clin Chem. 2015;71:47-76. doi:0.1016/bs.acc.2015.06.002. PubMed PMID: 26411411 De Paoli M, Perco P, Mühlberger I, Lukas A, Pandha H, Morgan R, Feng GJ, Marquette C. Disease map-based biomarker selection and pre-validation for bladder cancer diagnostics. Biomarkers. 2015 Jul 31:1-10. [Epub ahead of print] PubMed PMID: 26227542 Darda L, Hakami F, Morgan R, Murdoch C, Lambert DW, Hunter KD. The role of HOXB9 and miR-196a in Head and Neck Squamous Cell Carcinoma. PLoS One. 2015 10(4):e0122285. doi: 10.1371/journal.pone.0122285 Morgan R, Boxall A, Harrington K, Waters V, Simpson G, Michael A, Pandha HS. Targeting HOX transcription factors in prostate cancer. BMC Urol. 2014 Feb 5;14(1):17 Ando H, Natsume A, Senga T, Watanabe R, Ito I, Ohno M, Iwami K, Ohka F, Motomura K, Saito K, Morgan R, Wakabayashi T. Peptide-based inhibition of the HOXA9/PBX interaction retards the growth of human meningioma. Cancer Chemother Pharmacol. 2014 Jan;73(1):53-60 Killick E, Morgan R, Launchbury F, Bancroft E, Page E, Castro E, Kote-Jarai Z,Aprikian A, Blanco I, Clowes V, Domchek S, Douglas F, Eccles D, Evans DG, Harris M, Kirk J, Lam J, Lindeman G, Mitchell G, Pachter N, Selkirk C, Tucker K, Zgajnar J, Eeles R, Pandha H. Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk men. Sci Rep. 2013; 3:2059. doi: 10.1038/srep02059 McGrath SE, Michael A, Pandha H, Morgan R. Engrailed homeobox transcription factors as potential markers and targets in cancer. FEBS Lett. 2013 Mar 18;587(6):549-54 Errico MC, Felicetti F, Bottero L, Mattia G, Boe A, Felli N, Petrini M, Bellenghi M, Pandha HS, Calvaruso M, Tripodo C, Colombo MP, Morgan R, Caré A. The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway. Int J Cancer. 2013 Aug 15;133(4):879-92 Morgan R, Bryan R, Javed S, Launchbury F, Zeegers MP, Cheng KK, James ND, Wallace DMA, Hurst CD, Ward DG , Knowles MA, Pandha HS. Expression of Engrailed-2(EN2) protein in bladder cancer and its potential utility as a urinary diagnostic biomarker. European Journal of Cancer. 2013 Jun; 49(9):2214-22 Li Z, Zhang Z, Li Y, Chen P, Arnovitz S, Huang A, Jiang X, He C, Dohner K, Neilly MB, Wang C-Z, Bullinger L, Valk PJM, Delwel R, Lowenberg R, Morgan R, Yuan C, Rowley JD, Chen J. The HOXA/PBX3 axis is a prognostic biomarker and druggable target in cytogenetically abnormal acute myeloid leukaemia. Blood 2013 Feb 21;121(8):1422-31 Morgan R, Boxall A, Harrington K, Simpson GR, Michael A, Pandha HS. Targeting the HOX / PBX dimer in breast cancer. Breast Cancer Research and Treatment 2012, 136: 389-398 Alharbi R, Pettengell R, Pandha HS, Morgan R. The role of HOX genes in normal hematopoiesis and acute leukaemia. Leukemia 2013; 27:1000-8