PhD Thesis in Pharmacy, University of Lisbon, Portugal ( Nov 2006) PhD studies, University of Coimbra, Coimbra, Portugal/University of Kyushu, Fukuoka, Japan (2002-2006) PGDipPharm, Faculty of Pharmacy, University of Coimbra, Portugal (2000) Senior Post-Doctoral Fellow, Institute of Cancer Therapeutics, University of Bradford, England (2014-present) Research Associate, Radiopharmaceutical Science Group, Campus Technologic and Nuclear, Portugal (2009-2014) Post-Doctoral Research Assistant, Institute of Cancer Therapeutics, University of Bradford, England (2006-2009) Staff Pharmacist at the Community Pharmacy “Vasco da Gama”, Portugal (2001-2002)

I have been working at the interface of chemistry and biology and have developed skills ranging from Organic Chemistry, Medicinal Chemistry, Radiochemistry and Molecular Imaging. In Oct 2014, I returned to the ICT as Post-Doc to support the organic synthesis requirements across the Yorkshire Cancer Research Medicines Discovery programme. Precisely, I am participating in the: Development of duocarmycin synthetic derivatives as CYPs activated prodrugs Development of small molecule polysialyltransferase inhibitors as potential anti-metastatic agents

Medicinal Chemistry, Organic Chemistry, Molecular Imaging

Ribeiro Morais G, Springett BR, Pauze M, Schroeder L, Northrop M, Falconer RA "Novel strategies for the synthesis of unsymmetrical glycosyl disulfides" Org Biomol Chem 2016, 14, 2749 - 2754 Ribeiro Morais G, Palma E, Marques F, Gano L, Oliveira MC, Abrunhosa A, Miranda HV, Outeiro TF, Santos I, Paulo A "Synthesis and Biological Evaluation of Novel 2-Aryl Benzimidazoles as Chemotherapeutics Agents" J Heterocyclic Chem, 2016 accepted doi: 10.1002/jhet.2575 Nunes P, Ribeiro Morais G, Palma E, Silva F, Oliveira MC, Ferreira VFC, Mendes F, Gano L, Miranda H V, Outeiro TF, Santos I, Paulo A "Isostructural Re(I)/99mTc(I) Tricarbonyl Complexes Functionalized with Benzothiazole Derivatives for Cancer Theranostic" Org Biomol Chem 2015 13: 5182 Gill J, Loadman P, Shnyder S, Cooper P, Atkinson J, Ribeiro Morais G, Patterson L, Falconer RA "The Tumor-Targeted Prodrug ICT2588 Demonstrates Therapeutic Activity Against Solid Tumors and Reduced Potential For Cardiovascular Toxicity" Molecular Pharmaceutics, 2014 11(4): 1294-1300 Al-Saraireh Y M J, Sutherland M, Springett B R, Ribeiro Morais G, Loadman P M, Errington T J, Smith P J, Patterson L H, Shnyder S D, Falconer R A "Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration" Plos One 2013, 8(8):e73366 Ribeiro Morais G, Kniess T, Bergmann R, Gano L, Abrunhosa A, Santos I, Paulo A "Radiosynthesis and in vivo Evaluation of a 18F-Labelled Styryl-Benzoxazole Derivative for beta-Amyloid Targeting" Appl Rad Isotopes 2013, 82, 100-104 Ribeiro Morais G, Falconer R A; Santos I "Carbohydrate-based molecules suitable for nuclear molecular imaging" Eur J Org Chem 2013, 1401-1414 (Cover Picture) Oliveira M C, Neto C, Ribeiro Morais G, Thiemann T "Steroid receptor ligands for breast cancer targeting: an insight into their potential role as PET imaging agents" Curr Med Chem, 2013 20 (2), 222-245 Ribeiro Morais G, Santos I C, Santos I, Paulo A "X-ray diffraction structures of regioisomers of N-methylated benzimidazole compounds with interest for the synthesis of amyloid probes" J Chem Crystallogr 2012, 42, 1052-1059 Ribeiro Morais G, Paulo A, Santos I "Organometallic complexes for SPECT Imaging and/or Radionuclide Therapy" Organometallics 2012, 31, 5693-5714 Ribeiro Morais G, Paulo A, Santos I "A synthetic overview of radiolabeled compounds for β-amyloid targeting" Eur J Org Chem, 2012, 1279-1293 (Cover Picture) Ribeiro Morais G, Miranda H V, Santos I C, Santos I, Outeiro T F, Paulo A, "Synthesis and in vitro evaluation of fluorinated styryl benzazoles as amyloid-probes" Bioorg Med Chem, 2011, 19, 7698-7710 Ribeiro Morais G, Felix Oliveira I, Humphrey A J, Falconer R A "Identification of an acetyl disulfide derivative in the synthesis of thiosialosides." Carbohyd. Res, 2010, 345, 160-162