BSc Biochemistry and Pharmacology, University of Strathclyde (1986) PhD Medical Biochemistry, University of Glasgow (1991) PGDip Business Management, University of Bradford (2012) Bradford Leader; Strategic strand Postdoctoral researcher, funded by Wellcome Trust (1991-1994) British Heart Foundation (1994-1996) Lecturer in Biochemistry, University of Bradford (1996-2003)

Endothelial cell function in health and disease (atherosclerosis, diabetes, psoriasis) Epigenetic regulation of vascular cell function Mechanisms of angiogenesis Vascular cell dysfunction in diabetes and chronic kidney disease.

Endothelial cells; cell signalling; diabetes; cardiovascular disease; MAP kinase; angiogenesis; lymphoma

Sultan S, Liu W, Peng YH, Roberts W, Whitelaw D, Graham AM (2015) The role of maternal gestational diabetes in inducing fetal endothelial dysfunction Journal of Cellular Physiology 230, 2695-2705 Fhu CW, Graham AM, Yap CT, Al-Salam S, Castella A, Chong SM, Lim YC (2014) Reed Sternberg cell-derived lymphotoxin-α activates endothelial cells to enhance T cell recruitment in classical Hodgkin lymphoma. Blood. 2014 Aug 19. pii: blood-2014-05-576140 Banga NR, Prasad KR, Homer-Vanniasinkam S, Graham A (2012) An in vitro model of warm hypoxia-repoxygenation injury in human liver endothelial cells J Surg Res Epub PMID: 22472696 Alkhoury K, Homer Vanniasinkam S, Parkin SM, Graham AM (2011) Chronic homocysteine exposure upregulates endothelial adhesion molecules and mediates leukocyte:endothelial cell interactions under flow conditions EJVES 41, 429-435 Ghaderian HSM, Lindsey NJ, Graham AM, Najar RA (2010) Pathogenic mechanisms in varicose vein disease: the role of hypoxia and inflammation. Pathology 42, 446-453 Eccles KA, Porter K, Homer-Vanniasinkam S, Graham AM. (2008) Anti-inflammatory effects of statins on human endothelial cells. Atherosclerosis 200(1):69-79 Oberprieler NG, Roberts W, Riba R, Graham AM, Homer-Vanniasinkam S, Naseem KM (2007) cGMP-independent inhibition of integrin alphaIIb beta3-mediated platelet adhesion and outside-in signalling by nitric oxide. FEBS Letters 581, 1529-34 Oberprieler NG, Roberts W, Graham AM, Homer-Vanniasinkam S, Naseem KM (2007) Inhibition of ADP-induced platelet adhesion to immobilized fibrinogen by nitric oxide: Evicdence for cGMP independent mechanisms. Biochem Pharmacol 73, 1593-601 Gomez D, Homer-Vanniasinkam S, Graham AM, Prasad R (2007) Role of ischaemic preconditioning in liver regeneration following major liver resection and transplantation. World J Gastroenterol 13, 657-670