PhD, The School of Pharmacy, University of London (2000) BPharm(Hons), The School of Pharmacy, University of London (1996) MRPharmS, Pre-registration pharmacy training: Dartford & Gravesham NHS Trust (1997) Institute of Cancer Therapeutics, University of Bradford (2005-present) Lecturer in Pharmaceutical Sciences; The School of Pharmacy, University of London (2003-2005) Teaching and Research Fellow; The School of Pharmacy, University of London (2000-2003) Locum Pharmacist; Dartford & Gravesham NHS Trust (1997-2000) Staff Pharmacist; Dartford & Gravesham NHS Trust (1997)

Cancer Drug Discovery; Medicinal Chemistry; the tumour cell glycocalyx as a therapeutic target; Endoprotease-activated anti-tumour agents

Elkashef, S.M.; Allison, S.J.; Sadiq, M.; Basheer, H.A.; Ribeiro Morais, G.; Loadman, P.M.; Pors, K.; Falconer, R.A. “Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment.” Scientific Reports, 2016, 6, 33026 Elkashef, S.M.; Sutherland, M.; Patterson, L.H.; Loadman, P.M.; Falconer, R.A. “An optimised assay for quantitative, high-throughput analysis of polysialyltransferase activity.” Analyst, 2016, accepted Hussain, N.; Connah, D.; Ugail, H.; Cooper, P.A.; Falconer, R.A.; Patterson, L.H. and Shnyder, S.D. “The use of thermographic imaging to evaluate therapeutic response in human tumour xenograft models.” Scientific Reports, 2016, 6, 31136 Ribeiro Morais, G.; Springett, B.R.; Pauze, M.; Schroeder, L.; Northrop, M.; Falconer, R.A. "Novel strategies for the synthesis of unsymmetrical glycosyl disulfides" Organic and Biomolecular Chemistry, 2016, 14, 2749-2754 Grant, C.A.; Twigg, P.C.; Saeed, R.F.; Lawson, G.; Falconer, R.A.; Shnyder S.D. "The Effect of Polysialic Acid Expression on Glioma Cell Nano-mechanics." BioNanoScience, 2016, 6; 81-84 Gill, J.H.; Loadman, P.M.; Shnyder, S.D.; Cooper, P.A.; Atkinson, J.M.; Ribeiro Morais, G.; Patterson, L.H.; Falconer, R.A. “The Tumor-Targeted Prodrug ICT2588 Demonstrates Therapeutic Activity Against Solid Tumors and Reduced Potential For Cardiovascular Toxicity.” Molecular Pharmaceutics, 2014, 11, 1294?1300 Ansari, C.; Tikhomirov, G.A.; Hong, S.H.; Falconer, R.A.; Loadman, P.M.; Gill, J.H.; Castaneda, R.; Hazard, F.K.; Tong, L.; Felsher, D.W.; Rao, J.; Daldrup-Link, H.E. “Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy.” Small, 2014, 10, 566-575 (front cover p 474) Al-Saraireh, Y.M.J.; Sutherland, M.; Springett, B.R.; Freiberger, F.; Ribeiro Morais, G.; Loadman, P.M.; Errington, R.J.; Smith, P.J.; Fukuda, M.; Gerardy-Schahn, R.; Patterson, L.H.; Shnyder, S.D.; Falconer, R.A. “Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration.” PLoS ONE, 2013, 8, e73366 (open access: click here) Smith, P.J.; Falconer R.A.; Errington, R.J. “Micro-community cytometry: sensing changes in cell health and glycoconjugate expression by imaging and flow cytometry.” Journal of Microscopy, 2013, 251, 113-122 Smith, P.J.; Wiltshire, M.; Chappell, S.; Patterson, L.H.; Shnyder, S.D.; Falconer, R.A.; Errington, R.J. “Profiling dynamic changes NCAM polysialylation during adherence transitions of live cells using an antibody-mimetic eGFP-endosialidase and the viability dye DRAQ7.” Cytometry Part A, 2013, 83, 659-671 Ribeiro Morais, G.; Falconer, R.A.; Santos, I. “Carbohydrate-based molecules for Molecular Imaging in Nuclear Medicine.” European Journal of Organic Chemistry, 2013, 8, 1401-14 Fournier Dit Chabert, J.; Vinader, V.; Santos, A.; Redondo-Horcajo, M.; Dreneau, A.; Basak, R.; Cosentino, L.; Gordon, A.; Abdel-Rahman, H.; Loadman, P.M.; Shnyder, S.D.; Fernando Díaz, F.; Barasoain, I.; Falconer, R.A.; Pors, K. “Synthesis and Biological Evaluation of Colchicine C-Ring Analogues Tethered with Aliphatic Linkers Suitable for Prodrug Derivatisation.” Bioorganic and Medicinal Chemistry Letters, 2012, 22, 7693-7696 Falconer, R.A.; Errington, R.J.; Shnyder, S.D.; Smith, P.J.; Patterson, L.H. “Polysialyltransferase: a new target in metastatic cancer.” Current Cancer Drug Targets, 2012, 12, 925-939 Kong, F.; Ribeiro Morais, G.; Falconer, R.A.; Sutton, C.W. “An optimized method for the synthesis of amino functionalized phosphatidylcholine.” Tetrahedron Letters, 2012, 53, 546-549