Cooper, Helen J.
Professor
所属大学: University of Birmingham
所属学院: School of Biosciences
个人简介
Professor Helen J. Cooper obtained her BSc and PhD in Chemistry at the University of Warwick. She began her post-doctoral career at the University of Warwick, before taking a faculty position at the National High Magnetic Field Laboratory, Florida State University, in 2000. In 2003, she returned to the UK as Wellcome Trust Value-in-People Fellow at the University of Birmingham.She was subsequently awarded a Wellcome Trust University Technology Fellowship to develop high performance mass spectrometry methods for use in biomedical research. In 2010, she took up the post of Senior Lecturer.
近期论文
‘Dissociation techniques in mass spectrometry-based proteomics’ Jones, A.W.; Cooper, H.J. The Analyst, 2011, in press. ‘Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production’ Hothersall, J.; Murphy, A.C.; Iqbal,, Z., Campbell, G.; Stephens, E.R.; Wu, J.; Cooper, H.J.; Atkinson, S.; Williams, P.; Crosby, J.; Willis, C.L.; Cox, R.J.; Simpson, T.J.; Thomas, C.M. Appl. Microbiol. Biotech., 2011, in press ‘Haemoglobin variant analysis (HbS, HbC and HbD) via direct surface sampling of dried blood spots coupled with high resolution mass spectrometry’ Edwards, R.L.; Creese, A.J.; Baumert, M.; Griffiths, P.; Bunch, J.; Cooper, H.J. Anal. Chem., 2011, 83, 2265-2270. ‘Novel glycosylation sites localized in Campylobacter jejuni flagellin FlaA by liquid chromatography electron capture dissociation tandem mass spectrometry’ Zampronio, C.G.; Blackwell, G.; Penn, C.W.; Cooper, H.J. J. Proteome Res., 2011, 10, 1238-1245. ‘Complete separation of peptide isomers with variant modified sites by high-resolution differential ion mobility spectrometry’ Shvartsburg, A.A.; Creese, A.J.; Smith, R.D.; Cooper, H.J. Anal. Chem., 2010, 82, 8327-8334. ‘On-line liquid chromatography neutral loss-triggered electron transfer dissociation mass spectrometry for the targeted analysis of citrullinated peptides’ Creese, A.J.; Grant, M.M.; Chapple, I.L.C.; Cooper, H.J. Anal. Methods, 2011, 3, 259-266. ‘Electron induced dissociation (EID) tandem mass spectrometry of octaethylporphyrin and its iron (III) complex’ Kaczorowska, M.A.; Cooper, H.J. Chem. Commun., 2011, 47, 418-420. ‘Probing the mechanisms of electron capture dissociation mass spectrometry with nitrated peptides’ Jones, A.W.; Cooper, H.J. Phys. Chem. Chem. Phys., 2010, 12, 13394-13399. ‘Proteomic analysis of a non-invasive human model of acute inflammation and its resolution: the 21 day gingivitis model’ Grant, M.M.; Creese, A.J.; Barr, G.; Ling, M.; Matthews, J.B.; Griffiths, H.R.; Cooper, H.J.; Chapple, I.L.C. J. Proteome Res., 2010, 9, 4732-4744. ‘Top-Down Mass Analysis of Protein Tyrosine Nitration: Comparison of Electron Capture Dissociation with ‘Slow-Heating’ Tandem Mass Spectrometry Methods’ Mikhailov, V.A.; Iniesta, J.; Cooper, H.J. Anal. Chem., 2010, 82, 7283-7292. ‘Nitration of lysozyme by ultrasonic waves: Demonstration by immunochemistry and mass spectrometry’ Dean, S.; Cox, M.; Heptinstall, J.; Walton, D.J.; Mikhailov, V.A.; Cooper, H.J.; Gomez-Mingot, M.; Iniesta, J. Ultrasonics Sonochemistry, 2011, 18, 334-344. ‘Can museum egg specimens be used for proteomic analyses?’ Portugal, S.J.; Cooper, H.J.; Zampronio, C.G.; Wallace, L.L.; Cassey, P. Proteome Science, 2010, 8, 40. ‘Electron induced dissociation: A mass spectrometry technique for the structural analysis of trinuclear oxo-centred carboxylate-bridged iron complexes’ Kaczorowska, M.A.; Cooper, H.J. J. Am. Soc. Mass Spectrom., 2010, 21, 1398-1403. ‘Differential phosphoproteomics of fibroblast growth factor signalling: Identification of Src family kinase-mediated phosphorylation events’ Cunningham, D.L.; Sweet, S.M.M.; Cooper, H.J.; Heath, J.K. J. Proteome Res., 2010, 9, 2317-2328. ‘Retention of enzyme activity with a boron doped diamond electrode in the electro-oxidative nitration of lysozyme’ Iniesta, J.; Deseada Esclapez-Vicente, M.; Heptinstall, J.; Walton, D.J.; Peterson, I.R.; Mikhailov, V.A.; Cooper, H.J. Enzyme and Microbial Technology ,2010, 46, 472-478. ‘Electron capture dissociation mass spectrometry of metallo-supramolecular complexes’ Kaczorowska, M.A.; Hotze, A.C.G.; Hannon, M.J.; Cooper, H.J. J. Am. Soc. Mass Spectrom., 2010, 21, 300-309. ‘Electron capture dissociation mass spectrometry of tyrosine nitrated peptides’ Jones, A.W.; Mikhailov, V.A.; Iniesta, J.; Cooper, H.J. J. Am. Soc. Mass Spectrom., 2010, 21, 268-277. ‘Database search strategies for proteomic datasets generated by electron capture dissociation mass spectrometry’ Sweet, S.M.M.; Jones, A.W.; Cunningham, D.L.; Heath, J.K.; Creese, A.J.; Cooper, H.J. J. Proteome Res., 2009, 8, 5475-5484. ‘Characterization of polyphosphoesters by Fourier transform ion cyclotron resonance mass spectrometry’ Kaczorowska, M.A.; Cooper, H.J. J. Am. Mass Spectrom., 2009, 20, 2238-2247. ‘Hot electron capture dissociation distinguishes leucine from isoleucine in a novel hemoglobin variant, Hb Askew, β54(D5)Val?Ile’ Williams, J.P.; Creese, A.J.; Roper, D.R.; Green, B. N.; Cooper, H.J. J. Am. Soc. Mass Spectrom. 2009, 20, 1707-1713.