Wang, Wenxin 照片

Wang, Wenxin

Professor

所属大学: University College of Dublin

所属学院: School of Medicine

邮箱:
wenxin.wang@ucd.ie

个人主页:
http://www.wenxinwang.group/

个人简介

Current Employment: 2019-present Senior Conway Fellow, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD), Dublin, Ireland 2018-present Guest Professor, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China 2018-present Adjunct Professor, School of Mechanical and Materials Engineering, University College Dublin (UCD), Dublin, Ireland 2018-present Professor, Charles Institute of Dermatology, School of Medicine, University College Dublin (UCD), Dublin, Ireland 2018-present Founder & Chairman & CSO, Blafar Ltd. 2019-present Founder & Chairman, Branca Bunús Ltd. 2011-present Science Foundation Ireland (SFI) Principal Investigator, Ph.D., FRSC (Fellow of The Royal Society of Chemistry) Previous Employment: 2013-2018 Associate Professor, Charles Institute of Dermatology, School of Medicine, University College Dublin (UCD), Dublin, Ireland 2010-2018 Founder & Chairman & CSO, Vornia Ltd. (purchased by Ashland Inc.) 11.2013 Professor in Synthetic/Polymer Chemistry, the Faculty of Science and Engineering, University of Wolverhampton, UK 2009-2013 Science Foundation Ireland (SFI) Stokes Lecturer in Functional Biomaterials, Network of Excellence for Functional Biomaterials (NFB), National Centre for Biomedical Engineering Science (NCBES), Department of Mechanical and Biomedical Engineering, College of Engineering & Informatics, National University of Ireland, Galway, (NUI Galway), Ireland 2008-2009 University Fellow (Teaching and Research) in Biomedical Engineering (Functional Biomaterials), NUI Galway, Ireland 2007-2008 Senior Research Fellow, Advanced Drug Delivery and Tissue Engineering Group, School of Pharmacy, the University of Nottingham, UK 2001-2006 Senior Research Fellow, Green Chemistry Group, School of Chemistry, the University of Nottingham, UK 2000-2001 Research Fellow, Centre for Education and Research on Macromolecules (CERM), University of Liege, Belgium

研究领域

The research interests in our group are mainly focused on: 1) mechanistic understanding of reversible deactivation radical polymerization (RDRP); 2) kinetically controlled (co)polymerization of multivinyl monomers (MVMs); 3) structural design and biomedical application of knotted/cyclized and branched polymers in skin wound healing and tissue regeneration. Our clinical targets are gene therapy of recessive dystrophic epidermolysis bullosa (RDEB), diabetic foot repair, cartilage regeneration and neural degenerative diseases. Specifically, our current research areas include: Mechanistic understanding of ATRP, RAFT and CU0-mediated RDRP (including experiment, theoretical calculation and computer simulation) Kinetically controlled (co)polymerization of MVMs Macromolecular design and engineering via RDRP techniques (ATRP, RAFT, CU0-mediated RDRP, ROP and anionic polymerisation) and click chemistry Multifunctional cyclized/knotted and branched polymers as gene delivery vectors Injectable extracellular matrix (ECM) biopolymer hybrid hydrogels for stem cells encapsulation and drug delivery Bio-inspired responsive polymers as tissue adhesives

近期论文

Mousavizadeh, S., He, Z., Wang, X., Shen, P., Wang, W., Gilchrist, M., Zhang, N.*, ‘Surface modification of WE43 magnesium alloy via alkali/stearic acid treatment for biodegradable drug-eluting stent applications’. MATERIALS CHEMISTRY AND PHYSICS, 2023, DOI: 10.1016/j.matchemphys.2023.128249. Li, Y., He, Z., Sigen, A., Wang, X., Li, Z., Johnson, M., Foley, R., Lara-Sáez, I., Lyu, J.*, Wang, W.*, ‘Artificial Intelligence (AI)-aided Structure Optimization for Enhanced Gene Delivery: The Effect of Polymer Component Distribution (PCD)’. ACS APPLIED MATERIALS & INTERFACES, 2023, DOI: 10.1021/acsami.3c05010. Li, Y., Wang, X., He, Z., Johnson, M., Sigen, A., Lara-Sáez, I., Lyu, J.*, Wang, W.*, ‘3D Macrocyclic Structure Boosted Gene Delivery: Multi-cyclic Poly(β-Amino Ester)s from Step Growth Polymerization’. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, DOI: 10.1021/jacs.3c04191. Li, Z., Lyu, J.*, Li, Y., Qiu, B., Johnson, M, Tai, H., Wang, W.*, ‘Controlled Polymerization of Acrylamide via One-Pot and One-Step Aqueous Cu (0)-Mediated Reversible-Deactivation Radical Polymerization’. MACROMOLECULES, 2023, DOI: 10.1021/acs.macromol.3c00343. Lyu, J., Miao, Y., Li, Z., Li, Y.,Gao, Y., Johnson, M, Tai, H., Wang, W.*, ‘Where is the induction from? Effect of disproportionation and comproportionation in Cu (0)-mediated reversible deactivation radical polymerization’. POLYMER, 2023, DOI: 10.1016/j.polymer.2023.126055. Jagannath, A., Li, Y., Cong, H., Hassan, J., Gonzalez, G., Wang, W., Zhang, N.*, and Gilchrist, M.* ‘UV-Assisted Hyperbranched Poly(β-amino ester) Modification of a Silica Membrane for Two-Step Microfluidic DNA Extraction from Blood’. ACS APPLIED MATERIALS & INTERFACES, 2023, DOI: 10.1021/acsami.3c03523. Li, Y., He, Z., Wang, X., Li, Z., Johnson, M., Foley, R., Sigen, A., Lyu, J.*, Wang, W.*, ‘Branch Unit Distribution Matters for Gene Delivery’. ACS MACRO LETTERS, 2023, DOI: 10.1021/acsmacrolett.3c00152. (Cover image) Wang, X., Song, R., Johnson, M., A, S., Shen, P., Zhang, N., Lara-Sáez, I., Xu, Q., Wang, W.*, ‘Chitosan-based hydrogels for infected wound treatment’. MACROMOLECULAR BIOSCIENCE, 2023, DOI: 10.1002/mabi.202300094. Zhang, J., He, Z., Li, Y., Shen, Y., Wu, G., Power, L., Song, R., Zeng, M., Wang, X., Lara-Sáez, I., A. S., Xu, Q., Curtin, J., Yu, Z.*, Wang, W.*, ‘Enhanced gene transfection efficacy and safety through granular hydrogel mediated gene delivery process’. ACTA BIOMATERIALIA, 2023, 15, 1518, DOI: 10.1016/j.actbio.2023.04.041. Li, Y., Wang, X., He, Z., Li, Z., Johnson, M., Qiu, B., Song, R., A, S., Lara-Sáez, I., Lyu, J.*,Wang, W.*, ‘A New Optimization Strategy of Highly Branched Poly(β-Amino Ester) for Enhanced Gene Delivery: Removal of Small Molecular Weight Components’. POLYMERS, 2023, 15, 1518, DOI: 10.3390/polym15061518. Wang, X., Zhou, Y., Johnson, M., Milne, C., A, S., Li, Y., Wang, W., Zhang, N.*, Xu, Q.*, ‘A Novel Hydrophilic, Antibacterial Chitosan-Based Coating Prepared by Ultrasonic Atomization Assisted LbL Assembly Technique’. JOURNAL OF FUNCTIONAL BIOMATERIALS, 2023, 14, 43, DOI: 10.3390/jfb14010043. Lyu, J., Li, Y., Li, Z., Polanowski, P., Jeszka, J., Matyjaszewski, K., Wang, W.*, ‘Modelling Development in Radical (Co)Polymerization of Multivinyl Monomers’. ANGEWANDTE CHEMIE, 2022, 62, 5, DOI: 10.1002/anie.202212235. Rodrigues, P., Wang, X., Li, Z., Lyu, J.*, Wang, W., Vieira., P.*, ‘A new nano hyperbranched β-pinene polymer: controlled synthesis and nonviral gene delivery’. COLLOIDS AND SURFACES B: BIOINTERFACES, 2022, 222, DOI: 10.1016/j.colsurfb.2022.113032. Li, Y., He, Z., Lyu, J., Wang, X., Qiu, B., Lara-Sáez, I., Zhang, J., Zeng, M., Xu, Q., A, S., Curtin, J.F.*, Wang, W.*, ‘Hyperbranched Poly(β-amino ester)s (HPAEs) Structure Optimisation for Enhanced Gene Delivery: Non-Ideal Termination Elimination’. NANOMATERIALS, 2022, 12, 3893, DOI: 10.3390/nano12213892. Zhou, Y., Wang, X., Li, Y., Wang, W.*, Michael G., Zhang, N.*, ‘Towards the scalable fabrication of fully bio-based antimicrobial and UVB-blocking transparent polylactic acid films that incorporate natural coatings and nanopatterns’. ACS APPLIED MATERIALS & INTERFACES, 2022, in press, DOI: 10.1021/acsami.2c15416. Lin, J., Xu, Q., Liu, Z., Zhao, C., Tang, J., Han, J., A, S., Wang, W., Zhuo, Y., Li, Y.*, ‘In situ-crosslinked hydrogel-induced experimental glaucoma model with persistent ocular hypertension and neurodegeneration’. BIOMATERIALS SCIENC, 2022, 10, 5006, DOI: 10.1039/D2BM00552B. Gunes, S., He, Z., Tsoukou, E., Ng, S., Boehm, D., Lopes, B, P., Bourke, P., Malone, R., Cullen, P, J., Wang, W., Curtin, James.*, ‘Cell death induced in Glioblastoma cells by Plasma-Activated-Liquids (PAL) is primarily mediated by membrane lipid peroxidation and not ROS influx’. PLOS ONE, 2022, 17, 9, DOI: 10.1371/journal.pone.0274524. Wang, C., Sun, L., Li, Q., Li, Z., Xu, C., Zhang, X., Shi, J.*, Zhou, H.*, Wang, W., Zhou, D.*, ‘Highly branched poly(β-amino ester)s with narrow molecular weight distribution: Fractionation and gene transfection activity’. CHINESE CHEMICAL LETTERS, 2022, DOI: 10.1016/j.cclet.2022.06.050. Zhang, W., Zhang, Q., Yang, N., Shi, Q., Su H, Lin, T., He, Z., Wang, W., Guo, H.*, Shen, P.*, ‘Crosstalk between IL-15Rα+ tumor-associated macrophages and breast cancer cells reduces CD8+ T cell recruitment’. CANCER COMMUN, 2022, 1-22, DOI: 10.1002/cac2.12311. Azhari, Z., Smith, P., McMahon, S., Wang, W., Cameron, Ruth E.*, ‘Modulating Drug Release from Short Poly(ethylene glycol) Block Initiated Poly(L-lactide) Di-block Copolymers’. PHARM RES (2022), 2022, DOI: 10.1007/s11095-022-03228-8. Sun, L., Wang, J., Wang, Q., He, Z., Sun, T., Yao, Y., Wang, W., Shen, P.*, ‘Pretreatment of umbilical cord derived MSCs with IFN-γ and TNF-α enhances the tumor-suppressive effect on acute myeloid leukemia’. BIOCHEM. PHARMACOL, 2022, 199, 115007, DOI: 10.1016/j.bcp.2022.115007. Newland, B.*, Starke, J., Bastiancich, C., Gonçalves, D.P.N., Bray, L.J., Wang, W., Werner, C., ‘Well-Defined Polyethylene Glycol Microscale Hydrogel Blocks Containing Gold Nanorods for Dual Photothermal and Chemotherapeutic Therapy’. PHARMACEUTICS, 2022, 14, 551, DOI: 10.3390/pharmaceutics14030551. Wang, C., Huang, X., Sun, L., Li, Q., Li, Z., Young, H., Che, D., Yan, C., Geng, S., Wang, W.*, Zhou, D.*, ‘Cyclic poly(β-amino ester)s with enhanced gene transfection activity synthesized through intra-molecular cyclization’. CHEM. COMMUN., 2022, 58, 2136, DOI: 10.1039/d1cc06480k. Wang, X., Alshehri, F., Manzanares, D., Li, Y., He, Z., Qiu, B., Zeng, M., A, S., Lara-Sáez, I.,* Wang, W.*, ‘Development of Minicircle Vectors Encoding COL7A1 Gene with Human Promoters for Non-Viral Gene Therapy for Recessive Dystrophic Epidermolysis Bullosa’. INT.J.MOL.SCI, 2021, 22, 12774, DOI: 10.3390/ijms222312774. Yu,D., Huang, J., Zhang, Z., Weng, J., Xu, X., Zhang, G., Zhang, J., Wu,X.,* Johnson, M., Lyu, J.,* Yang,H., Wang, W.*, ‘Simultaneous realization of superoleophobicity and strong substrate adhesion in water via a unique segment orientation mechanism’. ADVANCED MATERIALS, 2021, 2106908, DOI: 10.1002/adma.202106908. Koivuniemi, R.*, Xu, Q.*, Snirvi, J., Lara-Saez, I., Merivaara, A., Luukko, K., Nuopponen, M., Wang, W.*, Yliperttula, M., ‘Comparison of the Therapeutic Effects of Native and Anionic Nanofibrillar Cellulose Hydrogels for Full Thickness Skin Wound Healing’. MICRO, 2021, 1(2), 194-214, DOI: 10.3390/micro1020015. Vasquez,J., Idrees, D., Carmagnola, I., A, S., McMahon, S., Marlinghaus,L., Ciardelli, G., Greiser,U., Tai,H., Wang, W., Salber,J.,Chiono,V., ‘In situ forming hyperbranched PEG - thiolated hyaluronic acid hydrogels with honey-mimetic antibacterial properties’. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, SECTION BIOMATERIALS, 2021, 9, DOI: 10.3389/fbioe.2021.742135. Wang, X., Song, R., Johnson, M., A, S., He, Z., Milne, C., Wang X., Lara-Saez, I., Xu, Q.*, Wang, W.*, ‘An injectable Chitosan-based self-healable hydrogel system as an antibacterial wound dressing’. MATERIALS, 2021, 14(20), 5956, DOI: 10.3390/ma14205956. Wang, X., Li, X., Duffy, P., McMahon, S., Wang, X., Lyu, J., Xu, Q.*, A, S., Chen, N., Bi, V., Dürig, T., Wang, W.*, ‘Resveratrol-Loaded PLGA Microspheres Integrated in An HA Injectable Hydrogel for Cartilage Regeneration’. ADVANCED NANOBIOMED RESEARCH, 2021, 2, 2100070, DOI: 10.1002/anbr.202100070. Gan, M., Zhou, Q., Ge, J., Zhao, J., Wang, Y., Yan, Q., Wu, C., Yu, H., Xiao, Q.,Wang, W., Yang, H., Zou, J.*, ‘Precise in-situ release of microRNA from an injectable hydrogel induces bone regeneration’. ACTA BIOMATERIALIA, 2021, 135, 289, DOI: 10.1016/j.actbio.2021.08.041. He,Z.*, Charleton, C., Devine, R., Kelada, M., Walsh, J., Conway, G., Gunes, S., Mondala, J., Tian, F., Tiwari, B., Kinsella, G., Malone, R., O’Shea, D., Devereux, M., Wang, W., Cullen, P., Stephens, J., Curtin, J.* ‘Enhanced pyrazolopyrimidinones cytotoxicity against glioblastoma cells activated by ROS-Generating cold atmospheric plasma’. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 224, 113736, DOI: 10.1016/j.ejmech.2021.113736. O'Keeffe Ahern, J., Lara-Saez, I.*, Zhou, D., Murillas, R., Bonafont, J., Mencía, Á.,García,M., Manzanares, D., Lynch, J., Foley,R., Xu, Q., Sigen, A., Larcher, F., Wang, W.*, ‘Non-viral delivery of CRISPR–Cas9 complexes for targeted gene editing via a polymer delivery system’. GENE THERAPY, 2021, DOI: 10.1038/s41434-021-00282-6. He, Z., Xu, Q., Newland, B., Foley, R., Lara-Saez, I., Curtin, J., Wang, W.* ‘Reactive Oxidative Species (ROS): Utilizing Injectable Antioxidative Hydrogels and ROS-Producing Therapies to Manage the Double-Edged Sword’. JOURNAL OF MATERIALS CHEMISTRY B, 2021, 9, 6326-6346, DOI: 10.1039/D1TB00728A. Zeng, M., Xu, Q., Zhou, D.*, A, S., Alshehri, F., Lara-Saez, I., Zheng Y., Li M.*, Wang, W.* ‘Highly Branched Poly(ß-amino ester)s for Gene Delivery in Hereditary Skin Diseases’. ADVANCED DRUG DELIVERY REVIEWS, 2021, 176, 113842, DOI: 10.1016/j.addr.2021.113842. Li, X., Xu, Q., Johnson, M., Wang X., Lyu, J., Li, Y., McMahon S., Greiser U., A, S.*, Wang, W.* ‘A Chondroitin Sulfate based Injectable Hydrogel for Delivery of Stem Cells in Cartilage Regeneration’. BIOMATERIALS SCIENCE, 2021, 9, 4139, DOI: 10.1039/d1bm00482d. Cai, Y., Johnson, M., A, S., Xu, Q.*, Tai, H., Wang, W.* ‘A Hybrid Injectable and Self-Healable Hydrogel System As 3D Cell Culture Scaffold’. MACROMOLECULAR BIOSCIENCE, 2021, 2100079, DOI: 10.1002/mabi.202100079. Newland, B.*, Newland, H., Lorenzi, F., Eigel, D., Welzel, P., Fischer, D., Wang, W., Freudenberg, U., Rosser, A., Werner, C. ‘Injectable Glycosaminoglycan Based Cryogels from Well-defined Microscale Templates for Local Growth Factor Delivery’. ACS CHEMICAL NEUROSCIENCE, 2021, 12(7), 1178-1188, DOI: 10.1021/acschemneuro.1c00005. A, S., Xu, Q.*, Johnson, M., Creagh-Flynn, J., Venet, M., Zhou, D., Lara-Saez, I., Tai, H., Wang, W.* ‘An Injectable Multi-Responsive Hydrogel as Self-Healable and On-demand Dissolution Tissue Adhesive’. APPLIED MATERIALS TODAY, 2021, 22, 100967, DOI: 10.1016/j.apmt.2021.100967. López-Cano, J., A, S., Andrés-Guerrero, V., Tai, H., Bravo-Osuna, I., Molina-Martínez, I., Wang, W., Herrero-Vanrell, R.* ‘Thermo-responsive PLGA-PEG-PLGA hydrogels as novel injectable platforms for neuroprotective combined therapies in the treatment of retinal degenerative diseases’. PHARMACEUTICS, 2021, 13(2), 234, DOI: 1999-4923/13/2/234. Orlando,I., Basnett, P., Nigmatullin, R., Wang, W., Knowles, J., Roy, I.* ‘Chemical modification of bacterial cellulose for the development of an antibacterial wound dressing’. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, SECTION NANOBIOTECHNOLOGY, 2020, 8, 557885, DOI: 10.3389/fbioe.2020.557885. Alghamdi, M., Chierchini, F., Eigel, D., Taplan, C., Miles, T., Pette, D., Welzel, P., Werner, C., Wang, W., Neto, C., Gumbleton M. and Newland, B.* ‘Poly(ethylene glycol) based nanotubes for tuneable drug delivery to glioblastoma multiforme’. NANOSCALE ADVANCES, 2020, 2, 4498-4509, DOI: 10.1039/D0NA00471E. Liu,T*, Li,X., Wang,T., Chen, M. , Zhang S., Liao, J., Wang, W., Zou, X. , Zhou,G.* ‘Kartogenin mediates cartilage regeneration by stimulating the IL-6/Stat3-dependent proliferation of cartilage stem/progenitor cells’. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 532, 3, 385-392, DOI: 10.1016/j.bbrc.2020.08.059. A, S., Lyu, J., Johnson, M., Creagh-Flynn, J., Zhou, D., Lara-Sez, I., Xu, Q.*, Tai, H., Wang, W.* ‘Instant Gelation System as Self-Healable and Printable 3D Cell Culture Bio-Ink based on Dynamic Covalent Chemistry’. ACS APPLIED MATERIALS & INTERFACES, 2020, 12, 38918–38924, DOI: 10.1021/acsami.0c08567. Pacharra, S., Mcmahon, S., Duffy, P., Basnett, P., Yu, W., Seisel, S., Stervbo, U., IpRoy, I., Viebahn, R., Wang, W., Salber, J.* ‘Cytocompatibility Evaluation of a Novel Series of PEG-Functionalized Lactide-Caprolactone Copolymer Biomaterials for Cardiovascular Applications’. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, SECTION BIOMATERIALS, 2020, 8, 991, DOI: 10.3389/fbioe.2020.00991. Li, X., A, S., Xu,Q., Alshehri, F., Zeng, M., Zhou, D., Li, J., Zhou, G., Wang, W.* ‘Cartilage-Derived Progenitor Cell-Laden Injectable Hydrogel—An Approach for Cartilage Tissue Regeneration’. ACS APPLIED BIO MATERIALS, 2020, 3, 4756–4765, DOI: 10.1021/acsabm.0c00294. A, S., Zeng, M., Johnson, M., Creagh-Flynn, J., Xu, Q.*, Tai, H., Wang, W.* ‘Green Synthetic Approach for Photo-Cross-Linkable Methacryloyl Hyaluronic Acid with a Tailored Substitution Degree’. BIOMACROMOLECULES, 2020, 21, 2229-2235, DOI: 10.1021/acs.biomac.0c00196. Wang, Y., Wang, C., Li, M., Zhou, D.*, Huang, W., Wang, W.* ‘Effects of Branching Strategy on the Gene Transfection of Highly Branched Poly(β-amino ester)s’. CHINESE JOURNAL OF POLYMER SCIENCE, 2020, 38, 830-839, DOI: 10.1007/s10118-020-2393-y. Gao, Y., Zhou, D.*, Lyu J., A, S., Xu, Q., Newland, B., Matyjaszewski, K., Tai, H., Wang, W.* ‘Complex polymer architectures through free-radical polymerization of multivinyl monomers’. NATURE REVIEWS CHEMISTRY, 2020, 4, 194-212, DOI: 10.1038/s41570-020-0170-7. Blackburn, C., Tai, H.*, Salerno, M., Wang, X., Senan, C., Ratcliffe, L, Hartsuiker, E., Wang, W.* ‘Data presenting the synthesis of three novel stimuli responsive hyperbranched polymers synthesised via RAFT polymerisation and the bio conjugation of folic acid’. DATA IN BRIEF, 2020, 28, 104861, DOI: 10.1016/j.dib.2019.104861. Xie, T., Ding, J., Han, X., Jia, H., Yang, Y., Liang, S., Wang, W., Liu, W.*, Wang, W.* ‘Wound Dressing Change Facilitated by Spraying Zinc Ions’. MATERIALS HORIZONS, 2020, 7, 605-614, DOI: 10.1039/C9MH01255A. Blackburn, C., Tai, H.*, Salerno, M., Wang, X., Hartsuiker, E., Wang, W.* ‘Folic acid and rhodamine labelled pH responsive hyperbranched polymers: Synthesis, characterization and cell uptake studies’. EUROPEAN POLYMER JOURNAL, 2019, 120, 109259, DOI: 10.1016/j.eurpolymj.2019.109259. Duffy, P., McMahon, S., Wang, X., Keaveney, S., O’Cearbhaill, E., Quintana, I., Rodríguez, F., Wang, W.* ‘Synthetic Bioresorbable Poly-α-hydroxyesters as Peripheral Nerve Guidance Conduits: A Review of Material Properties, Design Strategies and Their Efficacy to Date’. BIOMATERIALS SCIENCE, 2019, 7, 4912-4943, DOI: 10.1039/C9BM00246D. Zeng, M., Alshehri, F., Zhou, D.*, Lara-Sáez, I., Wang, X., Li, X., A, S., Xu, Q., Zhang, J., Wang, W.* ‘Efficient and Robust Highly Branched Poly(β-Amino Ester)/Minicircle COL7A1 Polymeric Nanoparticles for Gene delivery to Recessive Dystrophic Epidermolysis Bullosa Keratinocytes’. ACS APPLIED MATERIALS & INTERFACES, 2019, 11, 34, 30661-30672, DOI: 10.1021/acsami.9b13135. Liu, S., Gao, Y., Zhou, D.*, Zeng, M., Alshehri, F., Newland, B., Lyu, J., O'Keeffe-Ahern, J., Greiser, U., Guo, T.*, Zhang, F., Wang, W.* ‘Highly branched poly(β-amino ester) delivery of minicircle DNA for transfection of neurodegenerative disease related cells’. NATURE COMMUNICATIONS, 2019, 10, 3307, DOI: 10.1038/s41467-019-11190-0. Xu, Q., A, S., Venet, M., Gao, Y., Zhou, D.*, Wang, W., Zeng, M., Rotella, C., Li, X., Wang, X., Lyu, J., Rodriguez, B. J., Wang, W.* ‘Bacterial-Resistant Single Chain Cyclized/Knotted Polymer Coatings’. ANGEWANDTE CHEMIE, 2019, 131, 10726-10730, DOI: 10.1002/ange.201904818. Miao, Y., Lyu, J., Yong, H., A, S., Gao, Y.*, Wang, W.* ‘Controlled Polymerization of Methyl Methacrylate and Styrene via Cu(0)-Mediated RDRP by Selecting the Optimal Reaction Conditions’. CHINESE JOURNAL OF POLYMER SCIENCE, 2019, 37(6), 591-597, DOI: 10.1007/s10118-019-2236-x. Du, B., Fan, T., Li, J., Gong, L., Zhang, Q., Ye, W., Tai, H., Wang, W., Fan, Z.* ‘PLLA-Grafted Gelatin Amphiphilic Copolymer and Its Self-Assembled Nano Carrier for Anticancer Drug Delivery’. MACROMOLECULAR CHEMISTRY & PHYSICS, 2019, 220, 1800528, DOI: 10.1002/macp.201800528. Wang, W., Chen, J., Li, M., Jia, H., Han, X., Zhang, J., Zou, Y., Tan, B., Liang, W., Shang, Y., Xu, Q., A, S., Wang, W., Mao, J., Gao, X.*, Fan, G.*, Liu, W.* ‘Rebuilding Postinfarcted Cardiac Functions by Injecting TIIA@PDA Nanoparticle-Cross-Linked ROS-Sensitive Hydrogels’. ACS APPLIED MATERIALS & INTERFACES, 2019, 11(3), 2880-2890, DOI: 10.1021/acsami.8b20158. Zeng, M., Zhou, D.*, Alshehri, F., Lara-Sáez, I., Lyu, Y., Creagh-Flynn, J., Xu, Q., A, S., Zhang, J., Wang, W.* ‘Manipulation of Transgene Expression in Fibroblast Cells by a Multifunctional Linear-Branched Hybrid Poly(β-Amino Ester) Synthesized through an Oligomer Combination Approach’. NANO LETTERS, 2019, 19(1), 381-391, DOI: 10.1021/acs.nanolett.8b04098. Yong, H., Miao, Y., A, S.*, Quan, D., Ivankovic, A., Singh, K., Zhang, J., Zhou, D., Wang, W.* ‘Branched Polystyrenes from a Suspension “Strathclyde” Polymerization Using a Vulcanization Accelerator as Chain Transfer Agent’. POLYMER CHEMISTRY, 2019, 10, 885-890, DOI: 10.1039/C8PY01639A. Pacharra, S., Ortiz, R., McMahon, S., Wang, W., Viebahn, R., Salber, J.*, Quintana, I. 'Surface Patterning of a Novel PEG-Functionalized Poly-L-Lactide Polymer to Improve Its Biocompatibility: Applications to Bioresorbable Vascular Stents (BVS)’. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH: PART B - APPLIED BIOMATERIALS, 2019, 107(3), 624-634, DOI: 10.1002/jbm.b.34155. Xu, Q., Venet, M., Wang, W., Creagh-Flynn, J., Wang, X., Li, X., Gao, Y., Zhou, D., Zeng, M, Lara-Sáez, I., A, S.*, Tai, H., Wang, W.* ‘Versatile Hyperbranched Poly(β-hydrazide ester) Macromers as Injectable Antioxidative Hydrogels’. 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