BPharm (Hons), 1st Class, King’s College London, 1994 PhD (Pharmacology), King’s College London, 1999

Non-anticoagulant effects of glycosaminoglycans Physiological role of endogenous heparin Role of acetylcholine and its receptors in endothelial cell biology Novel inhibitors of VEGF

PEGylation and its impact on the design of new protein-based medicines. Journal article ; 2014 ; Future Med Chem ; England links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Ginn C,Khalili H,Lever R,Brocchini S Overcoming the skin barrier: Enhancement of topical delivery of hexamidine diisethionate Conference ; 2014 ; JOURNAL OF INVESTIGATIVE DERMATOLOGY links: IRIS ; UCL Discovery ; author's authors [click to collapse] : Parisi N,Matts PJ,Lever R,Hadgraft J,Lane ME Heparanase induces inflammatory cell recruitment in vivo by promoting adhesion to vascular endothelium. Journal article ; 2014 ; Am J Physiol Cell Physiol ; United States links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Lever R,Rose MJ,McKenzie EA,Page CP Fab-PEG-Fab as a potential antibody mimetic. Journal article ; 2013 ; Bioconjug Chem ; United States links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Khalili H,Godwin A,Choi JW,Lever R,Khaw PT,Brocchini S exendin-4 reverses biochemical and behavioural deficits in a pre-motor rodent model of Parkinson's disease with combined noradrenergic and serotonergic lesions (Retraction of vol 46, pg 183, 2012) Journal article ; 2013 ; NEUROPEPTIDES links: IRIS ; doi ; author's authors [click to collapse] : Rampersaud N,Harkavyi A,Giordano G,Lever R,Whitton J,Whitton PS Retraction notice to exendin-4 reverses biochemical and behavioural deficits in a pre-motor rodent model of parkinson's disease with combined noradrenergic and serotonergic lesions [YNPEP 46 (2012) 183-193] Journal article ; 2013 ; Neuropeptides links: IRIS ; UCL Discovery ; doi authors [click to collapse] : Rampersaud N,Harkavyi A,Giordano G,Lever R,Whitton J,Whitton PS Exendin-4 reverses biochemical and behavioral deficits in a pre-motor rodent model of Parkinson's disease with combined noradrenergic and serotonergic lesions Journal article ; 2012 ; Neuropeptides links: IRIS ; UCL Discovery ; doi authors [click to collapse] : Rampersaud N,Harkavyi A,Giordano G,Lever R,Whitton J,Whitton PS Comparative binding of disulfide-bridged PEG-Fabs Journal article ; 2012 ; Bioconjug Chem links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Brocchini S,Khalili H,Godwin A,Choi JW,Lever R The CRF-like peptide urocortin produces a long-lasting recovery in rats made hemiparkinsonian by 6-hydroxydopamine or lipopolysaccharide Journal article ; 2008 ; Journal of the Neurological Sciences links: IRIS ; UCL Discovery ; publisher authors [click to collapse] : Abuirmeileh A,Harkavyi A,Kingsbury AE,Lever R,Whitton PS Exendin-4 reverts behavioural and neurochemical dysfunction in a pre-motor rodent model of Parkinson's disease with noradrenergic deficit. Journal article ; 2012 ; Br J Pharmacol ; England links: IRIS ; UCL Discovery ; doi ; author's authors [click to collapse] : Rampersaud N,Harkavyi A,Giordano G,Lever R,Whitton J,Whitton P Activation of corticotropin-releasing factor receptor-2 causes bronchorelaxation and inhibits pulmonary inflammation in mice Journal article ; 2006 ; FASEB Journal links: IRIS ; UCL Discovery ; doi authors [click to collapse] : Moffatt JD,Lever R,Page CP The effects of heparin and related molecules upon the adhesion of human polymorphonuclear leucocytes to vascular endotheliumin vitro Journal article ; 2000 ; British Journal of Pharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Lever R,Hoult JRS,Page CP HIT dynamics are Fab Journal article ; 2000 ; Trends in Pharmacological Sciences links: IRIS ; UCL Discovery ; doi ; publisher authors : Lever R The effects of heparin on the adhesion of human peripheral blood mononuclear cells to human stimulated umbilical vein endothelial cells Journal article ; 2001 ; British Journal of Pharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Smailbegovic A,Lever R,Page CP Role of glycosaminoglycans in inflammation Journal article ; 2001 ; InflammoPharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Lever R,Smailbegovic A,Page CP Glycosaminoglycans, Airways Inflammation and Bronchial Hyperresponsiveness Journal article ; 2001 ; Pulmonary Pharmacology & Therapeutics links: IRIS ; UCL Discovery ; doi ; publisher authors : Lever R,Page CP Novel drug development opportunities for Heparin Journal article ; 2002 ; Nature Reviews. Drug discovery links: IRIS ; UCL Discovery ; doi ; publisher authors : Lever R,Page CP Platelets are essential for leukocyte recruitment in allergic inflammation Journal article ; 2003 ; Journal of Allergy and Clinical Immunology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Pitchford S,Yano H,Lever R,Riffovasquez Y,Ciferri S,Rose M,Gianni S,Momi S,Spina D,OConnor B Effects of heparin and related molecules upon neutrophil aggregation and elastase releasein vitro Journal article ; 2003 ; British Journal of Pharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Brown RA,Lever R,Jones NA,Page CP Interference with heparin binding and oligomerization creates a novel anti-inflammatory strategy targeting the chemokine system. Journal article ; 2004 ; Journal of Immunology links: IRIS ; UCL Discovery authors [click to collapse] : Johnson Z,Kosco-Vilbois MH,Herren S,Cirillo R,Muzio V,Zaratin P,Carbonatto M,Mack M,Smailbegovic A,Rose M,Lever R,Page CP,Wells TNC,Proudfoot AEI Effects of inhaled thrombin receptor agonists in mice Journal article ; 2004 ; British Journal of Pharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Moffatt JD,Lever R,Page CP Anti-adhesive glycoproteins in echinoderm mucus secretions Journal article ; 2004 ; Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Bavington CD,Lever R,Mulloy B,Grundy MM,Page CP,Richardson NV,McKenzie JD Activation of corticotropin-releasing factor receptor-2 causes bronchorelaxation and inhibits pulmonary inflammation in mice Journal article ; 2006 ; FASEB Journal links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Moffatt JD,Lever R,Page CP Size-fractionated heparins have differential effects on human neutrophil functionin vitro Journal article ; 2007 ; British Journal of Pharmacology links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Lever R,Lo WT,Faraidoun M,Amin V,Brown RA,Gallagher J,Page CP Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses Journal article ; 2007 ; Clinical & Experimental Allergy links: IRIS ; UCL Discovery ; doi ; publisher authors [click to collapse] : Lever R,Hefni A,Moffatt JD,Paul W,Page CP