Ph.D., Mass. Institute of Technology (1988) A.B., College of the Holy Cross (1983)

Design, synthesis and evaluation of molecules that mimic protein structure.

Curran, T. P., McTeague, T. A., Nguyen, V. D., Yennie, C. J., Handali, P. R., Sanderson-Brown, J. P., Dworsky, Z. D. "Synthesis and Conformational Behavior of Metallacyclicdipeptides Derived from Coordination of Side Chain Alkynylamino Acids to Tungsten." J. Organometallic Chem., 806, 12 (2016). Curran, T. P., Mostovoy, A. J., Curran, M. E., Berger, C. "Introducing Aliphatic Substitution with a Discovery Experiment Using Competing Nucleophiles." J. Chem. Educ., 93, 757 (2016). Curran, T. P., Boynton, A. N., Berk, S. M., Pedro, E-M. C. "Alkynyl Beta-sheet Peptidomimetics Retain Their Anti-Parallel Sheet Conformation When Coordinated to Tungsten." J. Organometallic Chem., 782, 31 (2015). Curran, T. P., Smith, W. E., Hendrickson, P. E. "Conformational Behavior of Symmetrical and Unsymmetrical Mono(Alkynylpeptide)-Tungsten Complexes." J. Organometallic Chem., 711, 15 (2012). Curran, T. P., E. L. Handy, "A 310-Helix Single Turn Enforced by Crosslinking of Lysines with 1, 1'-Ferrocenedicarboxylic Acid, J. Organometallic Chem., 694, 902 (2009). Curran, T. P., A. B. Lesser, and R. S. H. Yoon. "Turn Conformations in a Metallacyclictripeptide and a Metallacyclictetrapeptide Induced by Tungsten-Alkyne Coordination." J. Organometallic Chem., 692, 1243 (2007). Curran,T. P., K. A. Marques, and M. V. Silva. "Bis(Amino Acid) Derivatives of 1,4-Diamino-2-butyne that Adopt a C2-Symmetric Turn Conformation." Org. Biomol. Chem. 3, 4134 (2005). Curran, T. P., K. A. Marques, and S. I. Bilimoria. "A Simple, High Yield Route to cis-4-(N-Alkylamino)-L-Prolines." Lett. Org. Chem. 2, 15 (2005). Curran, T. P., R. S. H. Yoon, and B. R. Volk. "N-Terminus to C-Terminus Metallacyclicpeptides Employing Tungsten-Alkyne Coordination." J. Organometallic Chem. 689, 4837 (2004). Curran, T. P., A. L. Grant, R. L. Lucht, J. C. Carter, and J. Affonso. p-Ligands for Generating Transition Metal-Peptide Complexes: Coordination of Amino Acid Derivatives to Tungsten Utilizing Alkyne Ligands." Org. Lett. 4, 2917 (2002). Curran, T.P., Lisa A. Marcaurelle, and K.M. O'Sullivan. "A Short Synthesis of Bicyclic Dipeptides Corresponding to Xxx-L-Pro and Xxx-D-Pro Having Constrained Trans-Proline Amides." Org. Lett.1, 1225 (1999).