Gevorgyan, Vladimir
Professor
所属大学: The University of Texas at Dallas
所属学院: Department of Chemistry and Biochemistry
个人简介
2021 – Honorary Professor of Kuban State University 2018 – Markovnikov Medal, Moscow State University 2016 – Foreign Member of Latvian Academy of Sciences 2015 – Lilly Lectureship at Imperial College London, London 2014 – Visiting Professor, Sorbonne Universities, Paris 2012 – University Scholar (University of Illinois) 2012-2019–Distinguished Professor of Liberal Arts and Sciences, University of Illinois at Chicago 2012 – Honorary Professor of St. Petersburg State University 2008 – UIC Researcher of the Year 2003-2012 – Professor, University of Illinois at Chicago 1999-2003 – Associate Professor, University of Illinois at Chicago 1997-1999 – Associate Professor, Tohoku University 1996 – Assistant Professor, Tohoku University 1995 – Visiting Professor, CNR, Bologna 1993-1994 – Ciba-Geigy International Postdoctoral Fellow, Tohoku University 1992-1993 – JSPS Postdoctoral Fellow, Tohoku University 1986-1991 – Group Leader, Latvian Institute of Organic Synthesis 1984 – PhD, Latvian Institute of Organic Synthesis 1978 – BSc, Kuban State University
研究领域
Our research interests are focused on discovery and development of fundamentally interesting catalytic methodologies for broad synthetic applications. We place a special emphasis on mechanistic investigation to gain insight into the origins of chemo- and stereoselectivity of processes. Deep understanding of reaction mechanisms governs our work towards identifying the most efficient protocols and allows for expanding the scope of these methodologies. These new methods and strategies are being applied to access valuable building blocks for synthetic organic chemistry and molecules of biological importance.
近期论文
Asymmetric intermolecular allylic C–H amination of alkenes with aliphatic amines Cheung, K.P.S.; Fang J.; Mukherjee K.; Mihranyan A.; Gevorgyan, V. Science 2022, 378, 1207–1213. Palladium Hydride-Enabled Hydroalkenylation of Strained Molecules Zhang, Z.; Gevorgyan, V. J. Am. Chem. Soc. 2022, 144, 20875–20883. Targeting lipid-protein interaction to treat Syk-mediated acute myeloid leukemia Singaram, I.; Sharma, A.; Pant, S.; Lihan, M.; Park, Mi-J.; Pergande, M.; Buwaneka, P.; Hu, Y.; Mahmud, N.; Kim, You-M.; Cologna, S.; Gevorgyan, V.; Khan, I.; Tajkhorshid, E.; Cho, W. Nat. Chem. Biol. 2022, In Press. General and selective metal-free radical α-C–H borylation of aliphatic amines Sarkar, S.; Sidhant, W.; Jia, X.; Gevorgyan, V. Chem 2022, 8, 3096-3108. (Highlighted in Chem by Shu and Zhang) Recent advances in visible light-induced C(sp3)–N bond formation Rivas, M.; Palchykov V.; Jia, X.; Gevorgyan, V. Nat. Rev. Chem. 2022, 6, 544–561. Accessing Illusive E Isomers of α-Ester Hydrazones via Visible-Light-Induced Pd-Catalyzed Heck-Type Alkylation Kvasovs, N.; Gevorgyan, V. Org. Lett. 2022, 23, 4176–4181. Visible-Light-Induced Brønsted Acid Assisted Pd-Catalyzed Alkyl Heck Reaction of Diazo Compounds and N-Tosylhydrazones Zhang, Z.; Kvasovs, N.; Dubrovina, A.; Gevorgyan, V. Angew. Chem., Int. Ed. 2022, 61, e202110924. Visible Light-Induced Transition Metal Catalysis Cheung, K.P.S.; Sarkar, S.; Gevorgyan, V. Chem. Rev. 2022, 122, 1543–1625. Three-Component Visible-Light-Induced Palladium-Catalyzed 1,2-Alkyl Carbamoylation/Cyanation of Alkenes Jia, X.; Zhang, Z.; Gevorgyan, V. ACS Catal. 2021, 11, 13217–13222. Visible Light-Induced Pd-Catalyzed Alkyl-Heck Reaction of Oximes Kvasovs, N.; Iziumchenko, V.; Palchykov, V.; Gevorgyan, V. ACS Catal. 2021, 11, 3749–3754. Contemporary Methods for Generation of Aryl Radicals Kvasovs, N.; Gevorgyan, V. Chem. Soc. Rev. 2021, 50, 2244–2259. (Tutorial Review) C–H Functionalization Reactions Enabled by Hydrogen Atom Transfer to Carbon-Centered Radicals Sarkar, S.; Cheung, K.P.S.; Gevorgyan, V. Chem. Sci. 2020, 11, 12974–12993. (Perspective) Co-Catalyzed Transannulation of Pyridotriazoles with Isothiocyanates and Xanthate Esters Zhang, Z.; Gevorgyan, V. Org. Lett. 2020, 22, 8500–8504. Denitrogenative Transformations of Pyridotriazoles and Related Compounds: Synthesis of N-Containing Heterocyclic Compounds and Beyond Yadagiri, D.; Rivas, M.; Gevorgyan, V. J. Org. Chem. 2020, 85, 11030–11046. (Perspective) Photoinduced Palladium-Catalyzed Carbofunctionalization of Conjugated Dienes Proceeding via Radical-Polar Crossover Scenario: 1,2-Aminoalkylation and Beyond Cheung, K.P.S.; Kurandina, D.; Yata, T.; Gevorgyan, V. J. Am. Chem. Soc. 2020, 142, 9932–9937. Visible Light‐Induced Palladium‐Catalyzed Generation of Aryl Radicals from Aryl Triflates Ratushnyy, M.; Kvasovs, N.; Sarkar, S.; Gevorgyan, V. Angew. Chem. Int. Ed. 2020, 59, 10316–10320. Light-Induced Metal-Free Transformations of Unactivated Pyridotriazoles Zhang, Z.; Yadagiri, D.; Gevorgyan, V. Chem. Sci. 2019, 10, 8399–8404. Transition Metal- and Light-free Directed Amination of Remote Unactivated C(sp3)–H Bonds of Alcohols Kurandina, D.; Yadagiri, D.; Rivas, M.; Kavun, A.; Chuentragool, P.; Hayama, K.; Gevorgyan, V. J. Am. Chem. Soc. 2019, 141, 8104–8109. Transition-Metal-Catalyzed Alkyl Heck-Type Reactions Kurandina, D.; Chuentragool, P.; Gevorgyan, V. Synthesis 2019, 51, 985–1005. (Published as part of the 50 Years SYNTHESIS – Golden Anniversary Issue) Catalysis by Visible Light Photoexcited Palladium Complexes Chuentragool, P.; Kurandina, D.; Gevorgyan, V. Angew. Chem. Int. Ed. 2019, 58, 11586–11598.(Minireview)