Tsibouklis, John 照片

Tsibouklis, John

Reader in Polymer Science

所属大学: The University of Portsmouth

所属学院: School of Pharmacy and Biomedical Sciences

邮箱:
john.tsibouklis@port.ac.uk

个人主页:
http://www.port.ac.uk/school-of-pharmacy-and-biomedical-sciences/staff/dr-john-tsibouklis.html

个人简介

Controlled and targeted drug delivery: design and development of specific retentive delivery systems aimed at mucosal surfaces; nanomaterials for the transport of chemotherapeutant; stimuli-responsive polymer conjugates for the release of therapeutic agents. Low-surface-energy materials: synthesis, surface characterisation of polymeric materials with ultra-low-surface-energy characteristics. Bioadhesion/mucoadhesion: bioadhesive materials for therapeutic use in the eye, mouth, stomach and colon. Biomolecular recognition: receptor molecules with potential applications as either binding agents or controlled release systems; support matrices for in vitro toxicology. Bioadhesion control: development of materials that inhibit bacterial binding to biological surfaces and biomaterials; use of responsive ('smart') polymers displaying hydrophilic-hydrophobic transitions. Therapeutic agents for targeting cancer tumours: boronated cages for cancer therapy; delivery vehicles for the transport of chemotherapeutants across the blood-brain barrier. Surface science research: the use of contact angle goniometry, atomic force microscopy, X-ray photoelectron spectroscopy, infrared spectroscopy and other techniques as means of quantifying surface heterogeneity.

研究领域

Biomaterials with inherent resistance to bacterial colonisation, Bioadhesion/mucoadhesion, Surface Science Research, Colonic drug delivery, Ocular drug delivery, Boron neutron-capture therapy.