We are interdisciplinary and highly collaborative. Our projects all focus on understanding the role of small molecules in biology. We are interested in chemical communication, metabolomics, and systems biology. The primary organism that we study and use for technique development is the small free-living nematode, Caenorhabditis elegans.

Reed, L. K., Baer, C. F., and Edison, A. S.* (2017) Considerations when choosing a genetic model organism for metabolomics studies, Current Opinion in Chemical Biology 36, 7-14. Markley, J. L., Brüschweiler, R., Edison, A. S., Eghbalnia, H. R., Powers, R., Raftery, D., and Wishart, D. S. (2017) The future of NMR-based metabolomics, Current Opinion in Biotechnology 43, 34-40. Edison, A. S., Hall, R. D., Junot, C., Karp, P. D., Kurland, I. J., Mistrik, R., Reed, L. K., Saito, K., Salek, R. M., Steinbeck, C., Sumner, L. W., and Viant, M. R. (2016) The Time Is Right to Focus on Model Organism Metabolomes, Metabolites 6, 8. Hooker, J. W., Ramaswamy, V., Arora, R. K., Edison, A. S., and Brey, W. W. (2016) Effects of Dielectric Substrates and Ground Planes on Resonance Frequency of Archimedean Spirals, IEEE Transactions on Applied Superconductivity 26. Williams, C. M., Szejner-Sigal, A., Morgan, T. J., Edison, A. S., Allison, D. B., and Hahn, D. A. (2016) Adaptation to Low Temperature Exposure Increases Metabolic Rates Independently of Growth Rates, Integr Comp Biol 56, 62-72. Sud, M., Fahy, E., Cotter, D., Azam, K., Vadivelu, I., Burant, C., Edison, A., Fiehn, O., Higashi, R., Nair, K. S., Sumner, S., and Subramaniam, S. (2016) Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools, Nucleic Acids Res 44, D463-470. Ramaswamy, V., Hooker, J. W., Withers, R. S., Nast, R. E., Edison, A. S., and Brey, W. W. (2016) Development of a H-1-C-13 Dual-Optimized NMR Probe Based on Double-Tuned High Temperature Superconducting Resonators, Ieee Transactions on Applied Superconductivity 26. Liu, H., Tayyari, F., Edison, A. S., Su, Z., and Gu, L. (2016) NMR-based metabolomics reveals urinary metabolome modifications in female Sprague-Dawley rats by cranberry procyanidins, J Nutr Biochem 34, 136-145. Clendinen, C. S., Stupp, G. S., Wang, B., Garrett, T. J., and Edison, A. S. (2016) C-13 Metabolomics: NMR and IROA for Unknown Identification, Current Metabolomics 4, 116-120. Ardenkjaer-Larsen, J.H., Boebinger, G.S., Comment, A., Duckett, S., Edison, A.S., Engelke, F., Griesinger, C., Griffin, R.G., Hilty, C., Maeda, H., Parigi, G., Prisner, T., Ravera, E., Van Bentum, J., Vega, S., Webb, A., Luchinat, C., Schwalbe, H., and Frydman, L. (2015). Facing and Overcoming Sensitivity Challenges in Biomolecular NMR Spectroscopy. Angew Chem Int Ed Engl 32, 9162-85. Hooker, J. W., Ramaswamy, V., Arora, R. K., Edison, A. S., Withers, R. S., Nast, R. E., and Brey, W. W. (2015) An Empirical Expression to Predict the Resonant Frequencies of Archimedean Spirals, IEEE Trans Microw Theory 63, 2107-2114. Clendinen, C. S., Stupp, G. S., Ajredini, R., Lee-McMullen, B., Beecher, C., and Edison, A. S. (2015) An Overview of Methods using 13C for Improved Compound Identification in Metabolomics and Natural Products, Frontiers in Plant Science 6, 611. Edison, A.S., Clendinen, C.S., Ajredini, R., Beecher, C., Ponce, F.V., and Stupp, G.S. (2015). Metabolomics and Natural-Products Strategies to Study Chemical Ecology in Nematodes. Integrative and Comparative Biology 55 (3), 478-85 Wang, B., Park, E. M., King, J. B., Mattes, A. O., Nimmo, S. L., Clendinen, C., Edison, A. S., Anklin, C., and Cichewicz, R. H. (2015) Transferring Fungi to a Deuterium-Enriched Medium Results in Assorted, Conditional Changes in Secondary Metabolite Production, J Nat Prod 78 (6), 1415-21. Menger RF, Clendinen CS, Searcy LA, Edison AS, & Yost RA (2015) MALDI Mass Spectrometric Imaging of Caenorhabditis elegans. Current Metabolomics 3:130-138. Frelin, O., Huang, L., Hasnain, G., Jeffryes, J., Ziemak, M., Rocca, J., Wang, B., Rice, J., Roje, S., Yurgel, S., Gregory, J., Edison, A., Henry, C., de Crecy-Lagard, V., and Hanson, A. (2015) A directed-overflow and damage-control N-glycosidase in riboflavin biosynthesis., Biochem J 466, 137-145. Clendinen, C. S., Pasquel, C., Ajredini, R., and Edison, A. S. (2015) (13)C NMR Metabolomics: INADEQUATE Network Analysis, Anal Chem 87, 5698-5706.