B.S. (2007) Brandeis University Ph.D. (2011) Yale University Postdoc (2012-2014) Massachusetts Institute of Technology

Inorganic Chemistry

Our group strives to develop new homogeneous transition metal catalysts for use in synthetic chemistry. Catalysis is a crucial area of study, with applications in fine chemicals manufacturing, the petrochemical industry, as well as the drug discovery efforts of medicinal chemistry laboratories. The core of our research program is organometallic chemistry, an interdisciplinary area that unites the structural diversity of organic molecules with the remarkable reactivity and properties of inorganic compounds. Students have the opportunity to work in many areas, including inorganic synthesis and organic reaction methodology.

Dobereiner, G.E.; Erdogan, G.; Larsen, C.R.; Grotjahn, D.B.; Schrock, R.R. A One-Pot Tandem Olefin Isomerization/Metathesis-Coupling (ISOMET) Reaction. ACS Catalysis, 2014, 4, 3069-3076.

Dobereiner, G.E.; Yuan, J.; Schrock, R.R.; Goldman, A.S.; Hackenberg, J.D. Catalytic Synthesis of n-Alkyl Arenes through Alkyl Group Cross-Metathesis. Journal of the American Chemical Society, 2013, 135, 12572-12575.

Manas, M.G.; Graeupner, J.; Allen, L.J.; Dobereiner, G.E.; Rippy, K.C.; Hazari, N.; Crabtree, R.H. Hydrogenation of Quinaldine and Benzylic Aldehydes both Separately and Combined in a Tandem Hydrogenation朢eductive Alkylation of Quinaldine by Aldehydes with Iridium Benzoquinoline Catalysts. Organometallics, 2013, 32, 4501-4506.

Reithofer, M.R.; Dobereiner, G.E.; Schrock, R.R.; M黮ler, P. Monoaryloxide Pyrrolide (MAP) Imido Alkylidene Complexes of Molybdenum and Tungsten That Contain 2,6-Bis(2,5-R-2-pyrrolyl)phenoxide (R = i-Pr, Ph) Ligands and an Unsubstituted Metallacyclobutane on Its Way to Losing Ethylene. Organometallics, 2013, 32, 2489-2492.

Dobereiner, G.E.; Wu, J.; Manas, M.G.; Schley, N.D.; Takase, M.K.; Crabtree, R.H.; Hazari, N.; Maseras, F.; Nova, A. Mild, Reversible Reaction of Iridium(III) Amido Complexes with Carbon Dioxide. Inorganic Chemistry, 2012, 51, 9683-9693.

Yuan, J.; Schrock, R.R.; Mueller, P.; Axtell, J. C.; Dobereiner, G.E. Pentafluorophenylimido Alkylidene Complexes of Molybdenum and Tungsten. Organometallics, 2012, 31, 4650-4653.

Schley, N.D.; Dobereiner, G.E.; Crabtree, R.H. Oxidative Synthesis of Amides and Pyrroles via Dehydrogenative Alcohol Oxidation by Ruthenium Diphosphine Diamine Complexes. Organometallics, 2011, 30, 4174-4179.

Schmeier, T.J.; Dobereiner, G.E.; Crabtree, R.H.; Hazari, N. Secondary Coordination Sphere Interactions Facilitate the Insertion Step in an Iridium(III) CO2 Reduction Catalyst. Journal of the American Chemical Society, 2011, 133, 9274-9277.

Dobereiner, G.E.; Nova, A.; Schley, N.D.; Hazari, N.; Miller, S. J.; Eisenstein, O.; Crabtree, R.H. Iridium-Catalyzed Hydrogenation of N-Heterocyclic Compounds under Mild Conditions by an Outer Sphere Pathway. Journal of the American Chemical Society, 2011, 133, 7547-7562.

Nova, A.; Balcells, D.; Schley, N.D.; Dobereiner, G.E.; Crabtree, R.H.; Eisenstein, O. An Experimental-Theoretical Study of the Factors That Affect the Switch between Ruthenium-Catalyzed Dehydrogenative Amide Formation versus Amine Alkylation. Organometallics, 2010, 29, 6548-6558.

Dobereiner, G.E.; Chamberlin, C.A.; Schley, N.D.; Crabtree, R.H. Acyl Protection Strategy for Synthesis of a Protic NHC Complex via N-Acyl Methanolysis. Organometallics, 2010, 29, 5728-5731.

Dobereiner, G.E.; Crabtree, R.H. Dehydrogenation as a Substrate-Activating Strategy in Homogeneous Transition-Metal Catalysis. Chemical Reviews, 2010, 110, 681-703.

Chen, X.; Dobereiner, G.E.; Hao, X.S.; Giri, R.; Maugel, N.; Yu, J.Q. Cu(II)-Mediated Oxidative Dimerization of 2-Phenylpyridine Derivatives. Tetrahedron 2009, 65, 3085-3089.