AB, Harvard College, Biochemistry & Molecular Biology (1983) PhD, Stanford University, Medical Information Sciences (1989) MD, Stanford University, Medicine (1990)

A research roadmap for next-generation sequencing informatics SCIENCE TRANSLATIONAL MEDICINEAltman, R. B., Prabhu, S., Sidow, A., Zook, J. M., Goldfeder, R., Litwack, D., Ashley, E., Asimenos, G., Bustamante, C. D., Donigan, K., Giacomini, K. M., Johansen, E., Khuri, N., Lee, E., Liang, X. S., Salit, M., Serang, O., Tezak, Z., Wall, D. P., Mansfield, E., Kass-Hout, T.All Authors2016; 8 (335) Relating Essential Proteins to Drug Side-Effects Using Canonical Component Analysis: A Structure-Based Approach. Journal of chemical information and modelingLiu, T., Altman, R. B.2015; 55 (7): 1483-1494 Learning the Structure of Biomedical Relationships from Unstructured Text. PLoS computational biologyPercha, B., Altman, R. B.2015; 11 (7) Translational Bioinformatics: Linking the Molecular World to the Clinical World CLINICAL PHARMACOLOGY & THERAPEUTICSAltman, R. B.2012; 91 (6): 994-1000 Data-Driven Prediction of Drug Effects and Interactions SCIENCE TRANSLATIONAL MEDICINETatonetti, N. P., Ye, P. P., Daneshjou, R., Altman, R. B.2012; 4 (125) Clinical assessment incorporating a personal genome LANCETAshley, E. A., Butte, A. J., Wheeler, M. T., Chen, R., Klein, T. E., Dewey, F. E., Dudley, J. T., Ormond, K. E., Pavlovic, A., Morgan, A. A., Pushkarev, D., Neff, N. F., Hudgins, L., Gong, L., Hodges, L. M., Berlin, D. S., Thorn, C. F., Sangkuhl, K., Hebert, J. M., Woon, M., Sagreiya, H., Whaley, R., Knowles, J. W., Chou, M. F., Thakuria, J. V., Rosenbaum, A. M., Zaranek, A. W., Church, G. M., Greely, H. T., Quake, S. R., Altman, R. B.All Authors2010; 375 (9725): 1525-1535 Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data NEW ENGLAND JOURNAL OF MEDICINEKlein, T. E., Altman, R. B., Eriksson, N., Gage, B. F., Kimmel, S. E., Lee, M. M., Limdi, N. A., Page, D., Roden, D. M., Wagner, M. J., Caldwell, M. D., Johnson, J. A., Chen, Y. T., Wen, M. S., Caraco, Y., Achache, I., Blotnick, S., Muszkat, M., Shin, J. G., Kim, H. S., Suarez-Kurtz, G., Perini, J. A., Silva-Assuncao, E., Anderson, J. L., Horne, B. D., Carlquist, J. F., Caldwell, M. D., Berg, R. L., Burmester, J. K., Goh, B. C., Lee, S. C., Kamali, F., Sconce, E., Daly, A. K., Wu, A. H., Langaee, T. Y., Feng, H., Cavallari, L., Momary, K., Pirmohamed, M., Jorgensen, A., Toh, C. H., Williamson, P., McLeod, H., Evans, J. P., Weck, K. E., Brensinger, C., Nakamura, Y., Mushiroda, T., Veenstra, D., Meckley, L., Rieder, M. J., Rettie, A. E., Wadelius, M., Melhus, H., Stein, C. M., Schwartz, U., Kurnik, D., Deych, E., Lenzini, P., Eby, C., Chen, L. Y., Deloukas, P., Motsinger-Reif, A., Sagreiya, H., Srinivasan, B. S., Lantz, E., Chang, T., Ritchie, M., Lu, L. S., Shin, J. G.All Authors2009; 360 (8): 753-764 PharmGKB summary: very important pharmacogene information for MT-RNR1. Pharmacogenetics and genomicsBarbarino, J. M., McGregor, T. L., Altman, R. B., Klein, T. E.2016; 26 (12): 558-567 Imputing Gene Expression to Maximize Platform Compatibility. BioinformaticsZhou, W., Han, L., Altman, R. B.2016 Estimation of Maximum Recommended Therapeutic Dose Using Predicted Promiscuity and Potency. Clinical and translational scienceLiu, T., Oprea, T., Ursu, O., Hasselgren, C., Altman, R. B.2016