I am interested in the functioning of cys-loop ligand gated ion channels (CysLGICs) in insect species, including those of the mosquito. Mosquitoes are becoming increasingly resistant to insecticides, which bind to these receptors. Therefore, by understanding these receptors in more detail, we may be able to identify the mechanism for insecticide resistance. This research therefore has implications for the spread of tropical diseases, including Malaria and Lymphatic Filariasis.

Taylor-Wells, J, Brooke, B.D., Bermudez, I. and Jones, A.K. The neonicotinoid imidacloprid, and the pyrethroid deltamethrin, are antagonists of the insect Rdl GABA receptor. J Neurochem In press. Taylor-Wells, J and Meredith, D (2014) The Signature Sequence Region of the Human Drug Transporter Organic Anion Transporting Polypeptide 1B1 Is Important for Protein Surface Expression. Journal of Drug Delivery. Vol. 2014. Article ID 129849. doi:10.1155/2014/129849.