Irons,  Sarah 照片

Irons, Sarah

Research Fellow

所属大学: Oxford Brookes University

所属学院: Department of Biological and Medical Sciences

邮箱:
sarahirons@brookes.ac.uk

个人主页:
http://bms.brookes.ac.uk/staff/sarah-irons

个人简介

I gained my PhD in plant cell biology from Oxford Brookes University in 2004, which was provided great training in different imaging techniques which I continue to use today. I have since worked in a number of groups within the university, firstly continuing in the Plant Endomembrane Research Group working on pharmaceutical protein production in plants. Then moving to the Genomic Instability Research Group in 2008, looking at non-targeted effects in cells exposed to low levels of radiation. From here I moved to the Insect Virus Research Group where I study virus-host cell interactions.

研究领域

My research focus is on studying the interactions between baculovirus and the insect cell. I am interested in how baculovirus travels within cells and in particular, the role of the cytoskeleton in transport of virus from the nucleus to cell surface. As well as in detailed analysis of virus exit from the nucleus. I am using fluorescent protein tagged virus proteins and a range of markers that label different cellular compartments to look at what happens during virus infection in live cells. I also use electron microscopy to uncover how the host cell changes during viral infection in high resolution.