Cell and Molecular Biology

Spreading of a Prion Domain from Cell-to-Cell by Vesicular Transport in Caenorhabditis elegans. Nussbaum-Krammer CI, Park K-W, Li L, Melki R, and Morimoto RI. PLoS Genetics. 2013 March 28;9(3):e1003351. Regulation of Organismal Proteostasis by Transcellular Chaperone Signaling. van Oosten-Hawle P, Porter RS, and Morimoto RI. Cell. 2013 June 6;153(6):1366-1378. The nascent polypeptide-associated complex is a key regulator of proteostasis. Kirstein-Miles J, Scior A, Deuerling E, and Morimoto RI. EMBO Journal. 2013 May 15;32(10):1451-1468. Neuronal reprograming of protein homeostasis by calcium-dependent regulation of the heat shock response. Silva MC, Amaral MD, Morimoto RI. PLoS Genet. 2013 Aug;9(8):e1003711. Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins. Ciryam P, Tartaglia GG, Morimoto RI, Dobson CM, Vendruscolo M. Cell Rep. 2013 Nov 14;5(3):781-90.