B.S. Nanjing University, Nanjing, China M.S. Nanjing University, Nanjing, China Ph.D. The University of Iowa, 2004 Postdoctoral Associate, Iowa State University and Ames Laboratory, U.S. Department of Energy, 2006-2011

Analytical Chemistry

We are interested in developing and applying optical imaging and spectroscopic techniques to solve chemical, biological, material, and bioanalytical problems.

Detection of the potential pancreatic cancer marker MUC4 in serum using Surface-Enhanced Raman Scattering. Gufeng Wang, Robert J. Lipert, Maneesh Jain, Sukhwinder Kaur, Subhankar Chakraboty, Maria P. Torres, Surinder K. Batra, Randall E. Brand, and Marc D. Porter. Anal. Chem. (Accepted) Whole cell scan using automatic variable-angle and variable-illumination-depth pseudo total internal reflection fluorescence microscopy. Wei Sun, Aoshuang Xu, Kyle Marchuk, Gufeng Wang, and Ning Fang. J. Assoc. Lab. Automat. (Accepted) Single particle orientation and rotation tracking discloses distinctive rotational dynamics of drug delivery vectors on live cell membranes. Yan Gu, Wei Sun, Gufeng Wang, and Ning Fang. J. Am. Chem. Soc. Resolving rotational motions of nano-objects in engineered environments and live cells with gold nanorods and Differential Interference Contrast Microscopy. Gufeng Wang§, Wei Sun§, Yong Luo, and Ning Fang. J. Am. Chem. Soc. 2010, 132, 16417-16422. Influence of gold nanorod geometry on the optical response under Differential Interference Contrast Microscopy. Anthony S. Stender, Gufeng Wang, Wei Sun, and Ning Fang. ACS Nano 2010, 4, 7667-7675. Rotationally-induced hydrodynamics: Fundamentals and applications to high speed bioassays. Gufeng Wang, Jeremy D. Driskell, April A. Hill, Eric J. Dufek, Michael C. Granger, Robert J. Lipert, and Marc D. Porter. Annu. Rev. Anal. Chem. 2010, 3, 387-407. Optical imaging of non-fluorescent nanoparticle probes in living cells. Gufeng Wang, Anthony Stender, Wei Sun, and Ning Fang. Analyst, 2010, 135, 215-221. (Cover story) Auto-calibrated scanning-angle prism-type total internal reflection fluorescence microscopy for nanometer-precision axial position determination. Wei Sun, Kyle Marchuk, Gufeng Wang, and Ning Fang. Anal. Chem. 2010, 82, 2441–2447. Wavelength-dependent differential interference contrast microscopy: Multiplexing detection using non-fluorescent nanoparticles. Yong Luo, Wei Sun, Yan Gu, Gufeng Wang, and Ning Fang. Anal. Chem. 2010, 82, 6675-6679. Control of antigen mass transport via capture substrate rotation: Binding kinetics and implications on immunoassay speed and detection limit. Gufeng Wang, Jeremy D. Driskell, Robert J. Lipert, and Marc D. Porter. Anal. Chem. 2009, 81, 6175-6185. Mixed monolayers on gold nanoparticle labels for multiplexed surface-enhanced Raman scattering-based immunoassays. Gufeng Wang, Hye-Young Park, and Robert J. Lipert. Anal. Chem. 2009, 81, 9643-9650.

Wei Sun§, Gufeng Wang§, Ning Fang and Edward S. Yeung. Wavelength-dependent differential interference contrast microscopy: Selectively imaging nanoparticle probes in live cells. Anal. Chem. 2009, 81, 9203–9208 (§Equal contribution). (Cover Story).