B.S. with Distinction and Honors in Chemistry, 1978 Indiana University Ph.D., 1983, The Rockefeller University Post-doctoral Fellow, 1983-1984, The Rockefeller University

Organic/Bio-organic/and Materials Chemistry

Our research makes use of synthetic, mechanistic, and analytical chemistry to understand basic scientific principles underlying photochemical phenomena in organized molecular architectures. Because photosynthesis is paradigmatic our chief focus concerns the fundamental chemistry of tetrapyrrole macrocycles.

"Extending the Short and Long Wavelength Limits of Bacteriochlorin Near-Infrared Absorption via Dioxo- and Bisimide-Functionalization," Vairaprakash, P.; Yang, E.; Sahin, T.; Taniguchi, M.; Krayer, M.; Diers, J. R.; Wang, A.; Niedzwiedzki, D. M.; Lindsey, J. S.; Bocian, D. F.; Holten, D. J. Phys. Chem. B 2015, in press. "Photophysical Properties and Electronic Structure of Chlorin–Imides: Bridging the Gap Between Chlorins and Bacteriochlorins," Faries, K. A.; Diers, J. R.; Springer, J. W.; Yang, E.; Ptaszek, M.; Lahaye, D.; Krayer, M.; Taniguchi, M.; Kirmaier, C.; Lindsey, J. S.; Bocian, D. F.; Holten, D. J. Phys. Chem. B 2015, in press. "Hydrophilic Bioconjugatable trans-AB-Porphyrins and Peptide Conjugates," Sahin, T.; Vairaprakash, P.; Borbas, K. E.; Balasubramanian, T.; Lindsey, J. S. J. Porphyrins Phthalocyanines 2015, 19, in press. "Progress Towards Synthetic Chlorins with Graded Polarity, Conjugatable Substituents, and Wavelength Tunability," Ra, D.; Gauger, K. A.; Muthukumaran, K.; Balasubramanian, T.; Chandrashaker, V.; Taniguchi, M.; Yu, Z.; Talley, D. C.; Ehudin, M.; Ptaszek, M.; Lindsey, J. S. J. Porphyrins Phthalocyanines 2015, 19, in press. (Cover art for the issue containing paper 327) "Effects of Substituents on Synthetic Analogs of Chlorophylls. Part 4: How Formyl Group Location Dictates the Spectral Properties of Chlorophylls b, d and f," Yuen, J.; Harris, M. A.; Liu, M.; Diers, J. R.; Kirmaier, C.; Bocian, D. F.; Lindsey, J. S.; Holten, D. Photochem. Photobiol. 2015, 91, 331–342. "Panchromatic Absorbers for Solar Light-Harvesting," Alexy, E. J.; Yuen, J. M.; Chandrashaker, V.; Diers, J. R.; Kirmaier, C.; Bocian, D. F.; Holten, D.; Lindsey, J. S. Chem. Commun. 2014, 50, 14512–14515. "Polarity-Tunable and Wavelength-Tunable Bacteriochlorins Bearing a Single Carboxylic Acid or NHS Ester. Use in a Protein Bioconjugation Model System," Jiang, J.; Chen, C.-Y.; Zhang, N.; Vairaprakash, P.; Lindsey, J. S. New J. Chem. 2015, 39, 403–419. "Enhanced Light-harvesting Capacity by Micellar Assembly of Free Accessory Chromophores and LH1-like Antennas," Harris, M. A.; Sahin, T.; Jiang, J.; Vairaprakash, P.; Parkes-Loach, P. S.; Niedzwiedzki, D. M.; Kirmaier, C.; Loach, P. A.; Bocian, D. F.; Holten, D.; Lindsey, J. S. Photochem. Photobiol. 2014, 90, 1264–1276. "Vibronic Characteristics and Spin-Density Distributions in Bacteriochlorins as Revealed by Spectroscopic Studies of 16 Isotopologues. Implications for Energy- and Electron-Transfer in Natural Photosynthesis and Artificial Solar-Energy Conversion," Diers, J. R.; Tang, Q.; Hondros, C. J.; Chen, C.-Y.; Holten, D.; Lindsey, J. S.; Bocian, D. F. J. Phys. Chem. B 2014, 118, 7520–7532. "Stable Synthetic Mono-Substituted Cationic Bacteriochlorins Mediate Selective Broad-Spectrum Photoinactivation of Drug-Resistant Pathogens at Nanomolar Concentrations," Huang, L.; Krayer, M.; Roubil, J. G. S.; Huang, Y.-Y.; Holten, D.; Lindsey, J. S.; Hamblin, M. R. J. Photochem. Photobiol. B: Biol. 2014, 141, 119–127. "NMR Spectral Properties of 16 Synthetic Bacteriochlorins with Site-Specific 13C or 15N Substitution," Chen, C.-Y.; Taniguchi, M.; Lindsey, J. S. J. Porphyrins Phthalocyanines 2014, 18, 433–456. (Cover art for the issue containing paper 320) "Amphiphilic, Hydrophilic, or Hydrophobic Synthetic Bacteriochlorins in Biohybrid Light-Harvesting Architectures. Consideration of Molecular Designs," Jiang, J.; Reddy, K. R.; Pavan, M. P.; Lubian, E.; Harris, M. A.; Jiao, J.; Kirmaier, C.; Parkes-Loach, P. S.; Loach, P. A.; Bocian, D. F.; Holten, D.; Lindsey, J. S. Photosyn. Res. 2014, 122, 187–202. "Photophysical Properties and Electronic Structure of Retinylidene–Chlorin–Chalcones," Springer, J. W.; Taniguchi, M.; Krayer, M.; Ruzié, C.; Diers, J. R.; Niedzwiedzki, D. M.; Bocian, D. F.; Lindsey, J. S.; Holten, D. Photochem. Photobiol. Sci. 2014, 13, 634–650. "Regioselective b-Pyrrolic Bromination of Hydrodipyrrin–Dialkylboron Complexes Facilitates Access to Synthetic Models for Chlorophyll f," Liu, M.; Ptaszek, M.; Mass, O.; Minkler, D. J.; Sommer, R. D.; Bhaumik, J.; Lindsey, J. S. New J. Chem. 2014, 38, 1717–1730. "Versatile Design of Biohybrid Light-Harvesting Architectures to Tune Location, Density and Spectral Coverage of Attached Synthetic Chromophores for Enhanced Energy Capture," Harris, M. A.; Jiang, J.; Niedzwiedzki, D. M.; Jiao, J.; Taniguchi, M.; Kirmaier, C.; Loach, P. A.; Bocian, D. F.; Lindsey, J. S.; Holten, D.; Parkes-Loach, P. S. Photosyn. Res. 2014, 121, 35-48. "Probing Electronic Communication for Efficient Light-Harvesting Functionality: Dyads Containing a Common Perylene and a Porphyrin, Chlorin, or Bacteriochlorin," Yang, E.; Wang, J.; Diers, J. R.; Niedzwiedzki, D. M.; Kirmaier, C.; Bocian, D. F.; Lindsey, J. S.; Holten, D. J. Phys. Chem. B 2014, 118, 1630–1647. "Statistical Considerations on the Formation of Circular Photosynthetic Light-Harvesting Complexes from Rhodopseudomonas palustris," Taniguchi, M.; Henry, S.; Cogdell, R. J.; Lindsey, J. S. Photosyn. Res. 2014, 121, 49-60. "Synthesis of 24 Bacteriochlorin Isotopologues, Each Containing a Symmetrical Pair of 13C or 15N Atoms in the Inner Core of the Macrocycle," Chen, C.-Y.; Bocian, D. F.; Lindsey, J. S. J. Org. Chem. 2014, 79,1001–1016. "Hydrophilic Tetracarboxy Bacteriochlorins for Photonics Applications," Jiang, J.; Vairaprakash, P.; Reddy, K. R.; Sahin, T.; Pavan, M. P.; Lubian, E.; Lindsey, J. S. Org. Biol. Chem. 2014, 12, 86–103. "Synthesis and Photophysical Properties of Chlorins Bearing 0–4 Distinct Meso-Substituents," Aravindu, K.; Kim, H.-J.; Taniguchi, M.; Dilbeck, P. L.; Diers, J. R.; Bocian, D. F.; Holten, D.; Lindsey, J. S. Photochem. Photobiol. Sci. 2013, 12, 2089–2109.

"Integration of Multiple Chromophores with Native Photosynthetic Antennas to Enhance Solar Energy Capture and Delivery," Harris, M. A.; Parkes-Loach, P. S.; Springer, J. W.; Jiang, J.; Martin, E. C.; Qian, P.; Jiao, J.; Niedzwiedzki, D. M.; Kirmaier, C.; Olsen, J. D.; Bocian, D. F.; Holten, D.; Hunter, C. N.; Lindsey, J. S.; Loach, P. A. Chem. Sci. 2013, 4, 3924–3933.