Dr Murthi's projects are focused on translational outcomes in obstetrics research. Her major research interests lie primarily in understanding the molecular mechanisms of placental insufficiency leading to human fetal growth restriction. She has generated more than 80 publications in this field. Her laboratory also studies the molecular targets of placental pathogenesis in preeclampsia and gestational diabetes during pregnancy.

An EG-VEGF-dependent decrease in homeobox gene NKX3.1 contributes to cytotrophoblast dysfunction: a possible mechanism in human fetal growth restriction Murthi, P., Brouillet, S., Pratt, A., Borg, A. J., Kalionis, B., Goffin, F., Tsatsaris, V., Munaut, C., Feige, J-J., Benharouga, M., Fournier, T. & Alfaidy, N. 2015 In : Molecular Medicine. 21, 1, p. 645 - 656 12 p. Anti-angiogenic collagen fragment arresten is increased from 16 weeks' gestation in pre-eclamptic plasma Yong, H. E. J., Murthi, P., Wong, M. H., Kalionis, B., Brennecke, S. P. & Keogh, R. J. 2015 In : Placenta. 36, 11, p. 1300 - 1309 10 p. Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction Borg, A. J., Yong, H. E. J., Lappas, M., Degrelle, S. A., Keogh, R. J., Da Silva Costa, F., Fournier, T., Abumaree, M., Keelan, J. A., Kalionis, B. & Murthi, P. 2015 In : Reproduction. 149, 5, p. 523 - 532 10 p. Effects of normal and high circulating concentrations of activin A on vascular endothelial cell functions and vasoactive factor production Yong, H. E. J., Murthi, P., Wong, M. H., Kalionis, B., Cartwright, J. E., Brennecke, S. P. & Keogh, R. J. 2015 In : Pregnancy Hypertension: an international journal of women's cardiovascular health. 5, 4, p. 346 - 353 8 p. Genome-wide transcriptome directed pathway analysis of maternal pre-eclampsia susceptibility genes Yong, H. E. J., Melton, P. E., Johnson, M. P., Freed, K. A., Kalionis, B., Murthi, P., Brennecke, S. P., Keogh, R. J. & Moses, E. K. 2015 In : PLoS ONE. 10, 5 (e0128230), p. 1 - 15 15 p.