Autexier, Chantal 照片

Autexier, Chantal

Professor

所属大学: McGill University

所属学院: Department of Anatomy and Cell Biology

邮箱:
chantal.autexier@mcgill.ca

个人主页:
http://www.ladydavis.ca/en/chantalautexier

研究领域

Mechanism and regulation of telomerase and telomere function in mammals.

近期论文

Chu, T.W., D’Souza, Y. and Autexier, C. 2015. The insertion in fingers domain in human telomerase can mediate enzyme processivity and telomerase recruitment to telomeres in a TPP1-dependent manner. Molecular and Cellular Biology. 2015 Oct 26. pii: MCB.00746-15. [Epub ahead of print] D’Souza, Y., Lauzon, C., Chu, T.W., and Autexier, C. 2013. Regulation of human telomere length and homeostasis by telomerase enzyme processivity. J. Cell Science. 126, 676-87. Nov 23. [Epub ahead of print]. D’Souza, Y., Chu, T.W., Autexier, C. 2013. A translocation-defective telomerase with low levels of activity and processivity stabilizes short telomeres and confers immortalization. Mol. Biol. Cell. 24, 1469-79. Epub 2013 Feb 27. Brault, M.E., Lauzon, C. and Autexier, C. 2013. Dyskeratosis congenita mutations in dyskerin SUMOylation consensus sites lead to impaired telomerase RNA accumulation and telomere defects. Hum. Mol. Genet. 22, 3498-507. Epub 2013 Brault, M.E. and Autexier, C. 2011. Telomeric recombination is induced by dysfunctional telomeres. Mol. Biol. Cell. 22, 179-188. Epub 2010 Nov 30.