Biological/Physical

Translating HIV Sequences into Quantitative Fitness Landscapes Predicts Viral Vulnerabilities for Rational Immunogen Design, with A. Ferguson et al., Immunity, 38, 606-617 (2013).

“Coordinate linkage of HIV evolution reveals regions of immunological vulnerability”, with V Dahirel et al., Proc Natl. Acad. Sci, 108, 11530-11535 (2011).

Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection, Nature (2010)

Statistical mechanical concepts in immunology, Ann. Rev. Phys. Chem. (2010)

Seeing in numbers, Scientist (2010)

Pairing computational with experimentation: a powerful coupling for understanding T cell signaling, Nature Reviews Immunology (2010)

Digital signaling and hysteresis characterize ras activation in lymphoid cells, Cell (2009)

Efficient stochastic simulation of reaction-diffusion via direct compilation, Bioinformatics (2009)

Thymic selection of T cell receptors as an extreme value problem, Phys Rev Lett (2009)

How the thymus designs antigen-specific and self-tolerant T cell receptor sequences, PNAS (2008)

“The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse”, with S. Cemarski et al., Immunity (2007).

“CD4 Coordinates Lck Accumulation in the Immunological Synapse: Implications for the Sensitivity of T Cells to Antigen”, Nature Immunology (2004)

“The Immunological Synapse Balances T Cell Receptor Signaling and Degradation”, Science (2003)

Synaptic pattern formation during cellular recognition, PNAS (2001)