Received A.B. degree from Rutgers University in 1968 Received Ph.D. degree from the Massachusetts Institute of Technology (with G. M. Whitesides) in 1972. A Member of the faculty at Marquette University from 1972 to 1985. He joined the Department of Chemistry of Lehigh University in 1985. University Distinguished Professor in Lehigh

Supramolecular chemistry applied to problems in materials science, biology and medicine

Research Interests:

Lipids and membranes, drug delivery, drug design, Langmuir-Blodgett films

Teaching Interests:

Lipids and membranes, organic chemistry, undergraduate research en masse

Krause, M.; Daly, T.; Almeida, P. F.; Regen, S. L. Push–Pull Mechanism for Lipid Raft Formation, Langmuir, Article ASAP

Lin, C.; Chen, Q.; Yi, S.; Wang, M.; Regen, S. L. Polyelectrolyte Multilayers on PTMSP as Asymmetric Membranes for Gas Separations: Langmuir–Blodgett versus Self-Assembly Methods of Anchoring, Langmuir, 2014, 30 (3), pp 687–691

Janout, V.; Cline, L. L.; Feuston, B. P.; Klein, L.; O’Brien, A.; Tucker, T.; Yuan, Yu.; O’Neill-Davis, L. A.; Peiffer, R. L.; Nerukar, S. S.; Jadhav, V.; Tellers, D. M.; Regen, S. L. Molecular Umbrella Conjugate for the Ocular Delivery of siRNA, Bioconjugate Chem., 2014, 25 (2), pp 197–201

Wang, M.; Yi, S.; Janout, V.; Regen, S. L. A 7 nm Thick Polymeric Membrane With a H2/CO2 Selectivity of 200 That Reaches the Upper Bound, Chem. Mater., 2013, 25 (19), pp 3785–3787

Wang, M.; Janout, V.; Regen, S. L. Unexpected barrier properties of structurally matched and unmatched polyelectrolyte multilayers, Chem. Commun., 2013, 49, 3576-3578

Krause, M.; Turkyilmaz, S.; Regen, S. L. Surface Occupancy Plays a Major Role in Cholesterol’s Condensing Effect, Langmuir, 2013, 29 (33), pp 10303–10306

Wang, M.; Janout, V.; Regen, S. L. Gas Transport across Hyperthin Membranes, Acc. Chem. Res., 2013, 46 (12), pp 2743-2754

Daly, T. A.; Almeida, P. F.; Regen, S. L. Sorting of Lipidated Peptides in Fluid Bilayers: A Molecular-Level Investigation, J. Am. Chem. Soc., 2012, 134, 17245-17252.

Janout, V.; Daly, T. A.; Cline, L. L.; Kulp, L. J.; Regen, S. L. Stimulated Release of Cholesterol From Liposomal Membranes by a PEGylated Phospholipid, Bioconjugate Chem., 2012, 23,336-339.

Wang, M.; Janout, V.; Regen, S. L. Minimizing Defects in Polymer-based Langmuir-Blodgett Monolayers and Bilayers Via Gluing Langmuir, 2012, 28, 4614-4617.

Daly, T. A.; Wang, M.; Regen, S. L. The Origin of Cholesterol's Condensing Effect Langmuir,2011, 27, 2159-2161.

Cline, L. L.; Janout, V.; Fisher, M.; Juliano, R. L.; Regen, S. L. A Molecular Umbrella Approach to the Intracellular Delivery of siRNA, Bioconjugate Chem., 2011, 22, 2210-2216.

Turkyilmaz, S.; Almeida, P. F.; Regen, S. L. Effects of Isoflurane, Halothane, and Chloroform on the Interactions and Lateral Organization of Lipids in the Liqiod-Ordered Phase, Langmuir,2011, 27, 14380-14385.

Wang, M.; Janout, V.; Regen, S. L. Hyper-thin Organic Membranes with Exceptional H2/CO2Permeation Selectivity: Importance of Ionic Crosslinking and Self-Healing, Chem. Comm.,2011, 47, 2387-2389

Wang, M.; Janout, V.; Regen, S. L. Glued Langmuir-Blodgett Bilayers from Calix[n]arenes: Influence of Calix[n]arene Size on Ionic Cross-Linking, Film Thickness, and Permeation Selectivity, Langmuir, 2010, 26, 12988-12993.

Janout, V.; Turkyilmaz, S.; Wang, M.; Wang, Y.; Manaka, Y.; Regen, S. L. An Upside Down View of Cholesterol's Condensing Effect: Does Surface Occupancy Play a Role? Langmuir,2010, 26, 5316-5318.

Turkyilmaz, S.; Mitomo, H.; Chem, W.-H.; Regen, S. L. Phospholipid Complexation of General Anesthetics in Fluid Bilayers Langmuir, 2010, 26, 5309-5311.

Wang, Y.; Janout, V.; Regen, S. L. Creating Poly(ethylene oxide)-Based Polyelectrolytes for Thin Film Construction Using an Ionic LInker Strategy, Chem. Mater., 2010, 22, 1285-1287.

Chen, W.-H.; Janout, V.; Kondo, M,; Mosoian, A.; Goar, M.; Petrov, R. R.; Klotman, M. E.; Regen, S. L., A Fine Line Between Molecular Umbrella Transport and Ionophoric Activity,Bioconj. Chem., 2009, 20, 1711-1715.

Mitomo, H.; Chen, W.-H.; Regen, S. L., Oxysterol Induced Rearrangement of the Liquid-Ordered Phase: A Possible Link to Alzheimer's Disease?, J. Am. Chem. Soc., 2009, 131,12354-12357.