NUDT2 disruption elevates diadenosine tetraphosphate (Ap4A) and down-regulates immune response and cancer promotion genesMarriott, A.S., Vasieva, O., Fang, Y., Copeland, N.A., McLennan, A.G., Jones, N.J. 4/05/2016 In: PLoS ONE. 11, 5, 35 p. Diadenosine 5′, 5′′′-P1,P4-tetraphosphate (Ap4A) is synthesized in response to DNA damage and inhibits the initiation of DNA replication.Marriott, A.S., Copeland, N., Cunningham, R., Wilkinson, M.C., McLennan, A.G., Jones, N.J. 09/2015 In: DNA Repair. 33, p. 90-100. 11 p. Supramolecular assemblies underpin turnover of outer membrane proteins in bacteriaRassam, P., Copeland, N., Birkholz, O., Toth, C., Chavent, M., Cross, S., Housden, N., Kaminska, R., Seger, U., Quinn, D., Garrod, T., Sansom, M.S., Piehler, J., Baumann, C.G., Kleanthous, C. 10/06/2015 In: Nature. 18 p. Cyclin A/CDK2 mediated phosphorylation of CIZ1 blocks replisome formation and initiation of mammalian DNA replicationCopeland, N., Sercombe, H.E., Wilson, R.H.C., Coverley, D. 15/04/2015 In: Journal of Cell Science. 128, 8, p. 1518-1527. 10 p. Cancer-associated variant expression and interaction of CIZ1 with cyclin A1 in differentiating male germ cellsGreaves, E.A., Copeland, N.A., Coverley, D., Ainscough, J.F.X. 15/05/2012 In: Journal of Cell Science. 125, p. 2466-2477. 12 p. Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cellsMunkley, J., Copeland, N.A., Moignard, V., Knight, J.R.P., Greaves, E., Ramsbottom, S.A., Pownall, M.E., Southgate, J., Ainscough, J.F., Coverley, D. 2011 In: Nucleic Acids Research. 39, 7, p. 2671-2677. 7 p. Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitroCopeland, N.A., Sercombe, H.E., Ainscough, J.F.X., Coverley, D. 1/04/2010 In: Journal of Cell Science. 123, 7, p. 1108-1115. 8 p. Cancer-associated missplicing of exon 4 influences the subnuclear distribution of the DNA replication factor CIZ1.Rahman, F.A., Ainscough, J.F.X., Copeland, N., Coverley, D. 10/2007 In: Human Mutation. 28, 10, p. 993-1004. 12 p. The role of an activating peptide in protease-mediated suicide of Escherichia coli K12.Copeland, N., Kleanthous, C. 7/01/2005 In: Journal of Biological Chemistry. 280, 1, p. 112-117. 6 p. Identification of essential residues within Lit, a cell death peptidase of Escherichia coli K-12.Copeland, N., Bingham, R., Georgiou, T., Cooper, P., Kleanthous, C. 22/06/2004 In: Biochemistry. 43, 24, p. 7948-7953. 6 p