Shearman, Gemma
Dr
所属大学: Kingston University
所属学院: School of Pharmacy and Chemistry
个人主页:
http://sec.kingston.ac.uk/about-SEC/people/academic/view_profile.php?id=2255
研究领域
1. Engineering principles in membrane biophysics 2. Designer lipids and mesoscale materials for future drug delivery 3. Tools and technologies for health-related applications Aligned with the above is a side interest in the democratisation of science. Pedagogic research interests include curriculum design and revision technique.
近期论文
F.L. Lopez, G.C. Shearman, S. Gaisford, G.R. Williams, Amorphous formulations of indomethacin and griseofulvin prepared by electrospinning. Mol. Pharmaceutics, 2014, DOI: 10.1021/mp500391y. U.E. Illangakoon, H. Gill, G.C. Shearman, M. Parhizkar, S. Mahalingam, N.P. Chatterton, G.R. Williams, Fast dissolving paracetamol / caffeine nanofibers prepared by electrospinning. Int. J. Pharm, 2014, 477(1-2), 369-379. V.D. Gordon, P.A. Beales, G.C. Shearman, Z. Zhao, J.M. Seddon, W.C.K. Poon, S.U. Egelhaaf, Solid-like domains in mixed lipid bilayers: effect of membrane lamellarity and transition pathway. In Advances in Planar Lipid Bilayers and Liposomes, eds. A. Iglic, C.V. Kulkarni, ADPLAN, UK: Academic Press, 2014, 20, 137-154. G.C. Shearman, Taking 'Concepts in Chemistry' to completion: redesigning a first-year undergraduate module, Investigations in University Teaching and Learning, 2014, 9, 36-42. G.C. Shearman, N.J. Brooks, G.J.T. Tiddy, M. Sztucki, R.H. Templer, R.V. Law, O. Ces, J.M. Seddon, A lyotropic inverse ribbon phase in a branched-chain polyoxyethylene surfactant: pressure effects. Soft Matter, 2011, 7(9), 4386-4390. A.I.I. Tyler, G.C. Shearman, N.J. Brooks, H. Delacroix, R.V. Law, R.H. Templer, O. Ces, J.M. Seddon, Hydrostatic pressure effects on a hydrated lipid inverse micellar Fd3m cubic phase. Phys. Chem. Chem. Phys., 2011, 13(8), 3033-3038. G.C. Shearman, A.I.I. Tyler, N.J. Brooks, R.H. Templer, O. Ces, R.V. Law, J.M. Seddon, Ordered micellar and inverse micellar lyotropic phases. Liq. Cryst., 2010, 37(6-7), 679-694. G.C. Shearman, O. Ces, R.H. Templer, Towards an understanding of phase transitions between inverse bicontinuous cubic lyotropic liquid crystalline phases. Soft Matter, 2010, 6, 256-262. G.C. Shearman, A.I.I. Tyler, N.J. Brooks, R.H. Templer, O. Ces, R.V. Law, J.M. Seddon, A 3-D hexagonal inverse micellar lyotropic phase. J. Am. Chem. Soc., 2009, 131(5), 1678-1679. G.C. Shearman, S. Ugazio, L. Soubiran, J. Hubbard, O. Ces, J.M. Seddon, R.H. Templer, Factors controlling the stability of a kinetically hindered lamellar-lamellar transition. J. Phys. Chem. B, 2009, 113(7), 1948-1953. G.C. Shearman, S. Ugazio, L. Soubiran, J. Hubbard, O. Ces, J.M. Seddon, R.H. Templer, The lyotropic phase behaviour of ester quaternary surfactants. J. Coll. Interface Sci., 2009, 331(2), 463-469. G.C. Shearman, G. Yahioglu, J. Kirstein, L.R. Milgrom, J.M. Seddon, Synthesis and phase behaviour of ?-octaalkyl porphyrins. J. Mat. Chem., 2009, 19(5), 598-604. D.P. Lydon, D. Albesa-Jove, G.C. Shearman, J.M. Seddon, J.A.K. Howard, T.B. Marder, P.J. Low, The synthesis and liquid crystalline behaviour of alkoxy-substituted derivatives of 1,4-bis(phenylethynyl)benzene. Liq. Cryst., 2009, 35(2), 119-132. D.R. Casey, S.C. Sebai, G.C. Shearman, O. Ces, R.V. Law, R.H. Templer, A.D. Gee, Formulation affects the rate of membrane degradation catalyzed by cationic amphiphilic drugs. Ind. Eng. Chem. Res., 2008, 47(3), 650-655. G.C. Shearman, B.J. Khoo, M.-L. Motherwell, K.A. Brakke, O. Ces, C.E. Conn, J.M. Seddon, R.H. Templer, Calculations of and evidence for chain packing stress in inverse lyotropic bicontinuous cubic phases. Langmuir, 2007, 23(13), 7276-7285. G.C. Shearman, G.S. Attard, A.N. Hunt, S. Jackowski, M. Baciu, S.C. Sebai, X. Mulet, J.A. Clarke, R.V. Law, C. Plisson, C.A. Parker, A. Gee, O. Ces, R.H. Templer, Using membrane stress to our advantage. Biochem. Soc. Trans., 2007, 35(3), 498-501. M. Baciu, S.C. Sebai, O. Ces, X. Mulet, J.A. Clarke, G.C. Shearman, R.V. Law, R.H. Templer, C. Plisson, C.A. Parker, A. Gee, Degradative transport of cationic amphiphilic drugs across phospholipid bilayers. Phil. Trans. R. Soc. A, 2006, 364(1847), 2597-2614. J.M. Seddon, A.M. Squires, C.E. Conn, O. Ces, A.J. Heron, X. Mulet, G.C. Shearman, R.H. Templer, Pressure-jump X-ray studies of liquid crystal transitions in lipids. Phil. Trans. R. Soc. A, 2006, 364(1847), 2635-2655. G.C. Shearman, O. Ces, R.H. Templer, J.M. Seddon, Inverse lyotropic phases of lipids and membrane curvature. J. Phys. Condens. Matter, 2006, 18(28), S1105-S1124. D.S. Valkovska, G.C. Shearman, C.D. Bain, R.C. Darton, J. Eastoe, Adsorption of ionic surfactants at an expanding air-water interface. Langmuir, 2004, 20(11), 4436-4445. T. Battal, G.C. Shearman, D. Valkovska, C.D. Bain, R.C. Darton, J. Eastoe, Determination of the dynamic surface excess of a homologous series of cationic surfactants by ellipsometry. Langmuir, 2003, 19(4), 1244-1248.