Dr. Jeff Siewerdsen directs the Carnegie Center and oversees activities relating to research, engineering education, and device innovation / translation. He is Professor of Biomedical Engineering and head of the I-STAR Lab with primary research interests in 3D image quality and cone-beam CT applications in diagnostic and image-guided procedures. He leads a program of interdisciplinary research spanning projects in medical imaging physics, image registration, and image-guided interventions, with a focus on advanced x-ray CT and spectral imaging modalities, the mathematics of image quality, the design of novel imaging systems, and 3D deformable image registration.

Among the most challenging and exciting topics in medical imaging research is the development of advanced imaging technologies for guiding therapeutic procedures. With applications ranging from radiation therapy to interventional procedures and surgery, the importance of bringing high-performance imaging into the arena of therapy is clear. The development of such novel technologies, however, raises a number of critical research questions, ranging from issues of basic image science to integration with the therapeutic procedure. These questions are at the heart of the projects carried out in the laboratories of Dr. Siewerdsen’s group, encompassing a broad range of topics targeted toward the development and rapid deployment of innovative imaging technologies for therapy guidance. Central to Dr. Siewerdsen’s research are issues of basic imaging physics, quantitative description of multi-dimensional imaging performance and imaging task, and the development of novel multidimensional imaging technologies.