Dr. David Moller is a professor of medicine at the Johns Hopkins University School of Medicine. His areas of clinical expertise include pulmonary and critical care medicine, with a particular focus on sarcoidosis. Dr. Moller serves as the director of the Sarcoidosis Clinic at Johns Hopkins. Dr. Moller earned his M.D. from the Tufts University School of Medicine. He completed his residency at the University of Cincinnati College of Medicine. He performed a fellowship in allergy and clinical immunology at the University of Cincinnati College of Medicine and a fellowship in pulmonary medicine at the National Institutes of Health. Dr. Moller’s research interests include pulmonary fibrosis, sarcoidosis and granulomatous lung disease.

Pulmonary fibrosis; Sarcoidosis; Granulomatous lung disease

Dr. Moller’s research focuses on sarcoidosis. He was the senior investigator on a project that identified a possible protein trigger responsible for sarcoidosis, a potentially fatal inflammatory disease marked by tiny clumps of inflammatory cells that each year leave deep, grainy scars on the lungs, lymph nodes, skin and almost all major organs in hundreds of thousands of Americans. He is currently coordinating two clinical trials at Johns Hopkins—one related to genomic research in sarcoidosis and one related to genomic research in Alpha-1 antitrypsin deficiency.

Moller DR, Koth LL, Maier LA, Morris A, Drake W, Rossman M, Leader JK, Collman RG, Hamzeh N, Sweiss NJ, Zhang Y, O'Neal S, Senior RM, Becich M, Hochheiser HS, Kaminski N, Wisniewski SR, Gibson KF; GRADS Sarcoidosis Study Group. "Rationale and Design of the Genomic Research in alpha-1 antitrypsin deficiency and sarcoidosis (GRADS) study. Sarcoidosis Protocol." Ann Am Thorac Soc. 2015 Oct;12(10):1561-71. doi: 10.1513/AnnalsATS.201503-172OT. Chen ES, Moller DR. "Etiologies of sarcoidosis." Clin Rev Allergy Immunol. 2015 Aug;49(1):6-18. doi: 10.1007/s12016-015-8481-z. PMID: 25771769 Moller DR. "Negative clinical trials in sarcoidosis: failed therapies or flawed study design?" Eur Respir J. 2014 Nov;44(5):1123-6. doi: 10.1183/09031936.00156314. No abstract available. PMID: 25362122 Chen ES, Moller DR. "Etiologic role of infectious agents." Semin Respir Crit Care Med. 2014 Jun;35(3):285-95. doi: 10.1055/s-0034-1376859. Epub 2014 Jul 9. Review. PMID: 25007081 Muller-Quernheim J, Prasse A, Moller DR. "Sarcoidosis: recent advances." Semin Respir Crit Care Med. 2014 Jun;35(3):283-4. doi: 10.1055/s-0034-1376864. Epub 2014 Jul 9. No abstract available. Zhou T, Zhang W, Sweiss NJ, Chen ES, Moller DR, Knox KS, Ma SF, Wade MS, Noth I, Machado RF, Garcia JG. Peripheral blood gene expression as a novel genomic biomarker in complicated sarcoidosis. PLoS One. 2012;7(9):e44818. doi: 10.1371/journal.pone.0044818. Epub 2012 Sep 12. PMID: 22984568 Brandstrup B, Svendsen PE, Rasmussen M, Belhage B, Rodt SA, Hansen B, Moller DR, Lundbech LB, Andersen N, Berg V, Thomassen N, Andersen ST, Simonsen L. Which goal for fluid therapy during colorectal surgery is followed by the best outcome: near-maximal stroke volume or zero fluid balance? Br J Anaesth. 2012 Aug;109(2):191-9. doi: 10.1093/bja/aes163. Epub 2012 Jun 17. PMID: 22710266 Sweiss NJ, Zhang W, Franek BS, Kariuki SN, Moller DR, Patterson KC, Bennett P, Girijala LR, Nair V, Baughman RP, Garcia JG, Niewold TB. Linkage of type I interferon activity and TNF-alpha levels in serum with sarcoidosis manifestations and ancestry. PLoS One. 2011;6(12):e29126. doi: 10.1371/journal.pone.0029126. Epub 2011 Dec 14. PMID: 22195005 Chen ES, Moller DR. Sarcoidosis--scientific progress and clinical challenges. Nat Rev Rheumatol. 2011 Jul 12;7(8):457-67. doi: 10.1038/nrrheum.2011.93. Review. PMID: 21750528