Xiang, Jialing
Professor
个人简介
M.D. Xuzhou Medical University Ph.D. University of Alabama at Birmingham
近期论文
Zhang H, Lin Y, Manas A, Zhao Y, Denning MF, Ma L, Xiang, J. (2014) Bax?2 promotes apoptosis through caspase-8 activation in microsatellite unstable colon cancer. Mol. Cancer Res. 12(9), 1225-23. Haferkamp, B., Zhang, H., Kissinger, S., Xin, W., Lin, Y., Schultz, M., Xiang, J. (2013) BaxΔ2 family alternative splicing salvages Bax microsatellite-frameshift mutations. Genes & Cancer. 4, 501-512. Yan, J., Xiang, J., Lin, Y., Ma, J., Zhang, J., Zhang, H., Sun, J., Danial, N., Liu, J., Lin, A. (2013). Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation. Cell. 152(1), 304-315. Lin, Y., Lu, Z., Kokontis, J., Xiang, J. (2013). Androgen receptor primes prostate cancer cells to apoptosis through down-regulation of basal p21 expression. Biochem. Biophys. Res. Commun. 430(1), 289-93. Haferkamp, B., Zhang, H., Lin, Y., Yeap. X, Bounce, A., Sharpe, J., Xiang, J. (2012). BaxΔ2 is a novel Bax isoform unique to microsatellite unstable tumors. J. Biol. Chem. 287(41), 34722-9. Godfrey, B., Lin, Y., and Xiang, J. (2010). Structure and function analysis of the pro-death domains of androgen receptor in prostate cancer cells. Cell Res. 20: 1138-1140. Tang F, Kokontis J, Lin Y, Liao S, Lin A, Xiang, J. (2009).Androgen via p21 inhibits TNF-alpha-induced JNK activation and apoptosis. J. Biol. Chem. 284(47), 32353-8. Deng, H., Yu, F., Chen, J., Zhao, Y., Xiang, J., Lin, A. (2008). Phosphorylation of bad at Thr201 by JNK1 promotes glycolysis through activation of phosphofructokinase-1. J. Biol.Chem. 283(30):20754-60. Lin, Y., Fukuchi, J., Hiipakka, R., Kokontis, J., and Xiang, J. Up-regulation of Bcl-2 is required for the progression of prostate cancer cells from androgen-dependent to androgen-independent growth. Cell Res. 17(6), 531-536 (2007). Lin, Y., Kokontis, J., Tang, F., Liao, S., Lin, A., Chen, C., and Xiang, J. Androgen and Its Receptor AR Promote BAX-mediated Apoptosis. Mol. Cell. Biol. 26(5), 1908 –1916 (2006). Yu, C., Minemoto, Y., Zhang, J., Liu, J., Tang, F., Bui, T., Lin, A.* and Xiang, J*. Activation of the JNK pathway inhibits IL-3 withdrawal induced apoptosis in B-lymphocytes. Molecular Cell. 13, 329-340 (2004). Xiang, J., Gomez-Navarro, J, Arafat, W., Liu B., Barker, S.D., Alvarez, R.D., Siegal G.P., and Curiel, D.T. Pro-apoptotic treatment with an adenovirus encoding bax enhances the effect of chemotherapy in ovarian cancer. J. Gene Medicine 2(2), 97-106 (2000). Xiang, J., Chao, D.T., and Korsmeyer, S.J. Bax-induced cell death may not require interleukin 1 b-converting enzyme-like proteases. Proc. Natl. Acad. Sci. USA. 93, 14559-14563 (1996).