Organic Chemistry and Catalysis

The research interest of our group is focussed on the chemistry of transition metal complexes and their use as catalysts for organic reactions. We investigate the reactivity of transition metal compounds with the aim of elucidating and understanding the elementary steps of a catalytic cycle. With this mechanistic knowledge we try to improve existing catalytic processes and develop new synthetically useful catalytic reactions. We are particularly interested in the functionalization of unactivated C-H bonds and the reactivity of low-ligated complexes. Our work touches on inorganic as well as organic chemistry, ranging from the synthesis of new ligands, isolation of sensitive organometallic compounds to kinetic measurements.

F.D. Sypaseuth, C. Matlachowski, M. Weber, M. Schwalbe, C.C. Tzschucke Electrocatalytic Carbon Dioxide Reduction by Using Cationic Pentamethylcyclopentadienyl-Iridium Complexes with Unsymmetrically Substituted Bipyridine Ligands Chem. Eur. J. 2015, doi: 10.1002/chem.201404367 M.S. Andrä, C.C. Tzschucke Short Convergent Synthesis of Locked Retinals Eur. J. Org. Chem. 2014, 7265–7272 K. Neuthe, H. Brandt, A. Hinsch, C.C. Tzschucke, W. Veurman, B. Ziem, R. Haag SCN free vs. SCN containing dyes for TiO2 based dye sensitized solar cells ChemElectroChem 2014, 1, 1656–1661 D. Könning, T. Olbrisch, F.D. Sypaseuth, C.C. Tzschucke, M. Christmann Oxidation of Allylic and Benzylic Alcohols to Aldehydes and Carboxylic Acids Chem. Commun. 2014, 50, 5014-5016 S. Liu, D. Lentz, C.C. Tzschucke Conversion of Pyridine N-Oxides to Tetrazolopyridines J. Org. Chem. 2014, 79, 3249–3254 S. Duric, F. D. Sypaseuth, S. Hoof, E. Svensson, C.C. Tzschucke Synthesis of Asymmetrically Substituted Terpyridines by Palladium-Catalyzed Direct C-H-Arylation of Pyridine N-Oxides Chem. Eur. J. 2013, 19, 17456-17463 T. Rossow, S. Bayer, R. Albrecht, C.C. Tzschucke, S. Seiffert Supramolecular Hydrogel Capsules Based on PEG: A Step Toward Degradable Biomaterials with Rational Design Macromol. Rapid Commun. 2013, 34, 1401-1407 M. Hapke, C.C. Tzschucke Achieving Enantioselectivity with Chiral Cyclopentadienylrhodium Complexes Angew. Chem. 2013, 125, 3399-3401; Angew. Chem. Int. Ed. 2013, 52, 3317-3319. S. Duric, B.M. Schmidt, N.M. Ninnemann, D. Lentz, C.C. Tzschucke Synthesis of Trifluorostyrene Derivatives by Palladium-Catalyzed Cross-Coupling of Lithium Trimethoxy(trifluorovinyl)borate with Aryl Bromides

Chem. Eur. J. 2012, 18, 437-441.