PhD, Cornell University, 2002

All biological events, such as cell signaling and gene regulation are accomplished by biomacromolecular complexes. I am interested in dissecting these complexes to develop a fundamental understanding of the formation and regulation of these biological machineries. Such studies are critical to the success of identifying drug targets and developing potential therapeutics.

Interaction between the T4 Helicase Loading Protein (gp59) and the DNA Polymerase (gp43): Unlocking of the gp59-gp43-DNA Complex to Initiate Assembly of A Fully Functional Replisome. (2005) Biochemistry 44, 7747-56.

Interaction between the T4 helicase-loading protein (gp59) and the DNA polymerase (gp43): a locking mechanism to delay replication during replisome assembly. (2005) Biochemistry 44, 2305-2318.