Rovis, Tomislav 照片

Rovis, Tomislav

Professor

所属大学: Columbia University

所属学院: Department of Chemistry

邮箱:
tr2504@columbia.edu

个人主页:
https://www.chem.columbia.edu/content/tomislav-rovis

个人简介

2016-present Professor Department of Chemistry, Columbia University, New York, NY 2013 Chair, Organometallic Chemistry Directed Towards Organic Synthesis (OMCOS 17)July 28-August 1, 2013 - Fort Collins, CO 2012-2018 Permanent Member, Synthetic and Biological Chemistry B Study Section, NIH (SBC-B) 2012-present Associate Editor for the Americas, Synlett 2010-2015 Member, Editorial Board, Organic Reactions 2010-present Member, Editorial Board, electronic Encyclopedia of Reagents for Organic Synthesis 2008-2016 John K. Stille Chair Department of Chemistry, Colorado State University, Fort Collins, CO 2008-2016 Professor Department of Chemistry, Colorado State University, Fort Collins, CO 2005-2008 Associate Professor Department of Chemistry, Colorado State University, Fort Collins, CO 2000-2005 Assistant Professor Department of Chemistry, Colorado State University, Fort Collins, CO 1998-2000 NSERC Post-Doctoral Research Fellow Harvard University, Cambridge, Massachusetts with Prof. David A. Evans 1993-1998 Ph.D. Organic Chemistry University of Toronto, Toronto, Ontario with Prof. Mark Lautens 1986-1990 B.Sc. Human Biology University of Toronto, Toronto, Ontario

研究领域

Over the course of the past greater decade, our research here at the Rovis group has covered a broad range of topics in asymmetric catalysis, organocatalysis, and organometallic chemistry. Since its inception, our group has disclosed findings ranging from the stereoselective rearrangements of vinyl acetals and ethers, to Ni-catalyzed desymmetrizations of various cyclic meso-anhydrides, and even disclosing the synthesis of several natural products using various technologies developed within the lab. We also have a rich and prominent history within the field of N-heterocyclic carbenes (NHCs) as organocatalysts, pioneering studies in acyl-anion, azolium-enolate, and homoenolate reactivities as catalyzed by triazolylidene-based carbenes. We use the methodology developed within our group to provide easier access to nitrogen and oxygen containing heterocycles, those of which are of significant interest to the fields of medicinal chemistry and pharmaceutical development.

近期论文

Late-Stage N-Me Selective Arylation of Trialkylamines Enabled by Ni/Photoredox Dual Catalysis Yangyang Shen and Tomislav Rovis* J. Am. Chem. Soc. 2021, 143, 40, 16364–16369 Rh(III)-Catalyzed Three-Component Syn-Carboamination of Alkenes Using Arylboronic Acids and Dioxazolones Sumin Lee and Tomislav Rovis* ACS Catal. 2021, 11, 14, 8585–8590 Copper Catalyzed C(sp3)–H Bond Alkylation via Photoinduced Ligand-to-Metal Charge Transfer Sean M. Treacy and Tomislav Rovis* J. Am. Chem. Soc. 2021, 143, 7, 2729–2735 Development of a Platform for Near-Infrared Photoredox Catalysis Benjamin D. Ravetz, Nicholas E. S. Tay, Candice L. Joe*, Melda Sezen-Edmonds, Michael A. Schmidt, Yichen Tan, Jacob M. Janey, Martin D. Eastgate, and Tomislav Rovis* ACS Cent. Sci. 2020, 6, 11, 2053–2059 Photoredox-Catalyzed Deaminative Alkylation via C–N Bond Activation of Primary Amines Melissa A. Ashley, Tomislav Rovis J. Am. Chem. Soc. 2020, 142, 43, 18310–18316 A site-selective amination catalyst discriminates between nearly identical C–H bonds of unsymmetrical disubstituted alkenes Honghui Lei, Tomislav Rovis Nat. Chem. 2020, 12, 725-731 Direct Regio‐ and Diastereoselective Synthesis of δ ‐Lactams from Acrylamides and Unactivated Alkenes Initiated by Rh(III)‐Catalyzed C−H Activation Sumin Lee, Natthawat Semakul, Tomislav Rovis Angew. Chem. Int. Ed. 2020, 59 , 4965. Ligand Controlled Ir-Catalyzed Regiodivergent Oxyamination of Unactivated Alkenes Honghui Lei, John H. Conway Jr., Caleb C. Cook, and Tomislav Rovis J. Am. Chem. Soc. 2019, 141, 30, 11864-11869 Rh(III)-Catalyzed C-H Activation-Initiated Directed Cyclopropanation of Allylic Alcohols Erik J. T. Phipps and Tomislav Rovis J. Am. Chem. Soc. 2019, 141, 6807-6811 Asymmetric delta-Lactam Synthesis with a Monomeric Streptavidin Artificial Metalloenzyme Isra S. Hassan, Angeline N. Ta, Michael W. Danneman, Natthawat Semakul, Matthew Burns, Corey H. Basch, Vanessa N. Dippon, Brian R. McNaughton, and Tomislav Rovis J. Am. Chem. Soc. 2019, 141, 4815-4819 Photoredox catalysis using infrared light via triplet fusion upconversion Benjamin D. Ravetz, Andrew B. Pun, Emily M. Churchill, Daniel N. Congreve, Tomislav Rovis & Luis M. Campos Nature. 2019, 565, 343-346