BA, Longwood College, 1992 PhD, Virginia Commonwealth University, 1997 Postdoctoral, Iowa State University, 1998

Analytical Chemistry/Biochemistry/Biophysical Chemistry/Materials/Medicinal Chemistry/Bio-Inorganic Chemistry/Electrochemistry

Research focuses on the modification of electrode surfaces with biological molecules for both sensing and fundamental studies. Current areas of interest include electrochemical detection of cholesterol efflux from the cell plasma membrane (in vivo and in vitro) and microfluidic electrochemical sensor platforms.

Fang, D., Jiang, D., Lu, H., Chiel, H. J., Kelley, K. J., Burgess, J. D. “Observation of Cellular Cholesterol Efflux at Microcavity Electrodes” J. Am. Chem. Soc. 2009, 131, 12038-12039. Jiang, D. C., Fang, D.J., Kelley, T. J., Burgess J. D. “Electrochemical Analysis of Cell Plasma Membrane Cholesterol at the Airway Surface of Mouse Trachea” Anal. Chem. 2008, 80: 1235–1239. Jiang, D., Devadoss, A., Palencsár, S., Fang, D., White, N. M., Kelley, T. J., Smith, J. D., Burgess, J. D.. “Direct Electrochemical Evaluation of Plasma Membrane Cholesterol in live Mammalian Cells” J. Am. Chem. Soc. 2007, 129: 11352-11353. Devadoss, A., Palencsár, S. M., Jiang, D., Honkonen, M. L., Burgess, J. D. “Microelectrode Detection of Cholesterol in Vesicle Lipid Bilayer Membranes” Anal. Chem. 2005, 77: 7393-7398. Devadoss, A., Burgess, J. D. “Steady-State Detection of Cholesterol Contained in the Plasma Membrane of a Single Cell Using Lipid Bilayer-Modified Microelectrodes Incorporating Cholesterol Oxidase.” J. Am. Chem. Soc. 2004, 126: 10214-10215. Bokoch, M. P., Devadoss, A., Palencsár, M. S., Burgess, J. D. “Steady-State Oxidation of Cholesterol Catalyzed by Cholesterol Oxidase in Lipid Bilayer Membranes on Platinum Electrodes.” Analytica Chimica Acta. 2004, 519: 47-55. Devadoss, A., Burgess, J. D. “Detection of Cholesterol through Electron Transfer to Cholesterol Oxidase in Electrode-Supported Lipid Bilayer Membranes.” Langmuir. 2002, 18: 9617-9621.

Wang, Y., Farrell, N., Burgess, J. D. “Direct Evidence for Preassociation Preceding Covalent Binding in the Reaction of cis-[Pt(NH3)2(H2O)2]2+ with Surface Immobilized Oligonucleotides.” J. Am. Chem. Soc. 2001, 123: 5576-5577.