Investigation of the involvement of pathological substances including bile, alcohol and non-oxidative alcohol metabolites in the initiation of acute pancreatitis. Physiological calcium signalling in pancreatic acinar cells including actions of nicotinic acid adenine dinucleotide phosphate (NAADP) and its role in physiology and pathology of exocrine pancreas. Development of two-photon microscopy applications for studies of exocrine pancreas

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