PhD, University of Buenos Aires, Argentina MSc, University of Buenos Aires, Agentina

Molecular genetics of mechanisms that contribute to the virulence pathogenic bacteria

K. Chiem, S. Jani, B. Fuentes, D. L. Lin, M. E. Rasche, and M. E. Tolmasky. Identification of an inhibitor of the aminoglycoside 6’-N-acetyltransferase type Ib [AAC(6′)-Ib] by Glide molecular docking. MedChemComm 2016 216 184-189. doi: 10.1039/c5md00316d. K. Chiem, B. Fuentes, D. L. Lin, Tran, T., A. Jackson, M. S,. Ramirez, and M. E. Tolmasky. Inhibition of of aminoglycoside 6'-N-acetyltransferase type Ib-mediated amikacin resistance in Klebsiella pneumoniae by zinc and copper pyrithione. Antimicrobial Agents and Chemotherapy 2015 59 5851-5853. doi: 10.1128/AAC.01106-15. PMID: 26169410 C. Lopez, B. Arivett, L. A. Actis, and M. E. Tolmasky. Inhibition of AAC(6')-Ib-mediated resistance to amikacin in Acinetobacter baumannii by an antisense peptide-conjugated 2',4'-bridged nucleic acid-NC-DNA hybrid oligomer. Antimicrobial Agents and Chemotherapy 2015 59 5798-5803. doi: 10.1128/AAC.01304-15. PMID: 26169414 C. Davies Sala, A. J. C. Soler Bistué, R. Bonomo, A. Zorreguieta, and M. E. Tolmasky. External Guide Sequence (EGS) technology: a path to development of novel antimicrobial therapeutics. Annals of the New York Academy of Sciences 2015 1354 98-110. doi: 10.1111/nyas.12755. PMID: 25866265 G. Traglia, C. Dixon, K. Chiem, M. Almuzara, C. Barberis, S. Monta?a, C. Merino, M. Mussi, M. E. Tolmasky, A. Iriarte, C. Vay, and M. S. Ramirez. Draft Genome Sequence of Empedobacter falsenii comb. nov. (ex-Wautersiella falsenii) Wf282, a strain isolated from a cervical neck abscess. Genome Announcements 2015 3 e00235-15. doi: 10.1128/genomeA.00235-15. PMID: 25838490 J. Lin, K. Nishino, M. Roberts, D. Centron, M. E. Tolmasky, R. Aminov, and L. Zhang. Mechanisms of antibiotic resistance. Frontiers in Microbiology 2015 6 34. doi: 10.3389/fmicb.2015.00034. PMID: 25699027 B. Arivett, S. Fiester, D. Ream, D. Centron, M. S. Ramirez, M. E. Tolmasky, and L. A. Actis. Draft genome of the multidrug-resistant Acinetobacter baumannii A155 clinical isolate. Genome Announcements 2015 3 e00212-15. doi: 10.1128/genomeA.00212-15. PMID: 25814610