PhD, Stanford University BS, Massachusetts Institute of Technology

Molecular mechanisms of Notch receptor signaling by typical and atypical ligands; developmental and cell biology of elastic fiber proteins

Nichols, J.T., Miyamoto, A. , Olsen, S.L., D’Souza, B., Yao, C., Weinmaster, G. (2007) DSL-ligand endocytosis physically dissociates Notch1 heterodimers prior to activating proteolysis.J. Cell Biol. 176 :445-458. D'Souza, B., Miyamoto, A ., and Weinmaster, G. (2008) The many facets of Notch ligands.Oncogene . 27 (38):5148-67. Miyamoto, A. and Weinmaster, G. (2008) Introduction to Notch signaling (Chapter 54). In C. J. Epstein, R. P. Erickson and A. Wynshaw-Boris (Eds.), Molecular Basis of Inborn Errors of Development , 2nd edition. New York, New York: Oxford University Press. Miyamoto, A. and Weinmaster, G. (2008) Notch signal transduction: Molecular and cellular mechanisms. In L. R. Squire (Ed.), Encyclopedia of Neuroscience . Oxford, UK: Academic Press. Nichols, J.T., Miyamoto, A. , and Weinmaster, G. (2007) Notch: constantly on the move.Traffic 8 :959-69. Miyamoto, A. , *Lau, R., Hein, P.W., Shipley, J.M., Weinmaster, G. (2006) Microfibrillar proteins MAGP-1 and MAGP-2 induce Notch1 extracellular domain dissociation and receptor activation. J. Biol. Chem . 281 :10089-97.