Ph.D. in Organic Chemistry, The Scripps Research Institute, Florida M.S. in Organic Chemistry, Brown University B.S. in Organic Chemistry, Nanjing University

My research will mainly focus on Synthetic Organic Chemistry, specifically in the areas of asymmetric catalysis with transition-metal complexes and total syntheses of bioactive natural products.

Jichao Chen, Evangelos Miliordos, Ming Chen*, “Highly Diastereo- and Enantioselective Synthesis of 3,6’-Bisborylanti-1,2-oxaborinan-3-enes: An Entry to Enantioenriched Homoallylic Alcohols with A Stereodefined Trisubstituted Alkene,” Angew. Chem. Int. Ed. 2021, 60, 840. Shang Gao, Meng Duan, Qianzhen Shao, K. N. Houk*, Ming Chen*, “Development of α,α-Disubstituted Crotylboronate Reagents and Stereoselective Crotylation via Brønsted or Lewis Acid Catalysis,” J. Am. Chem. Soc. 2020, 142, 18355. Shang Gao, Meng Duan, K. N. Houk*, Ming Chen*, "Chiral Phosphoric Acid Dual‐Function Catalysis: Asymmetric Allylation with α‐Vinyl Allylboron Reagents," Angew. Chem. Int. Ed. 2020, 59, 10540. Jiaming Liu, Ming Chen*,"Enantioselective anti- and syn-(Borylmethyl)allylation of Aldehydes via Brønsted Acid Catalysis," Org. Lett. 2020, 22, 8967. Jichao Chen, Ming Chen*, “Enantioselective Syntheses of (Z)-6’-Boryl-anti-1,2-oxaborinan-3-enes via a Dienylboronate Protoboration and Asymmetric Allylation Reaction Sequence,” Org. Lett. 2020, 22, 7321. Shang Gao, Ming Chen*, "Enantioselective Syntheses of 1,4-Pentadien-3-yl Carbinols via Brønsted Acid Catalysis," Org. Lett. 2020, 22, 400. Jiaming Liu, Xinbo Tong, Ming Chen*, "Allylboration of Ketones and Imines with a Highly Reactive Bifunctional Allyl Pinacolatoboronate Reagent," J. Org. Chem. 2020, 85, 5193. Jichao Chen, Shang Gao, Ming Chen*, “Cu-Catalyzed C-C Bond Formation of Vinylidene Cyclopropanes with Carbon Nucleophiles,” Chem. Sci. 2019, 10, 10601. Shang Gao, Ming Chen*, “alfa-Silicon Effect Assisted Curtin-Hammett Allylation Using Allylcopper Reagents Derived from 1,3-Dienylsilanes,” Chem. Sci. 2019, 10, 7554. Shang Gao, Jichao Chen, Ming Chen*, “(Z)-α-Boryl-crotylboron Reagents via Z-Selective Alkene Isomerization and Application to Stereoselective Syntheses of (E)-δ-Boryl-syn-homoallylic Alcohols,” Chem. Sci. 2019, 10, 3637. Shang Gao, Ming Chen*, “Catalytic Carboboration of Dienylboronate for Stereoselective Synthesis of (E)-γ’,δ-Bisboryl-anti-Homoallylic Alcohols,” Chem. Commun. 2019, 11199. Jichao Chen, Shang Gao, Ming Chen*, “Stereoselective Syntheses of γ,δ-Bifunctionalized Homoallylic Alcohols and Ethers via Chemoselective Allyl Addition to Aldehydes,” Org. Lett. 2019, 21, 9893. Jichao Chen, Shang Gao, Ming Chen*, “Cu-Catalyzed Vinylidene Cyclopropane Borylation and Silylation for the Syntheses of Propargylic Silane and Boron Compounds,” Org. Lett. 2019, 21, 8800. Mengzhou Wang, Shang Gao, Ming Chen*, “Stereoselective Syntheses of (E)-γ’,δ-Bisboryl Substituted syn-Homoallylic Alcohols via Chemoselective Aldehyde Allylboration,” Org. Lett. 2019, 21, 2151. Jichao Chen, Shang Gao, Ming Chen*, “Stereoselective Syntheses of γ-Boryl Substituted syn-β-Alkoxy- and syn-β-Amino-homoallylic Alcohols via a Regio- and Stereoselective Allene Diboration and Aldehyde Allylboration Reaction Sequence,” Org. Lett. 2019, 21,4638. Jiaming Liu, Shang Gao, Ming Chen*, "Preparation of Bifunctional Allylboron Reagent and Application to Aldehyde Allylboration," Org. Process Res. Dev. 2019, 23, 1659 (Invited contribution honoring 25 years of the Buchwald-Hartwig amination). Jiaming Liu, Shang Gao, Ming Chen*, “Enantioselective Syntheses of (E)-γ,δ-Disubstituted Homoallylic Alcohols via BF3OEt2-Catalyzed Aldehyde Allylboration and Analysis of the Origin of E-selectivity: A1,2 Allylic Strain vs. syn-Pentane Interaction,” Tetrahedron 2019, 75, 4110 (Invited contribution in honor of Professor John Hartwig for his 2019 Tetrahedron Prize). Shang Gao, Mengzhou Wang, Ming Chen*, “Syntheses of Unsymmetrical 1,4-Bifunctional Allylboron Reagents via Cu-Catalyzed Highly Regio- and Stereoselective 1,4-Protoboration of Dienylboronates and Analysis of the Origin of Chemoselective Aldehyde syn-(Hydroxymethyl)allylation,”Org. Lett. 2018, 20, 7921. Shang Gao, Ming Chen*, “Enantioselective syn- and anti-Alkoxyallylation of Aldehydes via Brønsted Acid Catalysis,” Org. Lett. 2018, 20, 6174. Mengzhou Wang, Shahriar Khan, Evangelos Miliordos, Ming Chen*, “Enantioselective Allenylation of Aldehydes via Brønsted Acid Catalysis,” Adv. Synth. Catal. 2018, 360, 4634. Mengzhou Wang, Shahriar Khan, Evangelos Miliordos, Ming Chen*, “Enantioselective Syntheses of Homopropargylic Alcohols via Asymmetric Allenylboration,” Org. Lett. 2018, 20, 3810.