Worthington, Tony 照片

Worthington, Tony

Dr

所属大学: Aston University

所属学院: School of Life & Health Sciences, Biology/Biosciences

邮箱:
T.Worthington@aston.ac.uk

个人主页:
http://www.aston.ac.uk/lhs/staff/az-index/wortht/

个人简介

2014-present: Reader in Clinical Microbiology and Infectious Disease, Aston University 2008-2014: Senior Lecturer in Clinical Microbiology and Infectious Disease, Aston University 2004-2008: Lecturer in Clinical Microbiology, Aston University 2000 PhD (Medical Microbiology), Aston University 1999-2004 Senior Clinical Research Scientist. Clinical Microbiology and Infection Control, University Hospital Birmingham NHS Trust 1991-1999 Senior Biomedical Scientist. Clinical Microbiology and Infection Control, University Hospital Birmingham NHS Trust 1990 Fellowship of the Institute of Biomedical Sciences (FIBMS), (specialising in Medical Microbiology) 1988: George Randall Memorial Award (Medical Microbiology) 1985-1991 Biomedical Scientist Microbiology, PHLS, Heartlands Hospital, Birmingham

研究领域

Clinical Microbiology and Healthcare Associated Infection (diagnosis, treatment and prevention of infection) Propionibacterium acnes and its association with chronic lower back pain and type 1 Modic changes Clostridium difficile and Staphylococcal Infections Biofilms; infections associated with indwelling intravascular devices and prosthetic joints Skin Antisepsis and Antimicrobials

近期论文

Lambert P, Elliott T, Worthington T, Vernallis A, Rollason J. Letter to the Editor concerning "Prospective study using anterior approach did not show association between Modic 1 changes and low grade infection in lumbar spine" by Rigal J, et al.: Eur Spine J; 2016 Apr; 25(4):1000-5. Lambert P, Elliott T, Worthington T, Vernallis A, Rollason J. Letter to the Editor concerning "Prospective study using anterior approach did not show association between Modic 1 changes and low grade infection in lumbar spine" by Rigal J, et al.: Eur Spine J; 2016 Apr; 25(4):1000-5. Elliott TSJ, Casey AL, Karpanen TJ, David MD, Whitehouse T, Lambert PA, Vernallis AB, Worthington T, Parekh G, Dunstan CR, Kirby J, Davis P. Addition of PLA2 to CRP enhances sepsis diagnosis. J Infect (2016). http://dx.doi.org/10.1016/j.jinf.2016.07.009 (online) Worthington T and Hilton A. Sporulation of Clostridium difficile in areobic conditions is significantly protracted when exposed to sodium taurocholate. (2016). J Med Microb Diag;5(2).doi.10.4172/2161-0703.1000230 (online) Begum S, Johnson EW, Worthington T, Martin RA. (2016). The influence of pH and fluid dynamics on the antibacterial efficacy of 45S5 Bioglass. Biomedical Materials; 11:1-9 (online). Rollason, J., McDowell, A., Albert, H.B., Barnard, E., Worthington, T., Hilton, A.C., Vernallis, A., Patrick, S., Elliott, T., and Lambert, P. (2013) 'Genotypic and antimicrobial characterisation of Propionibacterium acnes isolates from surgically excised lumbar disc herniations'. BioMed Research International. (online) Albert HB, Lambert P, Rollason J, Sorensen JS, Worthington T, Pedersen MB, N?rgaard HS, Vernallis A, Busch F, Manniche C, Elliott T. Does nuclear tissue infected with bacteria following disc herniation lead to Modic changes in the adjacent vertebrae. Eur Spine J. 2013;22(4):690-6. doi: 10.1007/s00586-013-2674-z.. (online) Hendry E, Conway B, Worthington T. Digluconate and isopropyl biocide formulation. Int J Mol Sci. 2012 Oct 30;13(11):14016-25. doi: 10.3390/ijms131114016 (online) El Shaer A, Hanson P, Worthington T, Lambert PA, Mohammed AR. Preparation and Characterisation of Amino Acids Based Trimethoprim Salts (2012). Pharmaceutics; 4: 179-196. Worthington T, Karpanen T, Casey A, Lambert PA, Elliot TS. Self-Disinfecting Surfaces: Reply to Weber and Rutala (2012). The Society for Healthcare Epidemiology of America (SHEA): 33(5); 645-646. Worthington T. The World of Microbiology Goes to Kenya. Hakuna Matata. Microbiologist (2012);12-15 (online) Green LM, Worthington T, Hilton AC, Lambert PA. Genetic characterisation of clinical isolates of Clostridium difficile using an optimised RAPD protocol and PCR ribotyping reveals strain diversity between two tertiary referral Trusts in the West Midlands, UK.J Med Microbiol. 2011;60(Pt 9):1287-91 Wheeldon L, Worthington T, Lambert P Histidine acts as a co-germinant with glycine and taurocholate for Clostridium difficile spores. J Appl Microbiol. 2011. doi: 10.1111/j.1365-2672.2011.04953.x Karpanen TJ, Conway BR, Worthington T, Hilton AC, Elliott TS, Lambert PA. Enhanced chlorhexidine skin penetration with eucalyptus oil. . BMC Infect Dis. 2010;10: 278. Karpanen T, Hendry E, Worthington T, Lambert P, Conway B (2010). Chlorhexidine: Skin permeation and antisepsis. Industrial Pharmacy; 26: 12-15. Worthington T, Dunlop D, Casey A, Lambert P, Luscombe J, Elliott T (2010). Serum procalcitonin, interleukin-6, soluble intercellular adhesin molecule-1 and IgG to short chain exocellular lipoteichoic acid as predictors of infection in total prosthesis revision Br J Biomed Sci; 67 (2): 71-76 Green L, Worthington T, Hilton A, Lambert P (2009) Phenotypic characterisation of Clostridium difficile reveals lack of extracellular virulence factor production and significant differences in antibiogram profiles. Int J Antimicrob Agents doi:10.1016/j.ijantimicag.2009.10.018 Hendry E, Worthington T, Conway B; Lambert P (2009). Antimicrobial Efficacy of Eucalyptus Oil and 1,8-Cineole Alone and in Combination with Chlorhexidine Digluconate Against Microorganisms Grown in Planktonic and Biofilm Cultures. J Antimicrob Chemother;64(6):1219-25 Karpanen TJ, Worthington T, Conway BR, Hilton AC, Elliott TS, Lambert PA (2009). Permeation of chlorhexidine from alcoholic and aqueous solutions within excised human skin. Antimicrob Chemother; 53(4):1717-9. (online) Wheeldon L, Worthington T, Hilton AC, Lambert PA, Elliott TSJ. (2008). Sporicidal activity of two disinfectants against Clostridium difficile spores.Br J Nurs. 2008 Mar 13-26;17(5):316-20. (online)