Professor Ahmed’s laboratory was amongst the first laboratories to signal the importance of vascular growth factors in pregnancy and pioneered the concept of angiogenic imbalance theory in preeclampsia in the mid 1990s.

Wang K, Ahmad S, Cai M, Rennie J, Fujisawa T, Crispi F, Baily J, Miller MJ, Cudmore MJ, Hadoke PWF, Wang R, Gratacós E, Buhimschi IA, Buhimschi CS, and Ahmed A. (2013) Dysregulation of hydrogen sulfide (H2S) producing enzyme cystathionine ?-lyase (CSE) contributes to maternal hypertension and placental abnormalities in preeclampsia. Circulation (in press). Cudmore MJ, Hewett PW, Ahmad S, Wang KQ, Cai M, Al-Ani B, Fujisawa T, Sissaoui S, Ramma W, Miller M, Newby DE, Gu Y, Barleon B, Weich H and Ahmed A. (2012) Identification and functional characterisation of VEGF-A receptor heterodimerisation. Nat Comms3:972. doi: 10.1038/ncomms1977. Cudmore MJ, Ahmad S, Sissaoui S, Ramma W, Ma B, Fujisawa T, Al-Ani B, Wang K, Cai M, Crispi F, Hewett PW, Gratacós E, Egginton S and Ahmed A. (2012) Loss of Akt activity increases circulating soluble endoglin release in preeclampsia: identification of inter-dependency between Akt-1 and heme oxygenase-1. Eur Heart J 33:1150-8. Rosenberg VA, Buhimschi IA, Lockwood CJ, Paidas MJ, Dulay AT, Ramma W, Abdel-Razeq SS, Zhao G, Ahmad S, Ahmed A, Buhimschi CS. (2011). Heparin elevates circulating soluble Fms-Like Tyrosine immunoreactivity in pregnant women receiving anticoagulation therapy. Circulation 124(23):2543-53. Crispi F, Bijnens B, Figueras F, Bartrons J, Eixarch E, Le Noble F, Ahmed A, Gratacós E. (2010) Fetal growth restriction results in remodeled and less efficient hearts in children. Circulation 121(22):2427-36.