1978年出生，2006年毕业于中国科学院海洋研究所，获海洋生物学博士学位。先后参与了国家重点基础研究发展计划、国家高技术研究发展计划、国家自然科学基金重点项目、国家自然科学面上基金、农业部公益性行业项目等课题近10项。已发表SCI收录论文30余篇，其中第一作者（通讯作者）收录7篇。

专利 [1] 冯巍巍,张永春,王清,等. 一种低功耗水质生态模拟与控制系统. 2016-09-05. [2] 丛明,杨海萍,赵建民,等. 一种综合评价氨态氮对水生动物威胁的方法. 2015-08-21. [3] 李斐,曹璐璐,吴惠丰,等. 一种预测生物标志物p53与有机磷酸酯阻燃剂相互作用亲和力的方法. 2014-04-18. [4] 李斐,吴惠丰,曹璐璐,等. 预测海岸带持久性有机污染物消除速率的方法. 2014-01-07. [5] 赵建民,吴惠丰,王清,等. 一种紫贻贝g型溶菌酶基因及其重组蛋白和应用. 2011-12-15. [6] 王清,吴惠丰,赵建民,等. 紫贻贝g型溶菌酶基因及其重组蛋白和应用. 2011-12-15. [7] 吴惠丰,张林宝,赵建民,等. 菲律宾蛤仔防御素defensin B基因及其重组蛋白和应用. 2011-10-14. [8] 吴惠丰,张林宝,赵建民,等. 菲律宾蛤仔防御素defensin A基因及其重组蛋白和应用. 2011-10-14.

海洋环境毒理学

海洋环境毒理学。

[1] 高天赐,高学鲁,邢前国,等. 秋季牟平海洋牧场及其邻近海域沉积物-水界面营养盐交换通量[J]. 海洋环境科学,2020,39(03):387-392. [2] 刘辉,奉杰,赵建民. 海洋牧场生态系统监测评估研究进展与展望[J]. 科技促进发展,2020,16(02):213-218. [3] 王清,朱效鹏,赵建民. 滩涂生态牧场构建与展望[J]. 科技促进发展,2020,16(02):219-224. [4] Yang, B,Gao, XL,Zhao, JM,Lu, YX,&Gao, TC.(2020).Biogeochemistry of dissolved inorganic nutrients in an oligotrophic coastal mariculture region of the northern Shandong Peninsula, north Yellow Sea.MARINE POLLUTION BULLETIN,150,110693. [5] Zhu, Xiaopeng.,Ran, Wen.,Teng, Jia.,Zhang, Chen.,Zhang, Wenjing.,...&Wang, Qing.(2020).Microplastic Pollution in Nearshore Sediment from the Bohai Sea Coastline.BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY. [6] Yang, DL.,Han, YJ.,Chen, LZ.,Cao, RW.,Wang, Q.,...&Zhao, JM.(2019).A bactericidal permeability-increasing protein (BPI) from manila clam Ruditapes philippinarum: Investigation on the antibacterial activities and antibacterial action mode.FISH & SHELLFISH IMMUNOLOGY,93,841-850. [7] Lv, JS,Zhao, JM,Yang, DL,Wu, HF,&Cong, M.(2019).Tissue distribution and functional characterization of mytimacin-4 in Mytilus galloprovincialis.JOURNAL OF INVERTEBRATE PATHOLOGY,166,107215. [8] Yang, DL.,Han, YJ.,Chen, LZ.,Cao, RW.,Wang, Q.,...&Zhao, JM.(2019).A macin identified from Venerupis philippinarum: Investigation on antibacterial activities and action mode.FISH & SHELLFISH IMMUNOLOGY,92,897-904. [9] Zhang, HX.,Wang, Q.,Liu, SL.,Huo, D.,Zhao, JM.,...&Yang, HS.(2019).Genomic and Metagenomic Insights Into the Microbial Community in the Regenerating Intestine of the Sea Cucumber Apostichopus japonicus.FRONTIERS IN MICROBIOLOGY,10,1165. [10] Yang, DL.,Han, YJ.,Liu, YL.,Cao, RW.,Wang, Q.,...&Zhao, JM.(2019).A peptidoglycan recognition protein involved in immune recognition and immune defenses in Ruditapes philippinarum.FISH & SHELLFISH IMMUNOLOGY,88,441-448. [11] Hu, GG.,Han, YJ.,Yang, DL.,Cao, RW.,Wang, Q.,...&Zhao, JM.(2019).Molecular cloning and characterization of FADD from the manila clam Ruditapes philippinarum.FISH & SHELLFISH IMMUNOLOGY,88,556-566. [12] Yang, DL.,Han, YJ.,Chen, LZ.,Liu, YL.,Cao, RW.,...&Zhao, JM.(2019).Scavenger receptor class B type I (SR-BI) in Ruditapes philippinarum: A versatile receptor with multiple functions.FISH & SHELLFISH IMMUNOLOGY,88,328-334. [13] Cao, RW.,Zhang, TY.,Li, X.,Zhao, YT.,Wang, Q.,...&Zhao, JM.(2019).Seawater acidification increases copper toxicity: A multi-biomarker approach with a key marine invertebrate, the Pacific Oyster Crassostrea gigas.AQUATIC TOXICOLOGY,210,167-178. [14] Zhang, B.,Wu, D.,Yang, X.,Teng, J.,Liu, YL.,...&Wang, Q.(2019).Microplastic pollution in the surface sediments collected from Sishili Bay, North Yellow Sea, China.MARINE POLLUTION BULLETIN,141,9-15. [15] Lu, Z,Shan, XJ,Ji, CL,Zhao, JM,&Wu, HF.(2019).Proteomic responses induced by metal pollutions in oysters Crassostrea sikamea.JOURNAL OF OCEANOLOGY AND LIMNOLOGY,37(2),685-693. [16] Teng, J.,Wang, Q.,Ran, W.,Wu, D.,Liu, YF.,...&Zhao, JM.(2019).Microplastic in cultured oysters from different coastal areas of China.SCIENCE OF THE TOTAL ENVIRONMENT,653,1282-1292. [17] 魏帆,韩广轩,韩美,等. 1980~2017年环渤海海岸线和围填海时空演变及其影响机制[J]. 地理科学,2019,39(6):997-1007. [18] 李元超,吴钟解,梁计林,等. 近15年西沙群岛长棘海星暴发周期及暴发原因分析[J]. 科学通报,2019,64(33):3478-3484. [19] 张晨,王清,赵建民. 海洋微塑料输运的数值模拟研究进展[J]. 地球科学进展,2019,34(1):72-83. [20] Cao, Ruiwen.,Liu, Yongliang.,Wang, Qing.,Dong, Zhijun.,Yang, Dinglong.,...&Zhao, Jianmin.(2018).Seawater acidification aggravated cadmium toxicity in the oyster Crassostrea gigas: Metal bioaccumulation, subcellular distribution and multiple physiological responses.SCIENCE OF THE TOTAL ENVIRONMENT,642,809-823. [21] Chen, Lizhu.,Wu, Huifeng.,Zhao, Jianmin.,Zhang, Wei.,Zhang, Li.,...&Wang, Qing.(2018).The role of GST omega in metabolism and detoxification of arsenic in clam Ruditapes philippinarum.AQUATIC TOXICOLOGY,204,9-18. [22] 李晓炜,赵建民,刘辉,等. 渤黄海渔业资源三场一通道现状、问题及优化管理政策[J]. 海洋湖沼通报,2018(05):147-157. [23] 冉文,滕佳,刘永亮,等. 环渤海潮间带长牡蛎微塑料富集特征研究[J]. 海洋通报,2018,37(05):583-590. [24] Wei, Qianyu,Mu, Changkao,Wang, Chunlin,&Zhao, Jianmin.(2018).Molecular characterization, expression, and antibacterial activity of a c-type lysozyme isolated from the manila clam, Ruditapes philippinarum.FISH & SHELLFISH IMMUNOLOGY,81,502-508. [25] Cao, Ruiwen.,Liu, Yongliang.,Wang, Qing.,Zhang, Qianqian.,Yang, Dinglong.,...&Zhao, Jianmin.(2018).The impact of ocean acidification and cadmium on the immune responses of Pacific oyster, Crassostrea gigas.FISH & SHELLFISH IMMUNOLOGY,81,456-462. [26] Zhang, Yong,Gao, Xuelu,Guo, Weidong,Zhao, Jianmin,&Li, Yanfang.(2018).Origin and Dynamics of Dissolved Organic Matter in a Mariculture Area Suffering From Summertime Hypoxia and Acidification.FRONTIERS IN MARINE SCIENCE,5,UNSP 325. [27] Yang, Dinglong.,Zhang, Qianqian.,Wang, Qing.,Chen, Lizhu.,Liu, Yongliang.,...&Zhao, Jianmin.(2018).A defensin-like antimicrobial peptide from the manila clam Ruditapes philippinarum: Investigation of the antibacterial activities and mode of action.FISH & SHELLFISH IMMUNOLOGY,80,274-280. [28] Cao, Ruiwen.,Wang, Dan.,Wei, Qianyu.,Wang, Qing.,Yang, Dinglong.,...&Zhao, Jianmin.(2018).Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri.FRONTIERS IN PHYSIOLOGY,9,1173. [29] Cao, Ruiwen.,Liu, Yongliang.,Wang, Qing.,Yang, Dinglong.,Liu, Hui.,...&Zhao, Jianmin.(2018).Seawater Acidification Reduced the Resistance of Crassostrea gigas to Vibrio splendidus Challenge: An Energy Metabolism Perspective.FRONTIERS IN PHYSIOLOGY,9,880. [30] Wang, Dan.,Yang, Dinglong.,Wang, Qing.,Zhao, Ye.,Li, Chenghua.,...&Zhao, Jianmin.(2018).Two macrophage migration inhibitory factors (MIFs) from the clam Ruditapes philippinarum: Molecular characterization, localization and enzymatic activities.FISH & SHELLFISH IMMUNOLOGY,78,158-168. [31] Cao, Ruiwen.,Wang, Qing.,Yang, Dinglong.,Liu, Yongliang.,Ran, Wen.,...&Zhao, Jianmin.(2018).CO2-induced ocean acidification impairs the immune function of the Pacific oyster against Vibrio splendidus challenge: An integrated study from a cellular and proteomic perspective.SCIENCE OF THE TOTAL ENVIRONMENT,625,1574-1583. [32] 魏帆,韩广轩,张金萍,等. 1985—2015年围填海活动影响下的环渤海滨海湿地演变特征[J]. 生态学杂志,2018,37(05):1527-1537. [33] Cong, Ming.,Wu, Huifeng.,Cao, Tengfei.,Lv, Jiasen.,Wang, Qing.,...&Zhao, Jianmin.(2018).Digital gene expression analysis in the gills of Ruditapes philippinarum exposed to short- and long-term exposures of ammonia nitrogen.AQUATIC TOXICOLOGY,194,121-131. [34] 李斐,丁家旺,吴惠丰,等. 电化学方法研究石墨烯和磷酸三苯酯(TPP)与模拟生物膜间的相互作用[J]. 科学通报,2017,62(36):4285-4293. [35] Li, Fei.,Wang, Li.,Ji, Chenglong.,Wu, Huifeng.,Zhao, Jianmin.,...&Wu, Huifeng.(2017).Toxicological effects of tris(2-chloropropyl) phosphate in human hepatic cells.CHEMOSPHERE,187,88-96. [36] Xie, Jia.,Yang, Dinglong.,Sun, Xiyan.,Cao, Ruiwen.,Chen, Lizhu.,...&Zhao, Jianmin.(2017).Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas.BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,99(5),582-588. [37] Yu, Qian.,Yang, Dinglong.,Wang, Qing.,Zhang, Yingying.,Cong, Ming.,...&Zhao, Jianmin.(2017).Molecular characterization, expression and functional analysis of two Kazal-type serine protease inhibitors from Venerupis philippinarum.FISH & SHELLFISH IMMUNOLOGY,70,156-163. [38] Xie, J.,Yang, DL.,Sun, XY.,Cao, RW.,Chen, LZ.,...&Zhao, JM.(2017).Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas.BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,99(5),582-588. [39] 刘佳琳,徐兰兰,路珍,等. 基于核磁共振的褐牙鲆幼鱼组织代谢组学分析[J]. 海洋通报,2017,36(5):538-546. [40] Yang, Dinglong.,Wang, Qing.,Cao, Ruiwen.,Chen, Lizhu.,Liu, Yongliang.,...&Zhao, Jianmin.(2017).Molecular characterization, expression and antimicrobial activities of two c-type lysozymes from manila clam Venerupis philippinarum.DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,73,109-118. [41] 陈丽竹,王丹,曹瑞文,等. 菲律宾蛤仔对三价和五价无机砷的富集转化规律[J]. 海洋通报,2017,36(3):326-332. [42] 吴惠丰,张明兴,李斐,等. 石墨烯与抑癌基因p53 DNA片段相互作用的分子模拟与光谱学验证[J]. 生态毒理学报,2017,12(3):243-250. [43] Yang, Dinglong.,Wang, Qing.,Chen, Lizhu.,Liu, Yongliang.,Cao, Ruiwen.,...&Zhao, Jianmin.(2017).Molecular characterization and antibacterial activity of a phage-type lysozyme from the Manila clam, Ruditapes philippinarum.FISH & SHELLFISH IMMUNOLOGY,65,17-24. [44] 谢嘉,滕佳,刘永亮,等. Cd~(2+)和Pb~(2+)单一与复合污染对脊尾白虾的急性毒性效应研究[J]. 海洋科学,2017,41(5):27-33. [45] 曹滕飞,丛明,李兆艳,等. 氨态氮对菲律宾蛤仔毒理机制研究的内参基因筛选[J]. 生态毒理学报,2017,12(2):182-190. [46] Cong, Ming,Wu, Huifeng,Yang, Haiping,Zhao, Jianmin,Lv, Jiasen,&Wu, HF.(2017).Gill damage and neurotoxicity of ammonia nitrogen on the clam Ruditapes philippinarum.ECOTOXICOLOGY,26(3),459-469. [47] Wu, Huifeng.,Liu, Jialin.,Lu, Zhen.,Xu, Lanlan.,Ji, Chenglong.,...&Wu, HF .(2017).Metabolite and gene expression responses in juvenile flounder Paralichthys olivaceus exposed to reduced salinities.FISH & SHELLFISH IMMUNOLOGY,63,417-423. [48] Xu, Lanlan,Ji, Chenglong,Zhao, Jianmin,Wu, Huifeng,&Wu, HF .(2016).Metabolic responses to metal pollution in shrimp Crangon affinis from the sites along the Laizhou Bay in the Bohai Sea.MARINE POLLUTION BULLETIN,113(1-2),536-541. [49] Xie, Jia.,Zhao, Yun.,Wang, Qing.,Wu, Huifeng.,Teng, Jia.,...&Zhao, JM .(2016).An integrative biomarker approach to assess the environmental stress in the north coast of Shandong Peninsula using native oysters, Crassostrea gigas (vol 112, pg 318, 2016).MARINE POLLUTION BULLETIN,113(1-2),600-600. [50] Cong, M,Zhao, JM,Lu, JS,Ren, ZM,Wu, HF,&Wu, HF .(2016).Homologous cloning, characterization and expression of a new halophyte phytochelatin synthase gene in Suaeda salsa.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,34(5),1034-1043. [51] Ji, CL.,Yu, DL.,Wang, Q.,Li, F.,Zhao, JM.,...&Wu, HF .(2016).Impact of metal pollution on shrimp Crangon affinis by NMR-based metabolomics.MARINE POLLUTION BULLETIN,106(1-2),372-376. [52] Yu, DL,Ji, CL,Zhao, JM,Wu, HF,&Wu, HF .(2016).Proteomic and metabolomic analysis on the toxicological effects of As (III) and As (V) in juvenile mussel Mytilus galloprovincialis.CHEMOSPHERE,150,194-201. [53] Ji, CL.,Li, F.,Wang, Q.,Zhao, JM.,Sun, ZD.,...&Wu, HF .(2016).An integrated proteomic and metabolomic study on the gender-specific responses of mussels Mytilus galloprovincialis to tetrabromobisphenol A (TBBPA).CHEMOSPHERE,144,527-539. [54] Wang, Q.,Cao, RW.,Ning, XX.,You, LP.,Mu, CK.,...&Zhao, JM .(2016).Effects of ocean acidification on immune responses of the Pacific oyster Crassostrea gigas.FISH & SHELLFISH IMMUNOLOGY,49,24-33. [55] 于倩,王清,韩伟,等. 具槽帕拉藻代谢组提取方法的比较研究[J]. 海洋通报,2015,34(6):703-709. [56] 于倩,王清,袁泽轶,等. 不同形态磷源对具槽帕拉藻(Paralia sulcata)生长和磷酸酶活性的影响[J]. 海洋与湖沼,2015,46(5):1018-1023. [57] 吴惠丰,曹璐璐,李斐,等. 典型持久性有机污染物与抑癌基因相互作用的分子模拟与验证[J]. 科学通报,2015,60(19):1804-1809. [58] Wu, Huifeng,Cao, Lulu,Li, Fei,Lian, Peiwen,Zhao, Jianmin,&Li, F .(2015).Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells.CHEMOSPHERE,126,32-39. [59] Li Fei,Wu Huifeng,Wang Qing,Li Xuehua,Zhao Jianmin,&Wu, HF .(2015).Glutathione S-transferase (GST) gene expression profiles in two marine bivalves exposed to BDE-47 and their potential molecular mechanisms.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,33(3),705-713. [60] Wei, Lei.,Wang, Qing.,Ning, Xuanxuan.,Mu, Changkao.,Wang, Chunlin.,...&jmzhao@yic.ac.cn.(2015).Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO(2).COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS,13,16-23. [61] Wu, Luning.,Zhang, Lei.,Zhao, Jianmin.,Ning, Xuanxuan.,Mu, Changkao.,...&wangchunlin@nbu.edu.cn.(2015).Cloning and expression of a transcription factor activator protein-1 (AP-1) member identified from manila clam Venerupis philippinarum.GENE,557(1),106-111. [62] Ji, Chenglong,Wu, Huifeng,Wei, Lei,Zhao, Jianmin,&Wu, HF .(2014).iTRAQ-based quantitative proteomic analyses on the gender-specific responses in mussel Mytilus galloprovincialis to tetrabromobisphenol A.AQUATIC TOXICOLOGY,157,30-40. [63] Li, Fei.,Yang, Xianhai.,Li, Xuehua.,Li, Renmin.,Zhao, Jianmin.,...&hfwu@yic.ac.cn.(2014).Determination and Prediction of the Binding Interaction between Organophosphate Flame Retardants and p53.CHEMICAL RESEARCH IN TOXICOLOGY,27(11),1918-1925. [64] Li, Fei.,Li, Renmin.,Yang, Xianhai.,You, Liping.,Zhao, Jianmin.,...&hfwu@yic.ac.cn.(2014).The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach.MARINE POLLUTION BULLETIN,85(2),516-521. [65] Liu, Xiaoli.,Ji, Chenglong.,Zhao, Jianmin.,Wang, Qing.,Li, Fei.,...&Liu, XL .(2014).Metabolic profiling of the tissue-specific responses in mussel Mytilus galloprovincialis towards Vibrio harveyi challenge.FISH & SHELLFISH IMMUNOLOGY,39(2),372-377. [66] Ji, Chenglong,Zhao, Jianmin,Wu, Huifeng,&Wu, HF .(2014).Gender-specific metabolic responses in gonad of mussel Mytilus galloprovincialis to 2,2 ',4,4 '-tetrabromodiphenyl ether.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,37(3),1116-1122. [67] Zhang, Yingying.,Wang, Qing.,Ji, Yinglu.,Zhang, Qian.,Wu, Huifeng.,...&jmzhao@yic.ac.cn.(2014).Identification and mRNA expression of two 17 beta-hydroxysteroid dehydrogenase genes in the marine mussel Mytilus galloprovincialis following exposure to endocrine disrupting chemicals.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,37(3),1243-1255. 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[72] Wu, Huifeng,Ji, Chenglong,Wei, Lei,Zhao, Jianmin,&Lu, Hongjian.(2013).Proteomic and metabolomic responses in hepatopancreas of Mytilus galloprovincialis challenged by Micrococcus luteus and Vibrio anguillarum.JOURNAL OF PROTEOMICS,94,54-67. [73] Liu, Xiaoli,Ji, Chenglong,Zhao, Jianmin,&Wu, Huifeng.(2013).Differential metabolic responses of clam Ruditapes philippinarum to Vibrio anguillarum and Vibrio splendidus challenges.FISH & SHELLFISH IMMUNOLOGY,35(6),2001-2007. [74] Liu, Xiaoli,Zhao, Jianmin,Wu, Huifeng,&Wang, Qing.(2013).Metabolomic analysis revealed the differential responses in two pedigrees of clam Ruditapes philippinarum towards Vibrio harveyi challenge.FISH & SHELLFISH IMMUNOLOGY,35(6),1969-1975. [75] Wu, Huifeng,Ji, Chenglong,Wei, Lei,&Zhao, Jianmin.(2013).Evaluation of protein extraction protocols for 2DE in marine ecotoxicoproteomics.PROTEOMICS,13(21),3205-3210. [76] Ji, Chenglong,Wu, Huifeng,Wei, Lei,Zhao, Jianmin,Lu, Hongjian,&Yu, Junbao.(2013).Proteomic and metabolomic analysis of earthworm Eisenia fetida exposed to different concentrations of 2,2 ',4,4 '-tetrabromodiphenyl ether.JOURNAL OF PROTEOMICS,91,405-416. [77] Ji, Chenglong,Wu, Huifeng,Wei, Lei,Zhao, Jianmin,&Yu, Junbao.(2013).Proteomic and metabolomic analysis reveal gender-specific responses of mussel Mytilus galloprovincialis to 2,2 ',4,4 '-tetrabromodiphenyl ether (BDE 47).AQUATIC TOXICOLOGY,140,449-457. [78] Cong Ming,Lu Jiasen,Wu Huifeng,&Zhao Jianmin.(2013).Effect of cadmium on the defense response of Pacific oyster Crassostrea gigas to Listonella anguillarum challenge.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,31(5),1002-1009. [79] Ji, Chenglong,Wu, Huifeng,Wei, Lei,Zhao, Jianmin,Wang, Qing,&Lu, Hongjian.(2013).Responses of Mytilus galloprovincialis to bacterial challenges by metabolomics and proteomics.FISH & SHELLFISH IMMUNOLOGY,35(2),489-498. 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