王晶
副研究员 硕导
个人简介
博士，1988年生，副研究员，中国科学院青年创新促进会会员，硕士生导师。2010年毕业于安徽师范大学，获学士学位;2015年在中国科学院水生生物研究所获博士学位。2015年进入中国科学院水生生物研究所工作，历任助理研究员(2015)、副研究员(2019)
研究领域
1)鱼类低氧耐受与适应的遗传基础;2)低氧信号转导的分子机制;3)低氧信号转导与天然免疫反应
近期论文
1、Jing Wang, Dawei Zhang, Juan Du, Chi Zhou, Zhi Li, Xing Liu, Gang Ouyang and Wuhan Xiao. Tet1 facilitates hypoxia tolerance by stabilizing the HIF-_ proteins independent of its methylcytosine dioxygenase activity. Nucleic Acids Research. 2017,45(22): 12700-12714.
2、Jing Wang, Xiaoqian Leng , Guiping Wang , Xiaoyang Wan & Hong Cao. The construction of intrahepatic cholangiocarcinoma model in zebrafish. Scientific reports, 2017,7.1341.
3、Jing Wang, Wei Zhang, Wei Ji, Xing Liu, Gang Ouyang, Wuhan Xiao*. The Von Hippel-Lindau protein suppresses androgen receptor activity. Molecular Endocrinology, 2014, 28(2): 239-248
4、Wei Ji, Jing Wang, Wei Zhang, Xing Liu, Gang Ouyang, Wuhan Xiao*. pVHL acts as a downstream target of E2F1 to suppress E2F1 activity. Biochemical Journal, 2014, 457: 185-195.
5、Dawei Zhang, Jing Wang, Chi Zhou, Wuhan Xiao*. Zebrafish akt2 is essential for survival, growth, bone development, and glucose homeostasis. Mechanisms of Development. 2017, 143:42-52.
6、Xiaolian Cai, Dawei Zhang, Jing Wang , Xing Liu , Gang Ouyang , Wuhan Xiao. Deletion of the fih gene encoding an inhibitor of hypoxia-inducible factors increases hypoxia tolerance in zebrafish. Journal of Biological Chemistry, 2018, 293: 15370.
7、Yu Chen, Chi Zhou, Wei Ji , Zhichao Mei, Bo Hu, Wei Zhang, Dawei Zhang, Jing Wang, Xing Liu, Gang Ouyang, Jiangang Zhou, Wuhan Xiao*. ELL targets ELL targets c-Myc for proteasomal degradation and suppresses tumour growth. Nature Communications, 2016, 7: 11057 .