研究领域
药物设计、合成与构效关系研究；精细化工产品绿色合成工艺及工业化研究
近期论文
1. Synthesis and biological evaluation of 3-([1,2,4]triazolo[4,3-a]pyridin-3-yl)-4-(indol-3-yl)-maleimides as potent, selective GSK-3 beta inhibitors and neuroprotective agent. Bioorg. med. chem. 2015,47(22):3473-3478.
2.Synthesis and Evaluationof3-(furo[2,3-b]pyridin-3-yl)-4-(1H-indol-3-yl)-maleimides as Novel GSK-3 InhibitorsandAnti-Ischemic Agents. chem boil drg des.2015,23(5),1179-1188
3.Two-Step Synthesis of Some Novel Monoindolylmaleimides. Asian J.Chem.2014,26(14),4399-4404
4.Synthesis and Biological Evaluation of 3-Benzisoxazolyl-4-indolylmaleimides as Potent, Selective Inhibitors of Glycogen Synthase Kinase-3 beta. molecules 2013,18(5),5498-5516
5.Design, Synthesis, and Evaluation of 3-Aryl-4-pyrrolyl-maleimides as Glycogen Synthase Kinase-3 beta Inhibitors. archive der pharmazie 2013,346(5),349-358
6.Design, synthesis and evaluation of 7-azaindazolyl -indolyl-maleimides as glycogen synthase kinase-3β（GSK-3β）inhibitors ,Eur. J.Med.Chem 2013,68,361-371