研究领域
过渡金属催化绿色有机合成；药物及精细化学品开发
近期论文
1. Wu, D.; Zhang, J.; Cui, J.; Zhang, W.; Liu, Y.* AgNO2-mediated direct nitration of quinoxaline tertiary benzylic C-H bond and direct conversion of 2-methyl quinoxalines into related nitriles. Chem. Commun., 2014, 50, 10857-10860.
2. Zhang, W.; Zhang, J.; Ren, S.; Liu, Y.* Palladium-Catalyzed Aromatic C-H Bond Nitration Using Removable Directing Groups: Regiospecific Synthesis of Substituted o-Nitrophenols from Related Phenols. J. Org. Chem., 2014, 79(23), 11508-11516.
3. Zhang, J.; Wu, D.; Chen, X.; Liu, Y.*; Xu, Z. Copper-Catalyzed Oxidative Cyclization of 1,5-Enynes with Concomitant C−C Bond Cleavage: An Unexpected Access to 3-Formyl-1-indenone Derivatives. J. Org. Chem., 2014, 79(11), 4799-4808.
4. Zhang, W.; Wu, D.; Zhang, J.; Liu, Y.* Regiospecific Synthesis of Substituted 2-Nitrobenzaldehydes from Benzaldehydes through Palladium-Catalyzed Chelation-Assisted C–H Nitration. Eur. J. Org. Chem., 2014, 5827-5835.
5. Wu, D.; Zhang, J.; Wang, H.; Zhang, J.; Liu, Y.*; Liu, M. Activation of Dioxygen in Air by Phenol/Selectfluor System: An Application in the Oxidation-Dimerization of Alkynes to 2-ene-1,4-diones. Asia. J. Org. Chem., 2014, 3, 1163-1167.
6. Zhang, W.; Zhang, J.; Liu, Y.*; Xu, Z. Combination of Cu(0) Powder and Selectfluor Enables Generation of Cationic Copper Species for Mild 1,2-Dicarbonylation of Alkynes. Synlett, 2013, 24, 2709-2714.
7. Liu, Y.*; Chen, X.; Zhang, J.; Xu, Z. Gold(I)-Catalyzed Oxidative Diketonization of Alkynes and Its Application for the One-Pot Synthesis of Quinoxaline Derivatives. Synlett, 2013, 11, 1371-1376.
8. Liu Y. K.*; Jian B.; Zhang W.; Xu Z. Y. Multifold Bond Cleavage and Formation between MeOH and Quinoxalines (or Benzothiazoles): Synthesis of Carbaldehyde. J. Org. Chem. 2013, 78, 966-980.
9. Zhang W.; Lou S. J.; Liu Y. K.*; Xu Z. Y. Palladium-Catalyzed Chelation-Assisted Aromatic C-H Nitration: Regiospecific Synthesis of Nitroarenes Free from the Effect of the Orientation Rules. J. Org. Chem. 2013, 78, 5932-5948.
10. Liu Y. K.*; Chen. X. L..; Zhang J.; Xu Z. Y. Gold(I)-Catalyzed Oxidative Diketonization of Alkynes and Its Application for the One-Pot Synthesis of Quinoxaline Derivatives. Synlett, 2013, 24, 1371-1376.
11. Lou S. J.; Xu D. Q.; Xia A. B.; Wang Y. F.; Liu Y. K.; Du X. H.; Xu Z. Y. Pd(OAc)2-catalyzed regioselective aromatic C–H bond fluorination. Chem. Commun. 2013, 49, 6218-6220.
12. Liu Y. K.*; Zhu J.; Qian J. Q.; Xu Z. Y. Gold-Catalyzed Simultaneous Formation of C-C, C=O, and C-F bonds in the Presence of Selectfluor: A Synthesis of Fluoroindenes from Allene Esters. J. Org. Chem., 2012, 77, 5411-5417.
13. Qian J. Q.; Liu Y. K.*；Cui J. H., Xu Z. Y. Gold(I)-Catalyzed Synthesis of 1,5-Benzodiazepines Directly from o-Phenylenediamines and Alkynes. J. Org. Chem., 2012, 77, 4484-4490.
14. Liu, Y. K.*; Zhu, J.; Qian, J. Q.; Jiang, B.; Xu, Z. Y. Gold(III)-Catalyzed Tandem Conjugate Addition/Annulation of 4-hydroxycoumarins with a,b-Unsaturated Ketones. J. Org. Chem., 2011, 76, 9096-9101.
15. Qian, J. Q.; Liu, Y. K.*; Zhu, J.; Jiang, B.; Xu, Z. Y.* A Novel Synthesis of Fluorinated Pyrazoles via Gold(I)-Catalyzed Tandem Aminofluorination of Alkynes in the Presence of Selectfluor. Org. Lett., 2011, 13, 4220-4223.
16. Liu, Y. K.*; Lou, S. J.; Xu, D. Q.; Xu, Z. Y. Regiospecific Synthesis of Nitroarenes via Palladium-Catalyzed Nitrogen Donor-Directed Aromatic C-H Nitration. Chem. Eur. J., 2010, 16, 13590-13593.
17. Liu, Y. K.*; Qian, J. Q.; Lou, S. J.; Xu, Z. Y. Gold(III)-Catalyzed Tandem Reaction of O-Arylhydroxylamines with 1,3-Dicarbonyl Compounds: Efficient and Highly Selective Synthesis 3-Carbonylated Benzofuran Derivatives. J. Org. Chem., 2010, 75(18), 6300-6303.
18. Liu, Y. K.*; Qian, J. Q.; Lou, S. J.; Zhu, J.; Xu, Z. Y. Gold(III)-Catalyzed Tandem Reaction of Ketones with Phenols: Efficient and Highly Selective Synthesis of Functionalized 4H-Chromenes. J. Org. Chem., 2010, 75(4), 1309-1312.