刘建新，浙江大学求是特聘教授，博士生导师，畜牧学科负责人；兼任中国畜牧兽医学会理事，国家饲料产业联盟副理事长，中国奶业协会专家委员会常务委员、饲养饲料与环境专业委员会副主任等。1982年毕业于浙江农业大学畜牧兽医系，1982年受国家公派赴日本北海道大学农学部攻读研究生学位，1985年获得硕士学位，1988年获博士学位；当年回国任教，1991年晋升副教授，1994年底晋升教授。1995~1996年，英国Rowett研究所从事博士后；1999~2000年，作为洪堡研究学者在德国基尔大学动物营养生理与代谢研究所从事合作研究。1993~1998年，任浙江农业大学动物科学学院副院长、院长；2001~2013年，历任浙江大学动物科学学院副院长、常务副院长、院长等；2014~2020年，任浙江大学农业生命环境学部副主任。1998~2008年任浙江省畜牧兽医学会理事长；2000~2008年任中国畜牧兽医学会动物营养学分会副理事长，2008~2012年任中国畜牧兽医学会动物营养学分会理事长。 主要从事奶牛营养、泌乳生理、瘤胃微生物与发酵调控、饲料资源开发与利用等教学及科研工作；承担国家973计划课题、国家杰出青年基金、国家自然基金、国家支撑计划课题、国际合作重点项目等30多项国家、省部级科研项目。1999年获得德国著名的洪堡基金，2002年入选教育部“跨世纪优秀人才培养计划”，2003年获得国家杰出青年基金，曾获国际科学基金会Silver Jubilee Award。在Microbiome、Journal of Dairy Science、Journal of Animal Science & Biotechnology、Animal Microbiome等刊物发表系列研究成果，出版科技专著6部；科研成果荣获国家和省部级科技进步奖6项，2009年被评为浙江省教学名师，2018年被评为浙江省优秀教师，2022年荣获浙江大学永平教学贡献奖。现担任Journal of Animal Physiology and Animal Nutrition、Animal Bioscience、Journal of Animal Science and Biotechnology、Animal Nurition、《动物营养学报》、《中国畜牧杂志》等刊物编委，具有较高的国内知名度，在国际同行中也有一定影响。曾赴日本、英国、德国学习与合作科研，与美国、加拿大、日本、澳大利亚、德国、韩国等众多国家的学者有密切合作与联系。 论著 刘建新，章亭洲，王谦主编. 2024. 生物饲料制造技术的理论与实践. 浙江科技出版社, 杭州 刘建新主编. 2019. 反刍动物营养生理. 农业出版社, 北京 刘建新主编, 2012. 动物营养研究进展-2012. 中国农业科技出版社, 北京 刘建新(副主编). 2011. 饲料添加剂学. 农业出版社, 北京. 刘建新主编. 2004. 浙江效益农业百科全书-奶牛. 中国农业科技出版社, 北京. 刘建新(参编). 2004. 反刍动物营养学(冯仰廉主编). 中国科学出版社, 北京. 陈代文, 冯定远, 刘建新. 2003. 饲料添加剂学. 农业出版社, 北京. 刘建新(参编). 2003. 配合饲料学(冯定远主编). 上海科学技术出版社. 刘建新(参编). 2003. 饲料添加剂安全使用规范(蔡辉益、杨振海主编). 中国农业出版社, 北京. 刘建新, 吴跃明, 叶均安, 周卫东, 陈维虎. 2002. 干草秸秆青贮饲料加工技术. 中国农业科技出版社, 北京 刘建新(参译). 2002. 奶牛饲养标准, NRC(第10版)( 孟庆翔主译). 中国农业大学出版社, 北京 刘建新, 王恬, 张宏福. 2002. 饲料营养研究进展 - 2002. 畜牧与兽医杂志社, 南京. 刘建新(参编). 2002. 秸秆养畜–中国的经验(郭庭双等编著). 粮农组织家畜生产及卫生文集- 149. FAO, 罗马. 孟庆翔, 王康宁, 刘建新, 单安山. 2002. 饲料学, 中国农业大学出版社, 北京. 戴旭明, 刘建新, 吕建涛. 1999. 山羊养殖与经营指南. 浙江省科技出版社, 杭州. 刘建新, 张宏福, 王康宁. 1998. 饲料营养研究进展 - 1998. 亚洲中医药杂志社, 澳门. 刘建新(参编). 1996. 秸秆畜牧业(郭庭双主编). 上海科学技术出版社.

反刍动物营养、乳品质形成机理及其调控、饲料资源开发利用

兼任中国畜牧兽医学会理事、中国奶业协会饲养饲料与环境专业委员会副主任、全国饲料与饲料添加剂评审委员会委员、动物营养国家重点实验室学委会委员等。

2024 1. Zang XW, Sun HZ, Xue MY, Liang SL, Guan LL, Liu JX. 2024. Genotype-associated heritable rumen bacteria can be a stable microbiota passed to the offspring. ISME Commun. 4(1):ycad20 https://doi.org/10.1093/ismeco/ycad020 2. Xue MY, Xie YY, Zang XW, Zhong YF, Ma XJ, Sun HZ, Liu JX. 2024. Deciphering functional groups of rumen microbiome and their underlying causal relationships in shaping host traits. iMeta, 3:e225 https://doi.org/10.1002/imt2.225 3. Zeng J, Wang DM, Sun HZ, Liu HY, Zhao FQ, Liu JX. 2024. Heat stress affects mammary metabolism by influencing the plasma flow to the glands. J Anim Sci Biotechnol. 15(1): 92 https://doi.org/10.1186/s40104-024-01050-3 4. Tang YF, Liu XH, Zhu SL, Jia MH, Liu JX, Sun HZ. 2024. New insights into the enteric methane production based on the archaeal genome atlas of ruminant gastrointestinal tract. J Adv Res. 18:S2090-1232(24)00418-1. https://doi.org/10.1016/j.jare.2024.09.016 5. Yan YN, Zhu SL, Jia MH, Chen HY, Qi WLL, Gu FF, Valencak TG, Liu JX, Sun HZ. 2024. Advances in single-cell transcriptomics in animal research. J Anim Sci Biotechnol. 15(1):102. https://doi.org/10.1186/s40104-024-01063-y 6. Jia MH, Zhu SL, Xue MY, Chen HY, Xu JH, Song MD, Tang YF, Liu XH, Tao Ye, Zhang HY, Liu JX, Wang YC, Sun HZ. 2024. Single-cell transcriptomics across 2,534 microbial species reveals functional heterogeneity in the rumen microbiome. Nature Microbiol. 9:1884. https://doi.org/10.1038/s41564-024-01723-9 7. Zhu SL, Gu FF, Tang YF, Liu XH, Jia MH, Valencak TG, Liu JX, Sun HZ. 2024. Dynamic fecal microenvironment properties enable predictions and understanding of peripartum blood oxidative status and nonesterified fatty acids in dairy cows. J Dairy Sci. 107(1):573-592 https://doi.org/10.3168/jds.2022-23066 8. Jin HY, Liu JX, Wang DM. 2024. Antioxidant potential of exosomes in animal nutrition. Antioxidants. 13(8):964. https://doi.org/10.3390/antiox13080964 9. Hu ZZ, Lu Yi, Cai Jie, Liu JX, Wang DM. 2024. Cross-oxygen gradients transcriptomic comparison revealed the central role of MAPK and Hippo in hypoxia mediated mammary proliferation inhibition. Antioxidants. 13:288. https://doi.org/10.3390/antiox13030288 10. Hu ZZ, Luo L, Lu Y, Cai J, Liu JX, Wang DM. 2024. Role of hypoxia in regulating mammary apoptosis-mediated lactation persistency alteration in high-yielding dairy cows. Anim Nutriomics. 1(1):e3, 1-11 https://doi.org/10.1017/anr.2024.5 11. Jia Lei, Zhang WY, Luo Tao, Li YT, Shu JH, Strand Julie, Yue Yuan, Purup Stig, Liu JX, Shi HB. 2024. Establishment of goat mammary organoid cultures modeling the mammary gland development and lactation. J Anim Sci Biotechnol. 15(1):124 https://10.1186/s40104-024-01084-7 2023 12. Zeng J, Cai J, Wang DM, Liu HY, Liu JX. 2023. Heat stress affects dairy cow health status through blood oxygen availability. J Anim Sci Biotechnol. 14:112. https://doi.org/10.1186/s40104-023-00915-3 13. Zhang Xu, Wang DM, Liu JX. 2023. Hypoxia-inducible factor-1α is involved in response to heat stress in lactating dairy cows. J Therm Biol. 112: 103460. https://doi.org/10.1016/j.jtherbio.2023.103460 14. Du YF, Gao YA, Hu MY, Hou JX, Yang LH, Wang XH, Du WJ, Liu JX, Xu QB. Colonization and development of the gut microbiome in calves. J Anim Sci Biotechnol. 14:46 https://doi.org/10.1186/s40104-023-00856-x 15. Liu HY, Wei XS, Dai WT, Xu LB, Wang C, Liu JX. The functional and regulatory entities underlying free and peptide-bound amino acid transporters in the bovine mammary gland. JDS Commun. 4(3):235=239. https://doi.org/10.3168/jdsc.2022-0292 16. Cai J, Peng Jie, Feng J, Li RC, Ren P, Zhang XW, Wu ZZ, Lu Yi, Luo L, Hu ZZ, Wang JY, Dai XM, Zhao P, Wang J, Liu JX, Deng RR, Wang DM. 2023. Antioxidant hepatic lipid metabolism can be promoted by orally administered inorganic nanoparticles. Nat Commun. 14(1):3643. https://doi.org/10.1038/s41467-023-39423-3 17. Cai J, Liang SL, Xie YY, Zang XW, Jiang LY, Miao Chao, Liu JX, Wang DM. 2023 Milk yield variation partially attributed to blood oxygen-mediated neutrophil activation in lactating dairy goats. Br J Nutr. 129(3):369-380 https://doi.org/10.1017/S0007114522001015 18. Wu JJ, Zhu S, Tang YF, Gu F, Valencak TG, Liu JX, Sun HZ. 2023. Age- and microbiota-dependent cell stemness plasticity revealed by cattle cell landscape. Research. 6: Article 0025. https://doi.org/10.34133/research.0025 19. Gu FF, Zhu SL, Hou JX, Tang YF, Liu JX, Xu QB, Sun HZ. 2023. The hindgut microbiome contributes to host oxidative stress in postpartum dairy cows by affecting glutathione synthesis process. Microbiome. 11:87 https://doi.org/10.1186/s40168-023-01535-9 20. Gu FF, Zhu SL, Tang YF, Liu XH, Jia MH, Malmuthuge N, Valencak TC, McFadden JW, Liu JX, Sun HZ. 2023. Gut microbiome is linked to functions of peripheral immune cells in transition cows during excessive lipolysis. Microbiome. 11(1):40 https://doi.org/10.1186/s40168-023-01492-3 21. Mao JD, Zhang Y, Liu JX, Wang HF. 2023. Gut microbiota and growth performance of offspring are influenced by wet nurse in pigs using cross-fostering trial. J Sci Food Agric. 103(2): 865-876 https://doi.org/10.1002/jsfa.12198 2022 22. Jiang LY, Sun HZ, Gu FF, Jin He, Zhao FQ, Liu JX. 2022. Blood neutrophil extracellular traps: A new target for detection of the mammary health for transition dairy cows. J Anim Sci Biotechnol. 13:131. https://doi.org/10.1186/s40104-022-00782-4 23. Zang XW, Sun HZ, Xue MY, Zhang Z, Plastow G, Yang TF, Guan LL, Liu JX. 2022. Heritable and non-heritable rumen bacteria are associated with different characters of lactation performance of dairy cows. mSystems. 7(5):e0042222 https://doi.org/10.1128/msystems.00422-22 24. Gu FF, Jiang LY, Wang DM, Zhao FQ, Liu JX. 2022. Supplementation with N-carbamoylglutamate during the transition period improves the functions of neutrophils and reduces the inflammation and oxidative stress in dairy cows. J Dairy Sci. 105(7):5786-5795 https://doi.org/10.3168/jds.2021-21159 25. Wang B, Sun HZ, Wang DM, Liu HY, Liu JX. 2022. Constraints on the utilization of cereal straw as a roughage source in lactating dairy cows: A review from the perspective of systems biology. Anim Nutr. 9:240-248 https://doi.org/10.1016/j.aninu.2022.01.002 26. Jiang LY, Sun HZ, Guan RW, Shi FS, Zhao FQ, Liu JX. 2022. Formation of blood neutrophil extracellular traps enhance the mastitis risk of dairy cows during the perinatal period. Front Immunol. 13:880578 https://doi.org/10.3389/fimmu.2022.880578 27. Xie YY, Sun HZ, Xue MY, Liu JX. 2022. Metagenomics reveals differences in microbial composition and metabolic functions in the rumen of dairy cows with different residual feed intake. Anim Microbiome. 4:19 https://doi.org/10.1186/s42523-022-00170-3 28. Xue MY, Xie YY, Zhong YF, Ma XJ, Sun HZ, Liu JX. 2022. Integrated meta-omics reveal new ruminal microbial features associated with feed efficiency in dairy cows. Microbiome, 10:32 https://doi.org/10.1186/s40168-022-01228-9 29. Wu, JJ, Zhu SL, Tang YF, Gu FF, Liu JX, Sun HZ. 2022. Microbiota-host crosstalk in the newborn and adult rumen at single-cell resolution. BMC Biol. 20:280 https://doi.org/10.1186/s12915-022-01490-1 30. Liu XH, Tang YF, Wu JJ, Liu JX, Sun HZ. 2022. Invited Review: Feedomics provide interactive strategies between genes and nutrition for improved production in cattle. Anim Nutr. 9:314-319 https://doi.org/10.1016/j.aninu.2022.03.002 31. Wu JJ, Zhu SL, Gu FF, Valencak TG, Liu JX, Sun HZ. 2022. Cross-tissue single-cell transcriptomic landscape reveals the key cell subtypes and their potential roles in the nutrient absorption and metabolism in dairy cattle. J Adv Res. 37:1-18 https://doi.org/10.1016/j.jare.2021.11.009 32. Xue MY, Wu JJ, Xie YY, Zhu SL, Zhong YF, Liu JX, Sun HZ. 2022. Investigation of fiber utilization in the rumen of dairy cows based on metagenome-assembled genomes and single-cell RNA sequencing. Microbiome. 10:11 https://doi.org/10.1186/s40168-021-01211-w 33. Li LP, Peng KL, Xue MY, Zhu SL, Liu JX, Sun HZ. 2022. An age effect of rumen microbiome in dairy buffaloes revealed by metagenomics. Microorganisms. 10: 1491. https://doi.org/10.3390/microorganisms10081491 34. Ren P, Deng MM, Feng J, Li RC, Ma XJ, Liu JX. Wang DM. 2022. Partial replacement of oat hay with whole-plant hydroponic barley seedlings modulates ruminal microbiota and affects growth performance of Holstein heifers. Microorganisms. 10(10):2000. https://doi.org/110.3390/microorganisms10102000 35. Cai Jie, Peng Jie, Zang XW, Feng Juan, Zheng BZ, Wang JY, Wang Juan, Yan M, Liu JX, Deng RR, Wang DM. 2022. Mammary leukocyte-assisted nanoparticle transport enhances targeted milk trace mineral delivery. Adv Sci 9:2200841. https://doi.org/10.1002/advs.202200841 36. Feng Juan, Peng WC, Hu ZZ, Cai Jie, Liu JX, Wang DM. 2022. Multiple-vessel-based blood gas profiles analysis revealed the potential of blood oxygen in mammary vein as indicator of mammary gland health risk of high-yielding dairy cows. Animals.12:1484. https://doi.org/10.3390/ani12121484 37. Wang CH, Zhao FQ, Liu JX, Liu HY. 2022. The ubiquitin ligase Nedd4-2 mediates the regulation of PepT2 by mTORC1 in bovine mammary epithelial cells. Anim Nutr. 10:12-18. https://doi.org/10.1016/j.aninu.2021.11.008 38. Dai WT, White Robin, Liu JX, Liu HY. 2022. Organelles coordinate milk production and secretion during lactation: Insights into mammary pathologies. Prog Lipid Res. 86:101159. https://doi.org/10.1016/j.plipres.2022.101159 39. Hou PF, Dai WT, Jin YS, Zhao FQ, Liu JX, Liu HY. 2022. Maternal exposure to di-2-ethylhexyl phthalate (DEHP) depresses lactation capacity in mice. Sci Total Environ. 837:155813. http://dx.doi.org/10.1016/j.scitotenv.2022.155813 40. Zhang WY, Zhang CH, Luo Jun, Xu HF, Liu JX, Loor Juan J, Shi HB. 2022. The LXRB-SREBP1 network regulates lipogenic homeostasis by controlling the synthesis of polyunsaturated fatty acids in goat mammary epithelial cells. J Anim Sci Biotechnol. 13:120 https://doi.org/10.1186/s40104-022-00774-4 41. Luo Tao, Li YT, Zhang WY, Liu JX, Shi HB. 2022. Rumen and fecal microbiota profiles associated with immunity of young and adult goats. Front Immubol. 13:978402. https://doi.org/10.3389/fimmu.2022.978402 42. Shi HB, Jiang NN, Wei L, Cai Jie, Zhan WY, Jiang QM, Loor JJ, Liu JX. 2022. AMPK-ChREBP axis mediates de novo milk fatty acid synthesis promoted by glucose in the mammary gland of lactating goat. Anim Nutr. 10:234-242 https://doi.org/10.1016/j.aninu.2022.05.003 43. Ding QC, Cao FW, Lai SL, Zhuge H, Chang KX, Valencak TG, Liu JX, Li ST, Ren Daxi. 2022. Lactobacillus plantarum ZY08 relieves chronic alcohol-induced hepatic steatosis and liver injury in mice via restoring intestinal flora homeostasis. Food Res Int. 157: 111259. https://doi.org/10.1016/j.foodres.2022.111259 44. Gao DY, Sun XB, Fang Y, He Bo, Wang JH, Liu JX, Wang JK, Wang Q. 2022. Heterologous expression and characterization of two novel glucanases derived from sheep rumen microbiota. Wld J Microbiol Biotechnol. 38:87 https://doi.org/10.1007/s11274-022-03269-6 45. Deng ZX, Hou KW, Valencak T, Luo X, Liu JX, Wang HF. 2022. AI-2/LuxS quorum sensing system promotes biofilm formation of Lactobacillus rhamnosus GG and enhances the resistance to Enterotoxigenic Escherichia coli in germ-free zebrafish. Microbiol Spectr. 10(4):e0061022 https://doi.org10.1128/spectrum.00610-22 46. Zhong YF, Wang SS, Di HQ, Deng ZX, Liu JX and Wang HF. 2022. Gut health benefit and application of postbiotics in animal production. J Anim Sci Biotechnol. 13:38-50. https://doi.org/10.1186/s40104-022-00688-1 47. Zhong YF, Cao JH, Ma YF, Liu JX and Wang HF. 2022. Fecal microbiota transplantation donor and dietary fiber intervention collectively contribute to gut health in a mouse model. Front Immunol. 13:842669. https://doi.org/10.3389/fimmu.2022.842669 48. Zhong YF, Fu DY, Deng ZX, Tang WJ, Mao JD, Zhu T, Zhang Y, Liu JX and Wang HF. 2022. Lactic acid bacteria mixture isolated from wild pig alleviated the gut inflammation of mice challenged by Escherichia coli. Front Immunol. 13:822754. https://doi.org/10.3389/fimmu.2022.822754 49. Tang WJ, Zhong YF, Wei YS, Deng ZX, Mao JD, Liu JL, Valencak TG, Liu JX, Xu HP, Wang HF. 2022. Ileum tissue single-cell mRNA sequencing elucidates the cellular architecture of pathophysiological changes associated with weaning in piglets, BMC Biol. 20:123. https://doi.org/10.1186/s12915-022-01321-3 2021 50. Xie YY, Miao C, Lu Y, Sun HZ, Liu JX. 2021. Nitrogen metabolism and mammary gland amino acid utilization in lactating dairy cows with different residual feed intake. Anim Biosci. 34(10):1600-1606. https://doi.org/10.5713/ab.20.0821 51. Sun HZ, Peng KL, Xue MY, Liu JX. 2021. Metagenomics discovers distinctive ruminal microbiome and resistome in dairy buffaloes. Anim Microbiome. 3(1):44 https://doi.org/10.1186/s42523-021-00103-6 52. Wang DM, Cai J, Wang BB, Ding SS, Guan LL, Liu JX. 2021. Integrative network analysis revealed molecular mechanisms of urine urea output in lactating dairy cows: potential solutions to reduce environmental nitrate contamination. Genomics. 113(3): 1522-1533 https://doi.org/10.1016/j.ygeno.2021.03.024 53. Gu FF, Jiang LY, Xie YY, Wang DM, Zhao FQ, Liu JX. 2021. Supplementing N-carbamoylglutamate in late gestation increases newborn calf weight by enhanced placental expression of mTOR and angiogenesis factors genes in dairy cows. Anim Nutr 7:981-988 https://doi.org/10.1016/j.aninu.2021.05.0072 54. Gu FF, Miao C, Jiang LY, Wang DM, Liu HY, Liu JX. Dietary supplementation with N-carbamoylglutamate initiated during the prepartum stage improves the lactation performance of postpartum dairy cows. Anim Nutr. 7:232-238 https://doi.org/10.1016/j.aninu.2020.07.002 55. Cai Jie, Miao Chao, Chen Yi, Xie YY, Liu JX, Wang DM, Liu JX. 2021. The effects of nano-sized zinc addition on lactation performance and mammary gland permeability of dairy cows. Anim Nutr 7:1024-1030 https://doi.org/10.1016/j.aninu.2021.06.003 56. Cai Jie, Zang XW, Wu ZZ, Liu JX, Wang DM. 2021. Altered protein S-glutathionylation depicts redox imbalance triggered by transition metal oxide nanoparticles in a breastfeeding system. NanoImpact. 22:100305 https://doi.org/10.1016/j.impact.2021.100305 57. Wu ZZ, Peng WC, Liu JX, Xu GZ, Wang DM. 2021. Effect of chromium methionine supplementation on lactationperformance, hepatic respiratory rate and anti-oxidative capacity in early-lactating dairy cows. Animal. 15:100326. https://doi.org/10.1016/j.animal.2021.100326 58. Gu FF, Liang SL, Zhu SL, Liu JX, Sun HZ. 2021. Multi-omics revealed the effects of rumen-protected methionine on the nutrient profile of milk in dairy cows. Food Res Int’l. 149: 110682 https://doi.org/10.1016/j.foodres.2021.110682 59. Xue MY, Xie YY, Zhong YF, Liu JX, Guan LL, Sun HZ. 2021. Ruminal resistome of dairy cattle is individualized and the resistotypes are associated with milking traits. Anim Microbiome. 3:18 https://doi.org/10.1186/s42523-021-00081-9 60. Wei ZH, Xie Xiao, Xue MY, Valencak TG, Liu JX, Sun HZ. 2021. The effects of non-fiber carbohydrate content and forage type on rumen microbiome of dairy cows. Animals. 11: 3519 https://doi.org/10.3390/ani11123519 61. Liang SL, Wu CQ, Peng WC, Liu JX, Sun HZ. 2021. Predicting daily dry matter intake using feed intake of first two hours after feeding in mid and late lactation dairy cows. Animals. 11:104. https://doi.org/10.3390/ani11010104 62. Lan W, Ren YF, Wang Z, Liu JX, Liu HY. 2021. Metabolic profile reveals the immunosuppressive mechanisms of methionyl-methionine in lipopolysaccharide-induced inflammation in bovine mammary epithelial cell. Animals. 11:833. https://doi.org/10.3390/ani11030833 63. Li Yan, Lv M, Wang JQ, Tian ZH, Yu Bo, Wang B, Liu JX, Liu HY. 2021. Dandelion (Taraxacum mongolicum Hand.-Mazz.) supplementation enhanced rumen fermentation through the interaction between ruminal microbiome and metabolome. Microorganisms. 9:83 https://doi.org/10.3390/microorganisms8010083 64. Cao FW, Liang MM, Liu JX, Renye Jr JA, Qi OX, Ren DX. 2021. Characterization of an exopolysaccharide (EPS-3A) produced by Streptococcus thermophilus ZJUIDS-2-01 isolated from traditional yak yogurt. Int J Biol Macromol. 192:1331-1343. https://doi.org/10.1016/j.ijbiomac.2021.10.055 65. Xu NN, Yang DT, Miao C, Valencak TC, Liu JX, Ren DX. 2021. Organic zinc supplementation in early-lactation dairy cows and its effects on zinc content and distribution in milk and cheese. JDS Commun. 2: 110–113 https://doi.org/10.3168/jdsc.2020-0070 66. Yao KY, Jiang LY, Liu JX, WangDM, Liu HY, Ren DX. 2021. Effect of yellow wine lees supplementation on milk antioxidant capacity and hematological parameters in lactating cows under heat stress. Animals. 11:2643. https://doi.org/10.3390/ani11092643 67. Li YT, Jiang NN, Zhang WY, Lv ZB, Liu JX, Shi HB. 2021. Bacillus amyloliquefaciens-9 reduces somatic cell count and modifies fecal microbiota in lactating goats. Marine Drugs. 19:404. https://doi.org/10.3390/md19080404 68. Tang WJ, Liu JL, Ma YF, We YS, Liu JX, Wang HF. 2021. Impairment of intestinal barrier function induced by early weaning via autophagy and apoptosis associated with gut microbiome and metabolites. Front Immunol. 12:804870. https://doi.org/10.3389/fimmu.2021.804870 2020 69. Deng ZX, Dai T, Zhang WM, Zhu JL, Luo X, Fu DY, Liu JX, Wang HF. 2020. Glyceraldehyde-3-phosphate dehydrogenase increases the adhesion of Lactobacillus reuteri to host mucin to enhance probiotic effects. Int’l J Mol Sci. 21: 9756. https://doi.org/10.3390/ijms21249756 70. Zhong YF, Xue MY, Sun HZ, Valencak TG, Guan LL, Liu JX. 2020. Rumen and hindgut bacteria are potential indicators for mastitis of mid lactating Holstein dairy cows. Microorganisms. 8:2042 https://doi.org/10.3390/microorganisms8122042 71. Xue MY, Sun HZ, Wu XH, Liu JX, Guan LL. 2020. Multi-omics reveals that the rumen microbiome and its metabolome together with the host metabolome contribute to individualized dairy cow performance. Microbiome. 8: 64 https://doi.org/10.1186/s40168-020-00819-8 72. Sun HZ, Zhou M, Wang Ou, Wang DM, Liu JX, Guan LL. 2020. Multi-omics reveals functional genomic and metabolic mechanisms of milk production and quality in dairy cows. Bioinformatics. 36(8): 2530-2537 https://doi.org/10.1093/bioinformatics/btz951 73. Cai J, Wang DM, Liang SL, Peng JR, Zhao FQ, Liu JX. 2020. Excessive supply of glucose elicits an NF-κB2-dependent glycolysis in lactating goat mammary glands. FASEB J. 34:8671-8685. https://doi.org/10.1096/fj.201903088R 74. Cai J, Wang DM, Zhao FQ, Liang SL, Lin SX, Liu JX. 2020. AMPK-mTOR pathway is involved in glucose-modulated amino acid sensing and utilization in the mammary glands of lactating goats. J Anim Sci Biotechnol. 11(1): 32. https://doi.org/10.1186/s40104-020-0434-6 75. Guan RW, Wang DM, Wang BB, Jiang LY, Liu JX. 2020. Prognostic potential of pre-partum blood biochemical and immune variables for postpartum mastitis risk in dairy cows. BMC Vet Res. 16: 136 https://doi.org/10.1186/s12917-020-02314-6 76. Yao KY, Wei ZH, Xie YY, Wang DM, Fang D, Ma MR, Liu JX. 2020. Lactation performance and nitrogen utilization of dairy cows on diets including unfermented or fermented yellow wine lees mix. Livest Sci. 236: 104025. https://doi.org/10.1016/j.livsci.2020.104025 77. Yao KY, Gu FF, Liu JX. 2020. In vitro rumen fermentation characteristics of substrate mixtures with soybean meal partially replaced by microbially-fermented yellow wine lees. Ital J Anim Sci. 19(1):18-24. https://doi.org/10.1080/1828051X.2019.1686433 78. Wang B, Yu Zhu, Liu JX. 2020. Assessing metabolic properties of dairy cows fed low quality straws by integrative arterial and venous metabolomics. Asian-Aust J Anim Sci. 33(11): 1770-1778 https://doi.org/10.5713/ajas.19.0527 79. Wu JJ, Liu JX, Wang DM. 2020. Effects of body condition on the insulin resistance, lipid metabolism and oxidative stress of lactating dairy cows. Lipids Health Dis.19(1):56 https://doi.org/10.1186/s12944-020-01233-7 80. Shi HB, Wang Chong, Tai DM, Liu JX, Loor Juan, Liu HY. 2020. Short Communication: the antilipogenic effect of tran-10, cis-12 CLA in bovine mammary epithelial cells is associated with proteasome activity and ATP production. J Dairy Sci. 103(10): 9096-9101 https://doi.org/ /10.3168/jds.2019-17872 81. Dai WT, Zhao FQ, Liu JX, Liu HY. 2020. ASCT2 is involved in SARS-mediated β-casein synthesis of bovine mammary epithelial cells with methionine supply. J Agri Food Chem. 68(46):13038-13045 https://doi.org/10.1021/acs.jafc.9b03833 82. Wang CH, Liu H, Wang C, Liu JX, Liu HY. 2021. Effects of dietary rumen-protected betaine on lactation performance and serum metabolites of mid-lactation Holstein dairy cows. J Agri Food Chem. 68(46):13154-13159 https://doi.org/10.1021/acs.jafc.9b07453 83. Lang W, Wang Z, Liu JX, Liu HY. 2020. Methionyl-methionine exerts anti-inflammatory effects through the JAK2-STAT5-NF-kappa B and MAPK signaling pathways in bovine mammary epithelial cells. J Agri Food Chem. 68(47):13742-13750 https://doi.org/10.1021/acs.jafc.0c05962 84. Chen Q, Zhao FQ, Ren YF, Han JL, Liu JX, Li Y, Liu HY. 2020. Parenterally delivered methionyl-methionine dipeptide during pregnancy enhances mammogenesis and lactation performance over free methionine by activating PI3K-AKT signaling in methionine-deficient mice. J Nutr.150(5): 1186-1195 https://doi.org/10.1093/jn/nxaa005 85. Wang CH, Zhao FQ, Liu JX, Liu HY. 2020. The essential role of N-glycosylation in the transport activity of bovine PepT2. J Dairy Sci. 103(07): 6679-6683 https://doi.org/10.3168/jds.2019-16858 86. Dai WT, Zhao FQ, Liu JX, Liu HY. 2020. Seryl-tRNA synthetase is involved in methionine stimulation of beta-casein synthesis in bovine mammary epithelial cells. Br J Nutr. 123(5): 489-498 https://doi.org/10.1017/S0007114519002885 87. Zhang WX, Zhang Y, Zhang XW, Deng ZX, Liu JX, He ML, Wang HF. 2020. Effects of dietary supplementation with combination of tributyrin and essential oil on gut health and microbiota of weaned piglets. Animals. 10:180. https://doi.org/https://doi.org/10.3390/ani10020180 88. Qi, SR, Cui YJ, Liu JX, Luo XM, Wang HF. 2020. Lactobacillus rhamnosus GG components, SLP, gDNA and CpG, exert protective effects on mouse macrophages upon lipopolysaccharide challenge. Lett App Microbiol. 70(2):118-127. https://doi.org/10.1111/lam.13255 89. Xu NN, Yang DT, Zhang BX, Liu JX, Ye JA, Ren DX. 2020. Short communication: Influence of intramuscular injection of vitamin B12 in early lactation dairy cows on low-moisture part-skim Mozzarella cheese quality and vitamin B12 stability. J Dairy Sci. 103(11): 9830-9840 https://doi.org/10.3168/jds.2020-18568 90. Zheng ZY, Cao FF, Wang WJ, Yu J, Chen C, Chen Bo, Liu JX, Firrman J, Renye J, Ren DX. 2020. Probiotic characteristics of lactobacillus plantarum e680 and its effect on hypercholesterolemic mice. BMC Microbiol. 20:239 https://doi.org/10.1186/s12866-020-01922-4 91. Li SS, Hu Q, Chen C, Liu JX, He GQ, Li L, Wu JP, Ren DX. 2020. Formation of bioactive peptides during simulated gastrointestinal digestion is affected by as1-casein polymorphism in buffalo milk. Food Chem. 313: 126159. https://doi.org/10.1016/j.foodchem.2020.126159 92. Gu FF, Wang DM, Yang DT, Liu JX, Ren DX. 2020. Short communication: Effect of dietary N-carbamoylglutamate supplementation on milk amino acid profile and mozzarella cheese quality in mid-lactating dairy cows. J Dairy Sci. 103(6): 6935-6940 https://doi.org/10.3168/jds.2019-17385 93. Liu L, Jiang RL, Liu JX, Bo L. 2020. The bovine Lactoferrin-Osteopontin complex increases proliferation of human intestinal epithelial cells by activating the PI3K/Akt signaling pathway. Food Chem. 320: 125919. https://doi.org/10.1016/j.foodchem.2019.125919