郭希山
博士 副教授
个人简介
1994-1999,浙江大学生物医学工程与仪器科学学院,生物医学工程专业(5年制本科) 1999-2005,浙江大学生物医学工程系,生物传感器国家专业实验室,硕博连读,导师叶学松教授(硕)、陈裕泉教授(博) 2002-2003,意大利比萨大学生物医学工程系E.Piaggio中心留学,嗅觉味觉传感器研究,导师Prof. D. De. Rossi 2005-2007,浙江大学生物系统工程系,博士后,合作导师王立人教授 2009-2011,美国加州大学伯克利分校传感器与执行器中心(BSAC)留学,导师Prof. Liwei Lin(林立伟) 2007-至今,浙江大学生物系统工程系,副教授。长期从事微纳传感器(气敏、离子敏、生物敏),生物医学传感器(POCT、超声换能器、射线探测器等),MEMS(压电微声器件、肖特基及场效应管传感器件、嗅觉芯片、味觉芯片等)、微弱信号检测技术等领域研究工作,以及食品安全快速检测技术,医疗仪器(慢病体外诊断,肿瘤早期检测,生命监护等),可穿戴设备(人体生理健康、动物生命体征)、农业传感器及仪器等应用开发工作。主持国家自然科学基金、863项目、国家重点专项计划项目子课题、国家科技支撑计划子课题、国家科学仪器重大专项子课题、浙江省自然科学基金和浙江省公益性项目10余项;已发表SCI/EI论文30余篇,其中在《Biosensors and Bioelectronics》、《Sensors and Actuators B Chemical》、《Electrochemistry Communications》、《Analyst》、《Microchimica Acta》、《Food Control》、《Sensors》、《Food Hydrocolloids》、《Transaction of ASABE》、《Bioresource Technology》等期刊发表论文20余篇,有两篇论文(电子舌、SAW免疫传感器)被国际生物医学搜索引擎数据库BioMedLib评为相关研究领域Top10论文第一名;申请国家发明专利近20项,已获授权13项,软件著作权登记15项。目前担任《Sensors》Subject editor,《Sensors and Actuators B Chemical》等SCI期刊长期特邀审稿人,IEEE会员,美国纳米学会会员,中国仪器仪表学会分析仪器分会会员等。指导的博士生获国家奖学金,指导的美国留学生关于致病菌微生物快速检测纳米传感器论文获2014年美国ASABE大会本科生组优秀论文奖第2名。近年来声表面波温度传感器,血糖、尿酸等POCT生物医学传感器,藻毒素、氯霉素、残留农药及孔雀石绿等食品安全检测试纸,溶解氧、氨氮、亚硝酸盐等电化学传感器,可穿戴生命体征监测手环,食品营养成分快速检测仪、冠心病无损诊断仪、婴儿监护仪、人体心肺功能非接触监测仪等产业化。 奖励荣誉 荣获2006年度浙江大学优秀博士后;2007年度院级先进工作者;2008年入选浙江大学“新星计划”。
研究领域
微纳传感器;MEMS;食品安全快速检测技术;医疗诊断技术及仪器;环境检测技术等。
近期论文
Study of direct electron transfer and enzyme activity of glucose oxidase on graphene surface, Electrochemistry Communications, 11/2014 2. Glucose biosensor based on a platinum electrode modified with rhodium nanoparticles and with glucose oxidase immobilized on gold nanoparticles, Microchimica Acta 01/2014; 181 3. Rapid Detection of Chloramphenicol Residues in Aquatic Products Using Colloidal Gold Immunochromatographic Assay, Sensors 2014, 14(11), 21872-21888 4. Gas-sensing characteristics of dielectrophoretically assembled composite film of oxygen plasma-treated SWCNTs and PEDOT/PSS polymer, Sensors and Actuators B 178 (2013) 279– 288 5. Comparison of the gel-forming ability and gel properties of α-lactalbumin, lysozyme and myoglobin in the presence of β-lactoglobulin under high pressure, Food Hydrocolloids 12/2013; 33(2):415–424 6. O2 plasma-functionalized SWCNTs and PEDOT/PSS composite film assembled by dielectrophoresis for ultrasensitive trimethylamine gas sensor, Analyst 07/2013 7. Fast and Sensitive Detection of Pb2+ in Foods Using Disposable Screen-Printed Electrode Modified by Reduced Graphene Oxide, Sensors 2013, 13, 13063-13075 8. Direct electron transfer glucose biosensor based on glucose oxidase self-assembled on electrochemically reduced carboxyl graphene, Biosensors & Bioelectronics 12/2012; 43:131-136 9. Developing a novel sensitive visual screening card for rapid detection of pesticide residues in food, Food Control. 03/2013; 30(1):15–23. 10. Polyaniline nanofiber gas sensors by direct-write electrospinning, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) 01/2011 11. A surface acoustic wave humidity sensor based on electrosprayed silicon-containing polyelectrolyte , Sensors and Actuators, B: Chemical,2010,145 (1),516-520 12. J. M. Jian, X. S. Guo, Q. Cai and L. W. Lin, Proceedings of the 16th International Conference on Solid-State Sensors, Actuators and Microsystems, 2011, pp. 2710–2713. 13. A wireless solution for greenhouse monitoring and control system based on ZigBee technology\[J\],JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE A,2007,8\(10\),1584-1587 14. A novel glucose sensor system with Au nanoparticles based on microdialysis and coenzymes for continuous glucose monitoring, Sensors and Actuators A Physical, 01/2005 15. A surface acoustic wave humidity sensor based on electrosprayed silicon-containing polyelectrolyte\[J\],Sensors and Actuators, B: Chemical,2010,145\(1\),516-520 16. Study of chemical sensors based on the composites of polymers and carbon black and its application on electronic tongues\[J\],Chinese Journal of Sensors and Actuators,2006,19\(3\),569-572 17. Surface acoustic wave gas sensors integrated GC separation column based on gas-liquid phase transition\[J\],Chinese Journal of Sensors and Actuators,2006,19\(2\),318-322 18. Magnetic nanowires based immunosensor and detecting system\[J\],Zhejiang Daxue Xuebao\(Gongxue Ban\)/Journal of Zhejiang University \(Engineering Science\),2009,43\(11\),2038-2042 19. Surface acoustic wave humidity microsensor based on electrospray polymer film\[J\], Transactions of the Chinese Society of Agricultural Engineering,2010,26\(10\),104-107 20. Annealing nano-to-micro contacts for improved contact resistance,Proc. NEMS, 2010.01 21. Design of wireless SAW humidity sensor node based on radio wake-up technique, International Conference on Communication Technology Proceedings, ICCT, p 17-20, 2010.01 22. A Design of Greenhouse Monitoring & Control System Based on ZigBee Wireless Sensor Network,Wireless Communications, Networking and Mobile Computing, p 2563-2567, 2007.10 23. The design of an IEEE1451-based low-cost embedded monitoring and control system dedicated for greenhouse, Proc., v 2, p 254-256, 2007, WMSCI 2007 24. Determination of chemical oxygen demand in wastewater by near-infrared spectroscopy,Zhejiang Daxue Xuebao (Gongxue Ban)/Journal of Zhejiang University (Engineering Science), v 41, n 5, p 752-755,2007.05 25. 基于酶抑制法的农药残留快速比色检测,《农业工程学报》,2014.06 26. 基于介电电泳组装技术的PEDOT/PSS-SWCNTs气体传感器的研究,《真空电子技术》,2013.02 27. 基于纳米金修饰丝网印刷电极的乙醇生物传感器, 《传感技术学报》,2009.12 28. 基于气液相转变效应的SAW气体传感器,《浙江大学学报工学版》,2007.04