范顺武，男，医学博士，教授，主任医师，博士生导师，国内知名脊柱外科专家。浙江大学医学院附属邵逸夫医院骨科主任，浙江大学求是特聘医师，中华医学会骨科分会委员，中国医教会腰椎分会副主任委员，浙江省医学会骨科分会主任委员，《中华骨科杂志》、《中国骨伤》编委，浙江省卫生领军人才，浙江省卫生高层次创新人才，浙江省支撑学科带头人。 获国家发明专利4项。出版专著4部，其中主编或副主编3部。发表论文200余篇，其中SCI论文48篇，其中IF>10.0论文6篇，IF>5.0论文21篇，SCI影响因子累计近达200余分，累计被他引400余次；另有两篇论文在中华骨科杂志领跑者5000-2014论文评选中分获全国第1和第10名，1998年至今在中华骨科杂志发文数量排全国第5名，带领的团队发文数量全国第11名。获浙江省科技进步一等奖1项、二等奖1项，浙江省医药卫生科技创新一等奖2项。近5年主持科技部国家重点研发计划1项，国家自然科学基金面上项目2项，省级重点项目2项，带领团队承担国家自然科学基金20余项。已培养博导2名、硕导7名、博士25名、硕士99名，培养的学生获挑战杯全国特等奖2人，中国青少年科技创新奖2人，浙江省优秀毕业生5人。 获奖 1、范顺武，方向前，赵凤东，胡志军，赵兴，张建锋，虞和君，周志杰，胡子昂，王吉莹；腰椎退变性疾患微创化治疗的技术和应用，浙江省科学技术进步奖一等奖，浙江省人民政府，2016年8月 2、范顺武，方向前，赵凤东，胡志军，赵兴，张建锋，虞和君，周志杰，胡子昂，王吉莹；腰椎退变性疾患微创化治疗的技术和应用，浙江省医药卫生科技奖一等奖，浙江省卫健委，2016年4月 3、方明,彭伟,范顺武,朱伟强,黄汐,许吉峰,郑应桃，可在体内多角度调节的额伸缩式人工椎体的研发，浙江省科技进步奖二等奖，浙江省人民政府，2018年10月

脊柱外科

2020年新发表代表论文： 1. Gangliang Wang , Shuai Chen , Ziang Xie, Shuying Shen , Wenbin Xu , Wenxiang Chen , Xiang Li , Yizheng Wu, Liangping Li , Bin Liu , Xianjun Ding , An Qin, Shunwu Fan*. TGFβ Attenuates Cartilage Extracellular Matrix Degradation via Enhancing FBXO6-mediated MMP14 Ubiquitination. Ann Rheum Dis. 2020 May 14;annrheumdis-2019-216911. IF:16.102 2、Chao Liu, Jiaxing You, Weifen Zhu, Yixin Chen, Shengyun Li, Yuefeng Zhu, Shujuan Ji, Ying Wang, Hongye Li, Lin Li, Shunwu Fan*. The COVID-19 outbreak negatively affects the delivery of care for patients with diabetic foot ulcers. Diabetes Care.2020 Oct;43(10):e125-e126. IF:16.019 3、Xianfeng Lin, Qingqing Wang, Chenhui Gu, Mobai Li, Kai Chen, Pengfei Chen, Zhibin Tang, Xin Liu, Haihua Pan, Zhaoming Liu, Ruikang Tang, Shunwu Fan. Smart Nanosacrificial Layer on the Bone Surface Prevents Osteoporosis through Acid-Base Neutralization Regulated Biocascade Effects. J Am Chem Soc. 2020 Oct 14;142(41):17543-17556. IF：14.612 4. Qiu Pengcheng, Li Mobai, Chen Kai, Fang Bin, Chen Pengfei, Tang Zhibin, Lin Xianfeng*, Fan Shunwu*. Periosteal matrix-derived hydrogel promotes bone repair through an early immune regulation coupled with enhanced angio- and osteogenesis. [J]. Biomaterials. 2020 Jan; 227: 119552.IF：10.317 2019年新发表代表论文： 1. Shen Shuying, Wu Yizheng, Chen Junxin, Xie Ziang, Huang Kangmao, Wang Gangliang, Yang Yute, Ni Weiyu, Chen Zhijun, Shi Peihua, Ma Yan*, Fan Shunwu*. CircSERPINE2 protects against osteoarthritis by targeting miR-1271 and ETS-related gene. [J]. Ann Rheum Dis. 2019 Mar 28; 78(6): 826-836.IF:16.102 2. Wu Yizheng, Xie Ziang, Chen Junxin, Chen Jiaxin, Ni Weiyu, Ma Yan, Huang Kangmao, Wang Gangliang, Wang Jiying, Ma Jianjun, Shen Shuying*, Fan Shunwu*. Circular RNA circTADA2A promotes osteosarcoma progression and metastasis by sponging miR-203a-3p and regulating CREB3 expression. [J]. molecular cancer. 2019 Apr 2; 18(1): 73.IF:15.302 3. Chen Wenxiang, Xie Ziang, Tang Pan, Wang Yongli, Jie Zhiwei, Qin An, Jiang Xuesheng, Hu Zhijun*, Fan Shunwu*. The emerging role of IMD 0354 on bone homeostasis by suppressing osteoclastogenesis and bone resorption, but without affecting bone formation. [J]. Cell Death Dis. 2019 Sep 10;10(9): 654.IF:5.959 4. Jie Zhiwei, Shen Shuying, Zhao Xiangde, Xu Wenbin, Zhang Xuyang, Huang Bao, Tang Pan, Qin An, Fan Shunwu*, Xie Ziang*. Activating β-catenin/Pax6 axis negatively regulates osteoclastogenesis by selectively inhibiting phosphorylation of p38/MAPK. [J]. The FASEB Journal. 2019 Mar; 33(3): 4236-4247. IF:5.595 2018年新发表代表论文： 1、 Zhao C, Wang S, Wang G, Su M, Song L, Chen J, Fan S, Lin X. Preparation of decellularized biphasic hierarchical myotendinous junction extracellular matrix for muscle regeneration. Acta Biomater. 2018 Mar 1;68:15-28. IF: 6.383 2、 Xie Z, Yu H, Sun X, Tang P, Jie Z, Chen S, Wang J, Qin A, Fan S. A Novel Diterpenoid Suppresses Osteoclastogenesis and Promotes Osteogenesis by Inhibiting Ifrd1-Mediated and IκBα-Mediated p65 Nuclear Translocation. J Bone Miner Res. 2018 Apr;33(4):667-678. IF: 6.314 3、Tang P, Gu JM, Xie ZA, Gu Y, Jie ZW, Huang KM, Wang JY, Fan SW, Jiang XS, Hu ZJ. Honokiol alleviates the degeneration of intervertebral disc via suppressing the activation of TXNIP-NLRP3 inflammasome signal pathway. Free Radic Biol Med. 2018 May 20;120:368-379. IF: 6.02 4、Wang Q, Mo J, Zhao C, Huang K, Feng M, He W, Wang J, Chen S, Xie 1, Ma J, Fan S. Raddeanin A suppresses breast cancer-associated osteolysis through inhibiting osteoclasts and breast cancer cells. Cell Death Dis. 2018 Mar 7;9(3):376. IF: 5.638 5、Lin X, Chen J, Qiu P, Zhang Q, Wang S, Su M, Chen Y, Jin K, Qin A, Fan S, Chen P, Zhao X. Biphasic hierarchical extracellular matrix scaffold for osteochondral defect regeneration. Osteoarthritis Cartilage. 2018 Mar;26(3):433-444. IF: 5.454 6、Lin X, Zhao C, Zhu P, Chen J, Yu H, Cai Y, Zhang Q, Qin A, Fan S. Periosteum Extracellular-Matrix-Mediated Acellular Mineralization during Bone Formation. Adv Healthc Mater. 2018 Feb;7(4). IF: 5.609 7、Wang G, Huang K, Dong Y, Chen S, Zhang J, Wang J, Xie Z, Lin X, Fang X, Fan S. Lycorine Suppresses Endplate-Chondrocyte Degeneration and Prevents Intervertebral Disc Degeneration by Inhibiting NF-κB Signalling Pathway. Cell Physiol Biochem. 2018;45(3):1252-1269. IF: 5.05