博士、教授、博士生导师(分子与细胞医学)专业。84年至89年，浙大医学院临床医学系，获医学学士学位；91年至94年，浙大医学院获医学硕士学位；02-05年浙江大学细胞生物学专业，博士研究生毕业(师从李继承教授)，获理学博士学位。96至97年在德国吕贝克医科大学学习，访问学者。03年至05年，香港中文大学医学院从事博士课题研究。2008年在香港大学化学系细胞生物学研究室访问学者，师从中科院院士孔祥复教授。获国家自然科学基金面上项目6项。中国神经科学学会、中国细胞生物学学会、美国神经科学学会、浙江省康复医学会和日本解剖学会会员，担任Brain behavior and Immunity和Brain Pathology等杂志审稿人。 博士和博士后招生专业 分子与细胞医学，代码1001Z2，【基础医学院】

脑缺血的分子机制 抑郁症的发病机制 iPS定向诱导分化神经元修复神经损伤机制研究老年痴呆症的发病机制 老年痴呆症的发病机制

中国神经科学学会、中国细胞生物学学会、美国神经科学学会、浙江省康复医学会和日本解剖学会会员，担任Brain behavior and Immunity和Brain Pathology等杂志审稿人。

1. Chen S, Chen F, Amin N, Ren Q, Ye S, Hu Z, Tan X, Jiang M, Fang M. Defects of parvalbumin-positive interneurons in the ventral dentate gyrus region are implicated depression-like behavior in mice. Brain Behav Immun. 2022 Jan;99:27-42. doi: 10.1016/j.bbi.2021.09.013. [Impactor factor 19.27] 2. Ye S, Fang L, Xie S, Hu Y, Chen S, Amin N, Fang M, Hu Z. Resveratrol alleviates postpartum depression-like behavior by activating autophagy via SIRT1 and inhibiting AKT/mTOR pathway. Behav Brain Res. 2022 Nov 7:114208. doi: 10.1016/j.bbr.2022.114208. Online ahead of print. 3. Xu Z, Bai S, Wu H, Fang M. Elevated retinal retinol-binding protein 4 levels in diabetic mice can induce retinal neurodegeneration through microglia. Microsc Res Tech. 2022 Nov 10. doi: 10.1002/jemt.24258. 4. Luo Y, Chen S, Wu F, Jiang C, Fang M. The identification of the key residues E829 and R845 involved in transient receptor potential melastatin 2 channel gating. Front Aging Neurosci. 2022 Oct 24;14:1033434. doi: 10.3389/fnagi.2022.1033434. 5. Lou C, Fang M, Ye S, Fang Z, Amin N, Chen Y. Fluoxetine protects against inflammation and promotes autophagy in mice model of post-traumatic stress disorder. Behav Brain Res. 2022 Sep 5;433:114004. doi: 10.1016/j.bbr.2022.114004. 6. Zhang P, Fang H, Lou C, Ye S, Shen G, Chen S, Amin N, Botchway BOA, Fang M. Enhanced Glial Reaction and Altered Neuronal Nitric Oxide Synthase are Implicated in Attention Deficit Hyperactivity Disorder. Front Cell Dev Biol. 2022 Jun 21;10:901093. doi: 10.3389/ fcell.2022.901093. 7.Amin N, Chen S, Ye S, Wu F, Hussien AB, Lou C, Hu Z, Wang Y, Wu J, Fang M. Thymoquinone has a synergistic effect with PHD inhibitors to ameliorate ischemic brain damage in mice. Phytomedicine. 2022 Sep;104:154298. doi: 10.1016/j.phymed.2022.154298. 8.Botchway BO, Okoye FC, Chen Y, Arthur WE, Fang M. Alzheimer Disease: Recent Updates on Apolipoprotein E and Gut Microbiome Mediation of Oxidative Stress, and Prospective Interventional Agents. Aging Dis. 2022 Feb 1;13(1):87-102. doi: 10.14336/AD.2021.0616. 9. Amin N, Du X, Chen S, Ren Q, Hussien AB, Botchway BOA, Hu Z, Fang M. Therapeutic impact of thymoquninone to alleviate ischemic brain injury via Nrf2/HO-1 pathway. Expert Opin Ther Targets. 2021 Jul;25(7):597-612. doi: 10.1080/14728222.2021.1952986. e 10. Amin N, Chen S, Ren Q, Tan X, Botchway BOA, Hu Z, Chen F, Ye S, Du X, Chen Z, Fang M. Hypoxia Inducible Factor-1α Attenuates Ischemic Brain Damage by Modulating Inflammatory Response and Glial Activity. Cells. 2021 Jun 1;10(6):1359. doi: 10.3390/cells10061359. 11. Xie S, Hu Y, Fang L, Chen S, Botchway BOA, Tan X, Fang M, Hu Z. The association of oxytocin with major depressive disorder: role of confounding effects of antidepressants. Rev Neurosci. 2021 May 14. doi: 10.1515/revneuro-2020-0128. 12. Chen F, Chen S, Liu J, Amin N, Jin W, Fang M. Agomelatine Softens Depressive-Like Behavior through the Regulation of Autophagy and Apoptosis.Biomed Res Int. 2021 Mar 17;2021:6664591. doi: 10.1155/2021/6664591. 13. Du X, Xu Y, Chen S, Fang M. Inhibited CSF1R Alleviates Ischemia Injury via Inhibition of Microglia M1 Polarization and NLRP3 Pathway.Neural Plast. 2020 Aug 28;2020:8825954. 14. Amin N, Xie S, Tan X, Chen Y, Ren Q, Botchway BOA, Hu S, Ma Y, Hu Z, Fang M. Optimized integration of fluoxetine and 7, 8-dihydroxyflavone as an efficient therapy for reversing depressive-like behavior in mice during the perimenopausal period. Prog Neuropsychopharmacol Biol Psychiatry. 2020 Jul 13;101:109939. 15. Ren Q, Hu Z, Jiang Y, Tan X, Botchway BOA, Amin N, Lin G, Geng Y, Fang M. SIRT1 Protects Against Apoptosis by Promoting Autophagy in the Oxygen Glucose Deprivation/Reperfusion-Induced Injury. Front Neurol. 2019 Dec 5;10:1289. 16. Zhu N, Ruan J, Yang X, Huang Y, Jiang Y, Wang Y, Cai D, Geng Y, Fang M. Triptolide improves spinal cord injury by promoting autophagy and inhibiting apoptosis. Cell Biol Int. 2020 Mar;44(3):785-794. 17. Amin N, Tan X, Ren Q, Zhu N, Botchway BOA, Hu Z, Fang M. Recent advances of induced pluripotent stem cells application in neurodegenerative diseases. Prog Neuropsychopharmacol Biol Psychiatry (2019). 18. Jiang Y, Botchway BOA, Hu Z, Fang M. Overexpression of SIRT1 Inhibits Corticosterone-Induced Autophagy. Neuroscience (2019). 19. Xiang M, Jiang Y, Hu Z, Yang Y, Du X, Botchway BO, Fang M. Serotonin receptors 2A and 1A modulate anxiety-like behavior in post-traumatic stress disordered mice. Am J Transl Res (2019). 20. Hu Z, Du X, Yang Y, Botchway BOA, Fang M. Progesterone and fluoxetine treatments of postpartum depressive-like behavior in rat model. Cell Biol Int (2019). 21. Liu X, Botchway BOA, Tan X, Zhang Y, Fang M. Resveratrol treatment of spinal cord injury in rat model. Microsc Res Tech (2018). 22.Liu JYH, Lin G, Fang M, Rudd JA. Localization of estrogen receptor ERα, ERβ and GPR30 on myenteric neurons of the gastrointestinal tract and their role in motility. Gen Comp Endocrinol (2018). 23.Tan X, Du X, Jiang Y, Botchway BOA, Hu Z, Fang M. Inhibition of Autophagy in Microglia Alters Depressive-Like Behavior via BDNF Pathway in Postpartum Depression. Front Psychiatry (2018). 24.Qin Y, Hu W, Yang Y, Hu Z, Li W, Fang M. Neuroprotective Effect of DAHP via Antiapoptosis in Cerebral Ischemia. Behav Neurol (2018). 25.Botchway BOA, Moore MK, Akinleye FO, Iyer IC, Fang M. Nutrition: Review on the Possible Treatment for Alzheimer's Disease. J Alzheimers Dis (2018). 26.Liu X, Zhang Y, Yang Y, Lin J, Huo X, Du X, Botchway BOA, Fang M. Therapeutic Effect of Curcumin and Methylprednisolone in the Rat Spinal Cord Injury. Anat Rec (Hoboken) (2018). 27.Yang Y, Fang M, Du X, Hu Z. Lucky gene 5-HTTLPR and postpartum depression: A systematic review. Neuro Endocrinol Lett (2017). 28.Xiang M, Jiang Y, Hu Z, Yang Y, Botchway BOA, Fang M. Stimulation of Anxiety-Like Behavior via ERK Pathway by Competitive Serotonin Receptors 2A and 1A in Post-Traumatic Stress Disordered Mice. Neurosignals (2017). 29.Du X, Huo X, Yang Y, Hu Z, Botchway BOA, Jiang Y, Fang M. miR-124 downregulates BACE 1 and alters autophagy in APP/PS1 transgenic mice. Toxicol Lett (2017). 30.Hu Z, Jiang Y, Huo X, Yang Y, Davies H, Botchway BOA, Fang M. Prospective Role of MicroRNAs in Depression. Curr Med Chem (2017). 31. Wang C, Hu Z, Zou Y, Xiang M, Jiang Y, Botchway BOA, Huo X, Du X, Fang M. The post-therapeutic effect of rapamycin in mild traumatic brain-injured rats ensuing in the upregulation of autophagy and mitophagy. Cell Biol Int (2017). 32. Wang C, Sun C, Hu Z, Huo X, Yang Y, Liu X, Botchway BOA, Davies H, Fang M. Improved Neural Regeneration with Olfactory Ensheathing Cell Inoculated PLGA Scaffolds in Spinal Cord Injury Adult Rats. Neurosignals (2017).