基本概况 1990年5月获美国爱达荷大学昆虫学专业理学博士学位。现任浙江大学生命科学学院微生物研究所所长，浙江大学求是特聘教授。长期从事昆虫病理学、昆虫流行病学和害虫微生物防治领域的跨学科研究，主攻昆虫病原真菌的表观遗传学、分子与细胞生物学、生物技术研究及真菌杀虫剂的研发和遗传改良。先后主持国家“863计划”和“973计划”的课题4项，国家自然科学基金重点和面上项目共14项，目前在研项目包括国家重点研发计划课题1项和国家自然科学基金项目2项。迄今共发表各种学术论著300余篇，2/3以上发表于微生物学、植物保护及生物技术领域的SCI源国际期刊，其中30余篇SCI论文发表于Environmental Microbiology权威期刊，个人SCI-H指数达到37。 主要荣誉 国家杰出青年科学基金获得者（1995），当选“长江学者奖励计划”特聘教授（2001），领衔入选教育部“农业害虫生物防治”创新团队（2005），入选浙江省有突出贡献中青年专家（2007），作为核心骨干入选国家自然科学基金“农业害虫生物防治的基础研究”创新群体（2010）。获浙江省科学技术一等奖二项（2007年度排名1/8, 2015年度排名8/16）与教育部科技进步二等奖一项（1998年度排名1/1）。2014~2017连续四年入选爱思维尔农业与生物科学领域的中国高被引学者。 出版著作 1. 唐启义, 冯明光（著）. DPSÓ数据处理系统: 实验设计、统计分析及数据挖掘. 北京: 科学出版社, 2007, 1100 pp. (统一书号：ISBN978-7-03-018047-6, 134.9万字) 2. 冯明光. 决定我国真菌杀虫剂新兴产业发展的关键技术与社会因素. 见:农业微生物研究及产业化进展(喻子牛和陈守文主编). 北京：中国农业出版社. 2004, 129~135. 3. 应盛华, 冯明光. 丝孢类生防真菌制剂研制的技术瓶颈与改进途径. 见: 中国虫生真菌研究与应用, 卷5 (刘杏忠等主编). 北京: 中国农业科学技术出版社. 2003, 64~74. 4. Feng, M.G. Microbial control of insect pests with entomopathogenic fungi in China: A decade’s progress in research and utilization. In: R. K. Upadhyay (ed): Advances in Microbial Control of Insect Pests. New York: Kluwer Academic / Plenum Publishers, 2003, pp. 213-234. 5. 唐启义, 冯明光（著）. 实用统计分析及其DPS数据处理系统. 北京: 科学出版社. 2002, 648 pp. (统一书号：ISBN 7-03-009844-7, 83.6万字) 6. 唐启义, 冯明光（著）. 实用统计分析及其DPS数据处理系统. 北京: 科学出版社. 2002 (电子书号：ISBN 7-900122-07-9/Q.1, 源程序14万余行)

微生物学 昆虫病原真菌与害虫生物防治 昆虫病原真菌的遗传学、分子与细胞生物学、生物技术及遗传改良

中国农业生物技术学会常务理事，中国农业生物技术学会微生物分会副会长。

2011年以来发表的SCI论文(*通讯作者)： Ying SH, Feng MG*. Insight into vital role of autophagy in sustaining biological control potential of fungal pathogens against pest insects and nematodes. Virulence, accepted on 24 Aug 2018. Peng YJ, Ding JL, Feng MG, Ying SH*. Glc8, a regulator of protein phosphatase type 1, mediates oxidation tolerance, asexual development and virulence in Beauveria bassiana, a filamentous entomopathogenic fungus. Current Genetics, 2018, DOI: 10.1007/s00294-018-0876-y Zhu XG, Tong SM, Ying SH, Feng MG*. Antioxidant activities of four superoxide dismutases in Metarhizium robertsii and their contributions to pest control potential. Applied Microbiology and Biotechnology, accepted on 2 Aug 2018. Ding JL, Peng YJ, Chu XL, Feng MG, Ying SH*. Autophagy-related gene BbATG11 is indispensable for pexophagy and mitophagy and contributes to stress response, conidiation and virulence in the insect mycopathogen Beauveria bassiana. Environmental Microbiology, 2018, DOI:10.1111/1462-2920.14329 Cai Q, Wang JJ, Shao W, Ying SH, Feng MG*. Rtt109-dependent histone H3K56 acetylation and gene activity are essential for the biological control potential of Beauveria bassiana. Pest Management Science, DOI: 10.1002/ps.5054. Zhou G, Ying SH, Hu Y, Xiang F, Feng MG*, Wang J*. Roles of three HSF domain-containing proteins in mediating heat-shock protein genes and sustaining asexual cycle, stress tolerance and virulence in Beauveria basssiana. Frontiers in Microbiology, 2018, 9: 1677 (doi:10.3389/fmicb.2018.01677) Wang ZK, Cai Q, Tong SM, Ying SH, Feng MG*. C-terminal Ser/Thr residues are vital for the regulatory role of Ste7 in the asexual cycle and virulence of Beauveria bassiana. Applied Microbiology and Biotechnology, 2018, 102: 6973–6986. Zhang LB, Feng MG*. Antioxidant enzymes and their contributions to biological control potential of fungal insect pathogens. Applied Microbiology and Biotechnology, 2018, 102(12): 4995-5004. Cai Q, Wang JJ, Fu B, Ying SH, Feng MG*. Gcn5-dependent histone H3 acetylation and gene activity is required for the asexual development and virulence of Beauveria bassiana. Environmental Microbiology, 2018, 20(4): 1484-1497. Cai Q, Wang ZK, Shao W, Ying SH, Feng MG*. Essential role of Rpd3-dependent lysine modification in the growth, development and virulence of Beauveria bassiana. Environmental Microbiology, 2018, 20(4): 1590-1606. Cai Q, Tong SM, Shao W, Ying SH, Feng MG*. Pleiotropic effects of the histone deacetylase Hos2 linked to H4-K16 deacetylation, H3-K56 acetylation and H2A-S129 phosphorylation in Beauveria bassiana. Cellular Microbiology, 2018, 20: e12839. https://doi.org/10.1111/cmi.12839. Liu J, Sun HH, Ying SH, Feng MG*. Characterization of three mitogen-activated protein kinase kinase-like proteins in Beauveria bassiana. Fungal Genetics Biology, 2018, 113(1): 24-31. Chu XL, Dong WX, Ding JL, Feng MG, Ying SH*. Interactome analysis of transcriptional coactivator multiprotein bridging factor 1 unveils a yeast AP-1-like transcription factor involved in oxidation tolerance of mycopathogen Beauveria bassiana. Current Genetics, 2018, 64(1): 275-284. Wang JJ, Cai Q, Qiu L, Ying SH, Feng MG*. The histone acetyltransferase Mst2 sustains the biological control potential of a fungal insect pathogen through transcriptional regulation. Applied Microbiology and Biotechnology, 2018, 102(3): 1343–1355. Tong SM, Zhang AX, Guo CT, Ying SH, Feng MG*. Daylight length-dependent translocation of VIVID photoreceptor in cells and its essential role in conidiation and virulence of Beauveria bassiana. Environmental Microbiology, 2018, 20(1): 169-185. Gao Y, Feng MG, Ying SH*. Oxaloacetate hydrolase gene links the cytoplasmic route of oxalate formation to differentiation and virulence of entomopathogenic fungus Beauveria bassiana. Journal of Asian Entomology, 2018, 21: 211-216. Dong WX, Ding JL, Gao Y, Peng YJ, Feng MG*, Ying SH*. Transcriptomic insights into the alternative splicing-mediated adaptation of the entomopathogenic fungus Beauveria bassiana to host niches: autophagy- related gene 8 as an example. Environmental Microbiology, 2017, 19(10): 4126-4139. Zhu XG, Chu ZJ, Ying SH, Feng MG*. Lysyl-tRNA synthetase (Krs) acts a virulence factor of Beauveria bassiana by its vital role in conidial germination and dimorphic transition. Fungal Biology, 2017, 121(11): 956-965. Liu J, Tong SM, Qiu L, Ying SH, Feng MG*. Two histidine kinases can sense different stress cues for activation of the MAPK Hog1 cascade in a fungal insect pathogen. Environmental Microbiology, 2017, 19(10): 4091-4102. Liu J, Sun HH, Ying SH, Feng MG*. The Hog1-like MAPK Mpk3 collaborates with Hog1 in response to heat shock and functions in sustaining the biological control potential of a fungal insect pathogen. Applied Microbiology and Biotechnology, 2017, 101: 6941-6949. Chu ZJ, Sun HH, Zhu XG, Ying SH, Feng MG*. Discovery of a new intravacuolar protein required for the autophagy, development and virulence of Beauveria bassiana. Environmental Microbiology, 2017, 19(7): 2806-2818. Chu ZJ, Sun HH, Ying SH, Feng MG*. Vital role for cyclophilin B (CypB) in asexual development, dimorphic transition and virulence of Beauveria bassiana. Fungal Genetics and Biology, 2017, 105: 8-15. Wang JJ, Cai Q, Qiu L, Ying SH, Feng MG*. Additive roles of two TPS genes in trehalose synthesis, conidiation, multiple stress responses and host infection of a fungal insect pathogen. Applied Microbiology and Biotechnology, 2017, 101: 3637–3651. Liu J, Wang ZK, Sun HH, Ying SH, Feng MG*. Characterization of the Hog1 MAPK pathway in the entomopathogenic fungus Beauveria bassiana. Environmental Microbiology, 2017, 19(5): 1808-1821. Zhang LB, Tang L, Ying SH*, Feng MG. Two eisosome proteins play opposite roles in autophagic control and sustain cell integrity, function and pathogenicity in Beauveria bassiana. Environmental Microbiology, 2017, 19(5): 2037-2052. Wang J, Zhu XG, Ying SH, Feng MG*. Differential roles of six P-type calcium ATPases in sustaining intracellular Ca2+ homeostasis, asexual cycle and environmental fitness of Beauveria bassiana. Scientific Reports, 2017, 7: 1420. DOI:10.1038/s41598-017-01570-1. Wang ZK, Cai Q, Liu J, Ying SH, Feng MG. Global insight into lysine acetylation events and their links to biological aspects in Beauveria bassiana, a fungal insect pathogen. Scientific Reports, 2017, 7: 44360; DOI: 10.1038/srep44360. Wang J, Ying SH, Hu Y, Feng MG*. Vital role for the J-domain protein Mdj1 in asexual development, multiple stress tolerance and virulence of Beauveria bassiana. Applied Microbiology and Biotechnology, 2017, 101(1): 185-195. Zhu J, Zhu XG, Ying SH, Feng MG*. Effect of vacuolar ATPase subunit H (VmaH) on cellular pH, asexual cycle, stress tolerance and virulence in Beauveria bassiana. Fungal Genetics and Biology, 2017, 98(1): 52-60. Dong WX, Feng MG, Ying SH*. Use of quantitative PCR technique for determining gene copy number in the genome of Beauveria bassiana transformant. Journal of Asia-Pacific Entomology, 2017, 20(1): 57-59. He PH, Dong WX, Chu XL, Feng MG, Ying SH. The cellular proteome is affected by a gelsolin (BbGEL1) during morphological transitions in aerobic surface versus liquid growth in the entomopathogenic fungus Beauveria bassiana. Environmental Microbiology, 2016, 18(11): 4153-4169. Zhang LB, Tang L, Ying SH, Feng MG*. Distinct roles of cytoplasmic thioredoxin reductases Trr1 and Trr2 in the redox system involving cysteine synthesis and host infection of a fungal insect pathogen. Applied Microbiology and Biotechnology, 2016, 100: 10363-10374. Zhu J, Ying SH, Feng MG*. The Na+/H+ antiporter Nhx1 controls vacuolar fusion indispensible for the life cycle in vitro and in vivo of a fungal insect pathogen. Environmental Microbiology, 2016, 18(11): 3884-3895. Tong SM, Feng MG*. A mixture of putative sodium salts of camptothecin and bamboo tar is a novel botanical insecticide against rice pla+nthoppers and stem borers. Journal of Pest Science, 2016, 89: 1003-1011. Ying SH*, Liu J, Chu XL, Xie XQ, Feng MG. The autophagy-related genes BbATG1 and BbATG8 have different functions in differentiation, stress resistance and virulence of mycopathogen Beauveria bassiana. Scientific Reports, 2016, 6: 26376. DOI: 10.1038/srep26376. Zhang LB, Tang L, Ying SH, Feng MG*. Regulative roles of glutathione reductase and four glutaredoxins in glutathione redox, antioxidant activity and iron homeostasis of Beauveria bassiana. Applied Microbiology and Biotechnology, 2016, 100: 5907-5917. Guan Y, Wang DY, Ying SH, Feng MG*. Miro GTPase controls mitochondrial behavior affecting stress tolerance and virulence of a fungal insect pathogen. Fungal Genetics and Biology, 2016, 93: 1-9. Tong SM, Feng MG. Aphidicidal activity of a novel botanical insecticide made by alkalization of bamboo tar. Crop Protection, 2016, 87: 85-89. Zhu J, Ying SH, Feng MG*. The Pal pathway required for ambient pH adaptation regulates growth, conidiation and osmotolerance of Beauveria bassiana in a pH-dependent manner. Applied Microbiology and Biotechnology, 2016, 100: 4423-4433. Wang ZK, Wang J, Liu J, Ying SH, Peng XJ, Feng MG*. Proteomic and phosphoprotemic insights into Cdc14 signaling hub vital for asexual development and multistress responses of Beauveria bassiana. PLoS ONE, 2016, 11(4): e0153007. doi:10.1371/journal.pone.0153007. Chu ZJ, Wang YJ, Ying SH, Wang XW, Feng MG*. Genome-wide host-pathogen interaction unveiled by transcriptomic response of diamondback moth to fungal infection. PLoS ONE, 2016, 11(4): e0152908. doi:10.1371/journal.pone.0152908. Wang J, Ying SH, Hu Y, Feng MG*. Mas5, a homologue of bacterial DnaJ, is indispensable for the host infection and environmental adaptation of a filamentous fungal insect pathogen. Environmental Microbiology, 2016, 18(3): 1037-1047. Tong SM, Chen Y, Zhu J, Ying SH, Feng MG*. Subcellular localization of five singular WSC domain-containing proteins and their roles in Beauveria bassiana responses to stress cues and metal ions. Environmental Microbiology Reports, 2016, 8(2): 295-304. Tong SM, Feng MG*. Laboratory and field evaluations of camptothecin sodium salt against phytophagous mites. Pest Management Science, 2016, 72: 629–636. Tong SM, Chen Y, Ying SH, Feng MG*. Three DUF1996 proteins localize in vacuoles and function in fungal responses to multiple stresses and metal ions. Scientific Reports, 2016, 6: 20566; doi:10.1038/ srep20566. Chu XL, Feng MG, Ying SH*. Qualitative ubiquitome unveils the potential significances of protein lysine ubiquitination in hyphal growth of Aspergillus nidulans. Current Genetics, 2016, 62(1): 191-201. Li F, Shi HQ, Ying SH, Feng MG*. WetA and VosA are distinct regulators of conidiation capacity, conidial quality, and biological control potential of a fungal insect pathogen. Applied Microbiology and Biotechnology, 2015, 99: 10069-10081. Chu XL, Feng MG, Ying SH*. Transcriptomic analysis reveals the potential antioxidant pathways regulated by multiprotein bridging factor 1 (BbMBF1) in the fungal entomopathogen Beauveria bassiana. Biocontrol Science and Technology, 2015, 25(11): 134-1358. Guan Y, Wang DY, Ying SH, Feng MG*. A novel Ras GTPase (Ras3) regulates conidiation, multi-stress tolerance and virulence by acting upstream of Hog1 signaling pathway in Beauveria bassiana. Fungal Genetics and Biology, 2015, 82: 85-94. Li F, Shi HQ, Ying SH, Feng MG*. Distinct contributions of one Fe- and two Cu/Zn-cofactored superoxide dismutases to antioxidation, UV tolerance and virulence of Beauveria bassiana. Fungal Genetics and Biology, 2015, 81: 160-171. Wang JJ, Qiu L, Cai Q, Ying SH, Feng MG*. Transcriptional control of fungal cell cycle and cellular events by Fkh2, a forkhead transcription factor in an insect pathogen. Scientific Reports, 2015, 5: 10108. doi: 10.1038/ srep10108. Zhang LB, Tang L, Ying SH, Feng MG*. Subcellular localization of six thioredoxins and their antioxidant activity and contributions to biological control potential in Beauveria bassiana. Fungal Genetics and Biology, 2015, 76: 1-9. He PH, Wang XX, Chu XL, Feng MG, Ying SH*. RNA sequencing analysis identifies the metabolic and developmental genes regulated by BbSNF1 during conidiation of the entomopathogenic fungus Beauveria bassiana. Current Genetics, 2015, 61(2): 143-152. Liu Q, Li JG, Ying SH, Wang JJ, Sun WL, Tian CG, Fend MG*. Unveiling equal importance of two 14-3-3 proteins for morphogenesis, conidiation, multistress tolerance and virulence of an insect pathogen. Environmental Microbiology, 2015, 17(4): 1444-1462. Qiu L, Wang JJ, Ying SH, Feng MG*. Wee1 and Cdc25 control morphogenesis, virulence and multistress tolerance of Beauveria bassiana by balancing cell cycle-required cyclin-dependent kinase 1 activity. Environmental Microbiology, 2015, 17(4): 1119-1133. Li F, Wang ZL, Zhang LB, Ying SH, Feng MG. The role of three calcineurin subunits and a related transcription factor (Crz1) in conidiation, multistress tolerance and virulence of Beauveria bassiana. Applied Microbiology and Biotechnology, 2015, 99(2): 827-840. Wang XX, He PH, Feng MG, Ying SH*. BbSNF1 contributes to cell differentiation, extracellular acidification and virulence in Beauveria bassiana, a filamentous entomopathogenic fungus. Applied Microbioloty and Biotechnology, 2014, 98(20): 8657-8673. Hu Y, Wang J, Ying SH, Feng MG*. Five vacuolar Ca2+ exchangers play different roles in calcineurin-dependent Ca2+/Mn2+ tolerance, multistress responses and virulence of a filamentous entomopathogen. Fungal Genetics and Biology, 2014, 73(1): 12-19. Wang JJ, Qiu L, Cai Q, Ying SH, Feng MG*. Three a-1,2-mannosyltransferases contribute differentially to conidiation, cell wall integrity, multistress tolerance and virulence of Beauveria bassiana. Fungal Genetics and Biology, 2014, 70(1): 1-10. Zhang L, Ying SH, Feng MG*. Assessment of oral virulence against Spodoptera litura, acquired by a previously non-pathogenic Metarhizium anisopliae isolate, following integration of a midgut-specific insecticidal toxin. Biological Control, 2014, 79(1): 8-15. Qiu L, Wang JJ, Chu ZJ, Ying SH, Feng MG*. Phytochrome controls conidiation in response to red/far-red light and daylight length and regulates multi-stress tolerance in Beauveria bassiana. Environmental Microbiology, 2014, 16(7): 2316-2328. Wang JJ, Qiu L, Chu ZJ, Ying SH, Feng MG*. The connection of protein O-mannosyltransferase family to the biocontrol potential of Beauveria bassiana, a fungal entomopathogen. Glycobiology, 2014, 24(7): 638-648. Wang J, Zhou G, Ying SH, Feng MG*. Adenylate cyclase orthologues in two filamentous entomopathogens contribute differentially to growth, conidiation, pathogenicity and multi-stress responses. Fungal Biology, 2014, 118: 422-431. Ying SH*, Ji XP, Wang XX, Feng MG, Keyhani NO. The transcriptional co-activator multiprotein bridging factor 1 from the fungal insect pathogen, Beauveria bassiana, mediates regulation of hyphal morphogenesis, stress tolerance, and virulence. Environmental Microbiology, 2014, 16(6): 1879-1897. Wang ZL, Li F, Li C, Feng MG*. Bbssk1, a response regulator required for conidiation, multi-stress tolerance, and virulence of Beauveria bassiana. Applied Microbioloty and Biotechnology, 2014, 98(12): 5607-5618. doi: 10.1007/s00253-014- 5644-4. Chen Y, Zhu J, Ying SH, Feng MG*. The GPI-anchored protein Ecm33 is vital for conidiation, cell wall integrity and multi-stress tolerance of two filamentous entomopathogens but not for virulence. Applied Microbiology and Biotechnology, 2014, 98(12): 5517-5529. doi:10.1007/s00253-014-5577-y. Zhang L, Shi WB, Feng MG*. Histopathological and molecular insights into the ovicidal activities of two entomopathogenic fungi against two-spotted spider mite. Journal of Invertebrate Pathology, 2014, 117: 73-78. Chen Y, Zhu J, Ying SH, Feng MG*. Three mitogen-activated protein kinases required for cell wall integrity contribute greatly to biocontrol potential of a fungal entomopathogen. PLoS ONE, 2014, 9(2): e87948. DOI: 10.1371/journal.pone.0087948. Wang CS, Feng MG*. Advances in fundamental and applied studies in China of fungal biocontrol agents for use against arthropod pests. Biological Control, 2014, 68(1): 129-135.